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The map label for this gene is glnS [H]

Identifier: 167624693

GI number: 167624693

Start: 3367730

End: 3369400

Strand: Reverse

Name: glnS [H]

Synonym: Shal_2775

Alternate gene names: 167624693

Gene position: 3369400-3367730 (Counterclockwise)

Preceding gene: 167624694

Following gene: 167624689

Centisome position: 64.46

GC content: 43.03

Gene sequence:

>1671_bases
ATGAGTCATGTGGACACTGAAGTACGTCCTAGTAACTTCATACGTAACATCATAGATGAAGATCTAGCTACTGGTAAGCA
CACGAGTGTACAAACTCGTTTCCCGCCGGAGCCAAACGGCTTTCTTCATATCGGCCACGCTAAGTCTATCTGCCTAAACT
TTGGTATTGCAAAGGACTACAAAGGTCAATGTAACTTACGTTTTGATGATACCAATCCTGAAAAAGAAGATATCGATTAC
GTTAATTCTATTCAGGCTGATGTGCAGTGGCTCGGTTTTCAGTGGGATGGTGATATTCGTTATTCATCAAACTATTTTGA
CCAATTACACCAGTACGCAGTTGAGTTAATCACTAAAGGCTTAGCTTATGTGTGCTTCTTAAATGGTGAAGAGACTCGCG
AATATCGCGGTACGCTTAAAGAGCCAGGTAAGAACAGCCCATACCGTGACACTTCGGTCGAAGAGAACCTCGCATTATTT
GAAAAAATGCGCTTAGGCGAGTTCAAAGAAGGTGAATGTTCACTTCGCGCTAAGATTGATATGGCATCACCATTTATGTG
TATGCGTGATCCTATCATCTACCGTATTCGTTTTGCTCATCACCATCAGACAGGTGACAAGTGGTGCATTTACCCAATGT
ACGACTTTACTCACTGTATTTCTGATGCGATTGAAAATATTACCCATTCTTTATGTACGCTTGAGTTCCAAGACAACCGT
AGACTGTATGACTGGGTACTCGATCATCTTGATGATTTCCAAGCGCCAAACAGAACACGTCAGTACGAGTTTTCAAGACT
GAATCTTGAATACACCTTGATGTCAAAGCGTAAGCTTAATGACTTAGTTGTCCGTAACCTAGTAACGGGTTGGGACGATG
CGCGTATGCCTACGATTGCGGGTTACCGTCGCCGCGGCTATACACCAGCGTCTATTCGTGAATTCTGTAAGCGCATAGGT
GTGACTAAGCAAGACAACATGGTTGAAGTTGCCATGCTTGATGCTTGTATTCGCGAAGAGCTAAATGAATTCGCGCCACG
CGCAATGGCAGTGATTAACCCTGTTAAAGTGGTTATCGAAAACTATCCTGAAGGGCAAGTTGAGATCATCAACGCTGCAA
ATCATCCTAACAAGGAAGAGATGGGCAAGCGTGAATTGTCTTTTGGTCGTGAACTATTTATTGATGCTGACGATTTCCGT
GAAGAAGCAAATAAGAAGTACAAGCGTCTAGTTCAAGGTAAAGAAGTGCGTTTGCGTAATGCTTACGTGATCCAAGCCGA
GCGCTGTGAAAAAGATGCTGATGGTAATATCACTACTATTTTCTGTACTTATGATGATGAAACTTTGGGTAAAAACCCAA
GTGACGGTCGTAAAGTGAAAGGTGTTATTCATTGGGTTGAGGCGAGTACTGCAAAGCCTGCAGAGTTCCGTTTGTATGAA
AGATTATTCAACGATCCAAATCCAGCAGCTGCAGAGTCAGTTGACGAAGTGCTAAACCCGCACTCGCTAACAACTAAGTA
CGGCCTAGTTGAAGCAAGCCTGATGAATGCTGAAGCTGAAAAAGCCTATCAGTTTGAGCGTGAAGGCTACTTCTGCGCAG
ATAGCAAAGACTCAAGCAAAGATAGCTTAGTGTTTAACTTAACTGTGCCACTAAGAGATTCTTTCGAGTAA

Upstream 100 bases:

>100_bases
GCCATTAGAGAGGTTTTTAAACCTCAGTCGTTGATCCTTTACAAAATCTGTAGGATTATGCATTTTTAGTCTTTAATCAT
CGTTCGCAAAGAGGAATTCC

Downstream 100 bases:

>100_bases
ATCTTATTGAAGTACACGTTAAAACTAAAAAAGCCGACGAAAGTCGGCTTTTTTGTTACCCAAATCTAAGTTAGTTTCTG
AGTTTATTTCTGAGCTAGTC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MSHVDTEVRPSNFIRNIIDEDLATGKHTSVQTRFPPEPNGFLHIGHAKSICLNFGIAKDYKGQCNLRFDDTNPEKEDIDY
VNSIQADVQWLGFQWDGDIRYSSNYFDQLHQYAVELITKGLAYVCFLNGEETREYRGTLKEPGKNSPYRDTSVEENLALF
EKMRLGEFKEGECSLRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDAIENITHSLCTLEFQDNR
RLYDWVLDHLDDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRNLVTGWDDARMPTIAGYRRRGYTPASIREFCKRIG
VTKQDNMVEVAMLDACIREELNEFAPRAMAVINPVKVVIENYPEGQVEIINAANHPNKEEMGKRELSFGRELFIDADDFR
EEANKKYKRLVQGKEVRLRNAYVIQAERCEKDADGNITTIFCTYDDETLGKNPSDGRKVKGVIHWVEASTAKPAEFRLYE
RLFNDPNPAAAESVDEVLNPHSLTTKYGLVEASLMNAEAEKAYQFEREGYFCADSKDSSKDSLVFNLTVPLRDSFE

Sequences:

>Translated_556_residues
MSHVDTEVRPSNFIRNIIDEDLATGKHTSVQTRFPPEPNGFLHIGHAKSICLNFGIAKDYKGQCNLRFDDTNPEKEDIDY
VNSIQADVQWLGFQWDGDIRYSSNYFDQLHQYAVELITKGLAYVCFLNGEETREYRGTLKEPGKNSPYRDTSVEENLALF
EKMRLGEFKEGECSLRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDAIENITHSLCTLEFQDNR
RLYDWVLDHLDDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRNLVTGWDDARMPTIAGYRRRGYTPASIREFCKRIG
VTKQDNMVEVAMLDACIREELNEFAPRAMAVINPVKVVIENYPEGQVEIINAANHPNKEEMGKRELSFGRELFIDADDFR
EEANKKYKRLVQGKEVRLRNAYVIQAERCEKDADGNITTIFCTYDDETLGKNPSDGRKVKGVIHWVEASTAKPAEFRLYE
RLFNDPNPAAAESVDEVLNPHSLTTKYGLVEASLMNAEAEKAYQFEREGYFCADSKDSSKDSLVFNLTVPLRDSFE
>Mature_555_residues
SHVDTEVRPSNFIRNIIDEDLATGKHTSVQTRFPPEPNGFLHIGHAKSICLNFGIAKDYKGQCNLRFDDTNPEKEDIDYV
NSIQADVQWLGFQWDGDIRYSSNYFDQLHQYAVELITKGLAYVCFLNGEETREYRGTLKEPGKNSPYRDTSVEENLALFE
KMRLGEFKEGECSLRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDAIENITHSLCTLEFQDNRR
LYDWVLDHLDDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRNLVTGWDDARMPTIAGYRRRGYTPASIREFCKRIGV
TKQDNMVEVAMLDACIREELNEFAPRAMAVINPVKVVIENYPEGQVEIINAANHPNKEEMGKRELSFGRELFIDADDFRE
EANKKYKRLVQGKEVRLRNAYVIQAERCEKDADGNITTIFCTYDDETLGKNPSDGRKVKGVIHWVEASTAKPAEFRLYER
LFNDPNPAAAESVDEVLNPHSLTTKYGLVEASLMNAEAEKAYQFEREGYFCADSKDSSKDSLVFNLTVPLRDSFE

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=530, Percent_Identity=45.8490566037736, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=519, Percent_Identity=33.9113680154143, Blast_Score=272, Evalue=6e-73,
Organism=Escherichia coli, GI1786895, Length=551, Percent_Identity=72.9582577132486, Blast_Score=848, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=119, Percent_Identity=27.7310924369748, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=538, Percent_Identity=42.1933085501859, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=533, Percent_Identity=31.3320825515947, Blast_Score=227, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324742, Length=565, Percent_Identity=39.4690265486726, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321192, Length=539, Percent_Identity=34.3228200371057, Blast_Score=279, Evalue=7e-76,
Organism=Drosophila melanogaster, GI17864488, Length=547, Percent_Identity=40.7678244972578, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24649466, Length=420, Percent_Identity=38.8095238095238, Blast_Score=261, Evalue=9e-70,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64298; Mature: 64167

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVDTEVRPSNFIRNIIDEDLATGKHTSVQTRFPPEPNGFLHIGHAKSICLNFGIAKDY
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCHHEEHEECCCCCCC
KGQCNLRFDDTNPEKEDIDYVNSIQADVQWLGFQWDGDIRYSSNYFDQLHQYAVELITKG
CCCEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEECCHHHHHHHHHHHHHHHCC
LAYVCFLNGEETREYRGTLKEPGKNSPYRDTSVEENLALFEKMRLGEFKEGECSLRAKID
CEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEC
MASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDAIENITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDHLDDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRNLVTGWDDARMPTIA
CHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHH
GYRRRGYTPASIREFCKRIGVTKQDNMVEVAMLDACIREELNEFAPRAMAVINPVKVVIE
HHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NYPEGQVEIINAANHPNKEEMGKRELSFGRELFIDADDFREEANKKYKRLVQGKEVRLRN
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEC
AYVIQAERCEKDADGNITTIFCTYDDETLGKNPSDGRKVKGVIHWVEASTAKPAEFRLYE
EEEEEHHHCCCCCCCCEEEEEEEECCHHCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHH
RLFNDPNPAAAESVDEVLNPHSLTTKYGLVEASLMNAEAEKAYQFEREGYFCADSKDSSK
HHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCC
DSLVFNLTVPLRDSFE
CCEEEEEEECCCCCCC
>Mature Secondary Structure 
SHVDTEVRPSNFIRNIIDEDLATGKHTSVQTRFPPEPNGFLHIGHAKSICLNFGIAKDY
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCHHEEHEECCCCCCC
KGQCNLRFDDTNPEKEDIDYVNSIQADVQWLGFQWDGDIRYSSNYFDQLHQYAVELITKG
CCCEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEECCHHHHHHHHHHHHHHHCC
LAYVCFLNGEETREYRGTLKEPGKNSPYRDTSVEENLALFEKMRLGEFKEGECSLRAKID
CEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEC
MASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDAIENITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDHLDDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRNLVTGWDDARMPTIA
CHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHH
GYRRRGYTPASIREFCKRIGVTKQDNMVEVAMLDACIREELNEFAPRAMAVINPVKVVIE
HHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NYPEGQVEIINAANHPNKEEMGKRELSFGRELFIDADDFREEANKKYKRLVQGKEVRLRN
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEC
AYVIQAERCEKDADGNITTIFCTYDDETLGKNPSDGRKVKGVIHWVEASTAKPAEFRLYE
EEEEEHHHCCCCCCCCEEEEEEEECCHHCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHH
RLFNDPNPAAAESVDEVLNPHSLTTKYGLVEASLMNAEAEKAYQFEREGYFCADSKDSSK
HHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCC
DSLVFNLTVPLRDSFE
CCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]