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The map label for this gene is betT [C]

Identifier: 167624742

GI number: 167624742

Start: 3433847

End: 3435823

Strand: Reverse

Name: betT [C]

Synonym: Shal_2825

Alternate gene names: 167624742

Gene position: 3435823-3433847 (Counterclockwise)

Preceding gene: 167624743

Following gene: 167624741

Centisome position: 65.73

GC content: 44.61

Gene sequence:

>1977_bases
ATGTCGATAAAATCGAGTATTAATCCACCTGTTTTTTTCTCTTCAGTCATTTTGATTACATTAATGGTGGTTGTTTGTGC
TGTTTGGCCCACTCAATCACAAGATATCTTCAAAACGGCTCAATCCTGGTTTGAGCTTAAAGCCGGTTGGCTTTATATCC
TAGGCGTTGCAATCTTTCTTATTTTTATCATCTTCGTGATGGTGAGTCGTTTCGGCGACATCAAGCTAGGCCCAGATCAT
GCAGAGCCTGATTATACTTATAAGAGCTGGATCGCAATGTTGTTCTCAGCGGGTATGGGGATCGGCTTGATGTTCTTCGG
TGTCGCAGAGCCCGTGATGCACTACATGGCTCCGCCAGATGCGGATCCATTGACAATTCAAGCTGCAAAAGATGCCATGA
AGATCACTTTCTTCCACTGGGGGATCCATGCTTGGGCTATCTATGCGGTAGTGGCATTAAGCTTGGCGTATTTCTCATAC
CGTCATAAGCTCCCCTTACTACCAAGAAGTGCCTTGTACCCGTTAATTGGTGACAAAATTTATGGCCCAATTGGCCATGC
TGTCGATACATTTGCGGTACTCGGTACCATGTTCGGTGTGGCGACATCACTGGGTTTTGGTGTACTACAGCTTAACTCTG
GCCTTAACTATCTATTAGATGTACCTGTGAACACGACGGTACAAGTTGGTTTGATTATTGGTGTCTGTCTTATTGCGACA
GTGTCGGTGTTCTCAGGATTAGACAAAGGTGTTAAACGCTTAAGTGAGTTAAATCTATTCTTAGCGGTATTGCTGCTATT
GTTTGTGCTTGTATTTGGCCCAACGGTTGAATTACTACAAGCATTCGTGCAAAACACTGGCGCCTATTTAAGTGATATCG
TCGGTAAGACGTTTAACCTTTACGCTTATGAGCAAAAGAACGACTGGATTGGTGGTTGGACTCTACTTTATTGGGGCTGG
TGGATTTCATGGTCTCCATTCGTCGGTACCTTTATTGCCCGCGTTTCTCGTGGTCGTACCATTCGTGAATTCTTAGTGGG
TGTATTGTTTGTACCATCTGCATTGACCTTCCTCTGGATGACAGGCTTTGGTAACAGCGCCATTGATGTGATTGCAAATG
GCGGAACCTACCTGTCTGATGCGGTATCATCTGATGTATCGGTTGCCCTATTCGTGTTCTTTGAGCATCTGCCATTTTCA
ACCTTGCTGTCGACGATTGCACTTTGTCTCGTTGTCACCTTCTTCGTGACATCATCAGACTCAGGTTCATTGGTTATCGA
TAACCTTACCTCTGGTGGCGATCATAACGCACCTGTTTGGCAGCGTATTTTTTGGGCTTTAATGCAAGGTGTTGTTGCGT
CAGTATTGTTGTTGGCCGGTGGTCTACAAGCGCTTCAAACAGCCGCGATTGCTAGCGCATTGCCGTTCTTAATCGTTATG
CTTTTGATGTGTTTTGGTCTATACAAAGCATTAAAAGATGATTGGTTGAAGATCAACAGTGTTCAGTCTCACAATACCAG
TGTGCAGTTCACTAAGACCAACGTGAGTTGGGAGTCACATATCGATGTGTTGCTATCTCATCCAAGTCAGCAAGAAGCAC
AGGACTTCCTCGATAAGGTGGCTCAGCCTGCATTGTCTAAAGTGTGTGAAAGCTTCTTAAGCCGCTCAATTTCGGCAGAG
ATCTTAAACTTTGATAACCGTGTACGCTTTGTGGTGCCAAGTGAAGATCATAATGATTTCGTTTATGGTCTGCGTACCCG
CGGATTTAGTATTACTAACCCGCTTGAAAGTGAAGTGGCTGATGGTGATACCGAATACTACCGTGTGGAAGTGTTCCTAG
AGCACGGTGGTCAGCATTACGACGTGATGGGCTTCACTCAAGATCAGATCCTAGCGGACGTAGTTACGCAATACGAAAAG
TATCTGCATTACCTACATCTTTCAAGTTCTGAATATTTAGGTAGCGAAGCTAACTAA

Upstream 100 bases:

>100_bases
GCCAGTGTATTCTTATATTAGTTAATACGCATCAATCTCTGGCGGCCTTGTCGCGCAAGGCTAGAATTTTTGCGTGTACT
TCATCAACCGCGGTAACTAT

Downstream 100 bases:

>100_bases
TCAAGGTAAACTTTGCGGTGAAATCTACCTAGACTCAATGGTACAATTGAGTCTAGTAACAAACTTTAATGAGAAAGAGC
ATGTCGACCAATCAAGGGCA

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 657

Protein sequence:

>658_residues
MSIKSSINPPVFFSSVILITLMVVVCAVWPTQSQDIFKTAQSWFELKAGWLYILGVAIFLIFIIFVMVSRFGDIKLGPDH
AEPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMAPPDADPLTIQAAKDAMKITFFHWGIHAWAIYAVVALSLAYFSY
RHKLPLLPRSALYPLIGDKIYGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLDVPVNTTVQVGLIIGVCLIAT
VSVFSGLDKGVKRLSELNLFLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNLYAYEQKNDWIGGWTLLYWGW
WISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWMTGFGNSAIDVIANGGTYLSDAVSSDVSVALFVFFEHLPFS
TLLSTIALCLVVTFFVTSSDSGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVM
LLMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKVAQPALSKVCESFLSRSISAE
ILNFDNRVRFVVPSEDHNDFVYGLRTRGFSITNPLESEVADGDTEYYRVEVFLEHGGQHYDVMGFTQDQILADVVTQYEK
YLHYLHLSSSEYLGSEAN

Sequences:

>Translated_658_residues
MSIKSSINPPVFFSSVILITLMVVVCAVWPTQSQDIFKTAQSWFELKAGWLYILGVAIFLIFIIFVMVSRFGDIKLGPDH
AEPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMAPPDADPLTIQAAKDAMKITFFHWGIHAWAIYAVVALSLAYFSY
RHKLPLLPRSALYPLIGDKIYGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLDVPVNTTVQVGLIIGVCLIAT
VSVFSGLDKGVKRLSELNLFLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNLYAYEQKNDWIGGWTLLYWGW
WISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWMTGFGNSAIDVIANGGTYLSDAVSSDVSVALFVFFEHLPFS
TLLSTIALCLVVTFFVTSSDSGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVM
LLMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKVAQPALSKVCESFLSRSISAE
ILNFDNRVRFVVPSEDHNDFVYGLRTRGFSITNPLESEVADGDTEYYRVEVFLEHGGQHYDVMGFTQDQILADVVTQYEK
YLHYLHLSSSEYLGSEAN
>Mature_657_residues
SIKSSINPPVFFSSVILITLMVVVCAVWPTQSQDIFKTAQSWFELKAGWLYILGVAIFLIFIIFVMVSRFGDIKLGPDHA
EPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMAPPDADPLTIQAAKDAMKITFFHWGIHAWAIYAVVALSLAYFSYR
HKLPLLPRSALYPLIGDKIYGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLDVPVNTTVQVGLIIGVCLIATV
SVFSGLDKGVKRLSELNLFLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNLYAYEQKNDWIGGWTLLYWGWW
ISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWMTGFGNSAIDVIANGGTYLSDAVSSDVSVALFVFFEHLPFST
LLSTIALCLVVTFFVTSSDSGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVML
LMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKVAQPALSKVCESFLSRSISAEI
LNFDNRVRFVVPSEDHNDFVYGLRTRGFSITNPLESEVADGDTEYYRVEVFLEHGGQHYDVMGFTQDQILADVVTQYEKY
LHYLHLSSSEYLGSEAN

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=655, Percent_Identity=38.6259541984733, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1786224, Length=504, Percent_Identity=26.5873015873016, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788102, Length=456, Percent_Identity=29.3859649122807, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 72796; Mature: 72665

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSSINPPVFFSSVILITLMVVVCAVWPTQSQDIFKTAQSWFELKAGWLYILGVAIFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFIIFVMVSRFGDIKLGPDHAEPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMAPPD
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
ADPLTIQAAKDAMKITFFHWGIHAWAIYAVVALSLAYFSYRHKLPLLPRSALYPLIGDKI
CCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHH
YGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLDVPVNTTVQVGLIIGVCLIAT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHH
VSVFSGLDKGVKRLSELNLFLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCEEE
YAYEQKNDWIGGWTLLYWGWWISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWM
EEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TGFGNSAIDVIANGGTYLSDAVSSDVSVALFVFFEHLPFSTLLSTIALCLVVTFFVTSSD
HCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
SGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVM
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LLMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKV
HHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHH
AQPALSKVCESFLSRSISAEILNFDNRVRFVVPSEDHNDFVYGLRTRGFSITNPLESEVA
HHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHC
DGDTEYYRVEVFLEHGGQHYDVMGFTQDQILADVVTQYEKYLHYLHLSSSEYLGSEAN
CCCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure 
SIKSSINPPVFFSSVILITLMVVVCAVWPTQSQDIFKTAQSWFELKAGWLYILGVAIFL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]