Click here to switch to the map view.

The map label for this gene is aroC [H]

Identifier: 167624579

GI number: 167624579

Start: 3225163

End: 3226257

Strand: Reverse

Name: aroC [H]

Synonym: Shal_2660

Alternate gene names: 167624579

Gene position: 3226257-3225163 (Counterclockwise)

Preceding gene: 167624580

Following gene: 167624578

Centisome position: 61.72

GC content: 48.49

Gene sequence:

>1095_bases
ATGTCGGGAAACAGTATTGGTCAAAATTTCGTAGTAACAACATTCGGTGAAAGCCACGGTGTAGCCATTGGTTGCATTAT
CGACGGTTGCCCTCCAGGCGTTGAGCTGACCGAAGCGGATATGCAGCACGACTTAGATAGACGCCGGCCAGGTACGTCAC
GCTATACCACGGCTCGTCGCGAGCCAGATGAAGTGCGTATTCTTTCAGGCGTATTTGAGGGCGAAACCACAGGTACTTCA
ATTGGCTTGTTAATTGAAAATACCGATCAGCGCAGCAAAGATTACTCAAATATCAAAGATTTGTTCCGTCCAGGACATGC
CGATTACACTTATCAGCAAAAATATGGCCAGCGCGATTATCGTGGCGGCGGACGTTCATCTGCTCGTGAAACGGCAATGC
GAGTGGCAGCTGGTGCTGTCGCTAAAAAGTATTTGAAACAAGTTCACGGCGTTGAGATCCATGCGTATCTGTCACAGCTT
GGTCCTATCTCGGCCGAGACTGTCGATTTTGAACAGATAGAGCAAAATGCCTTTTTCTTCCCTGATGCATCAAAGTTAGC
GTCATTAGACGAATATATGCGCGAGCTTATAAAGAGCGGCGACTCGATTGGTGCTAAAGTTTCAGTGGTTGCAACGGGTG
TACCTGTAGGGCTTGGCGAGCCAGTTTTTGATCGCCTCGATGCCGATATCGCTCATGCGCTTATGGGCATTAATGCCGTG
AAAGGTGTTGAGATTGGCGATGGCTTTGAGGTGGTTAATCAAAAAGGTTCAGAGCACCGAGACTTGATGTCACCAGAGGG
CTTTGCGTCAAACCATGCTGGCGGTATTTTAGGCGGAATTTCATCAGGCCAACCGATTGTTGCCCATATCGCGATGAAAC
CCACTTCAAGTATTAGCGTGCCAGGCGAAAGCATGACAGCCCAAGGTGAAACCGCTGAAGTGGTTACAAAGGGTCGTCAC
GATCCTTGTGTCGGTATTCGAGCTGTACCGATTGCAGAAGCCATGCTAGCAATCGTATTGATGGATCACCTTTTACGTCA
CCGCGCGCAAAATATGGATGTGAATAGCAGTACACCTATTATCGGAATGCGTTAA

Upstream 100 bases:

>100_bases
TACATTGTGATTGATATTTAATTGGGTATAGATGAGGTATTTACCGACAAAGCGCGGGTAAATAATAATGAGAATAAAGC
GATAGAGGGCGATAAAGCGG

Downstream 100 bases:

>100_bases
TGTTTCAACCCAAAAGCACAGAGCAGCAACTGCGCTGGCTCTGTGCATGTTATTTCTTTTTCTTTTCTATTCTTGGCATT
ATGGTGCCTTATCTTGGCGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGETTGTS
IGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQL
GPISAETVDFEQIEQNAFFFPDASKLASLDEYMRELIKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
KGVEIGDGFEVVNQKGSEHRDLMSPEGFASNHAGGILGGISSGQPIVAHIAMKPTSSISVPGESMTAQGETAEVVTKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPIIGMR

Sequences:

>Translated_364_residues
MSGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGETTGTS
IGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQL
GPISAETVDFEQIEQNAFFFPDASKLASLDEYMRELIKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
KGVEIGDGFEVVNQKGSEHRDLMSPEGFASNHAGGILGGISSGQPIVAHIAMKPTSSISVPGESMTAQGETAEVVTKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPIIGMR
>Mature_363_residues
SGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGETTGTSI
GLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQLG
PISAETVDFEQIEQNAFFFPDASKLASLDEYMRELIKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAVK
GVEIGDGFEVVNQKGSEHRDLMSPEGFASNHAGGILGGISSGQPIVAHIAMKPTSSISVPGESMTAQGETAEVVTKGRHD
PCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPIIGMR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=75.4874651810585, Blast_Score=545, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=43.9024390243902, Blast_Score=294, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39024; Mature: 38892

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARR
CCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDEVRILSGVFEGETTGTSIGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQLGPISAETVDFEQIEQNAFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHCCCEEC
PDASKLASLDEYMRELIKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFEVVNQKGSEHRDLMSPEGFASNHAGGILGGISSGQPIVAHIAMKPTSSISV
CCCCCCCCHHHHHCCCCCHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCC
PGESMTAQGETAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPI
CCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IGMR
EECC
>Mature Secondary Structure 
SGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARR
CCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDEVRILSGVFEGETTGTSIGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQLGPISAETVDFEQIEQNAFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHCCCEEC
PDASKLASLDEYMRELIKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFEVVNQKGSEHRDLMSPEGFASNHAGGILGGISSGQPIVAHIAMKPTSSISV
CCCCCCCCHHHHHCCCCCHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCC
PGESMTAQGETAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPI
CCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IGMR
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA