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The map label for this gene is ushA [H]

Identifier: 167624313

GI number: 167624313

Start: 2890467

End: 2892248

Strand: Reverse

Name: ushA [H]

Synonym: Shal_2390

Alternate gene names: 167624313

Gene position: 2892248-2890467 (Counterclockwise)

Preceding gene: 167624314

Following gene: 167624312

Centisome position: 55.33

GC content: 42.37

Gene sequence:

>1782_bases
ATGAATAAGATTTTACTTAAAGGGCTAGTCGCAACAGCTGTTGTATCTGCGTTAACAGCTTGTGGCAGTGATAATAACGA
TGACCATAAGTATATCTCGCAAGCTTGTGCTGATGCGGGTGACGCTTGTACGATTTTTACTGTAATCCACACCAATGATA
ACCATGGCCGTTTCTGGGCAAATAAAGATGGCGAATATGGTATGGCGGCGCGTAAAACAGCTATCGACACTATTCGTGAT
GAAGTAGAGCGCGAAGGTGGCGAGTCTATTTTACTTTCTGGTGGTGACATTAATACGGGTGTACCAGAGTCTGATATGCA
AGATGCAGTACCAGACTTTATCGGTATGGGGATGTTAGGTTATGACGCAATGGCTGTTGGTAACCACGAATTTGATAACC
CTCTATCAGTATTAGATATGCAAGCTAATATTGCTAAATTTCCAATGCTAGCTGCAAACATTTACAAAAAAGATAGCGAA
GGAAAACCTACAGCGGAGCGTTACTTTGAACCTTACCGTGTTTTTGAAATCAACGGGTTAAAGGTTGCTGTCATAGGTTT
CACTACTGTTGATACACCAAAAGTTGTCAGCCCAGACAATGTAGAAAGCCTGCATTTCACCGATCCTCAGGTTGAGATTG
AAAAAGTACTAACTGAAATCGAAACAAACGAAACCGTAGATATGGTGTTCGCGCTAACGCACATGGGTCATTATGCAAAT
GGTGAGCACGGTACTGAAGCTCCAGGCGATGTAAAGTTAGCTGAATCGGTTGCCAAAGGTAAGTTACAAGCCATTATTGG
TGGTCACTCACAAAACCCAGTTTGTATGGAAGGTGATGGCTACGCAGATTTTAAACCTGGTGATGAATGCAAGCCTGATC
AGAAAAATGGTACTTATATCATGCAAGCTCACGAATGGGGCAAGTATGTTGGCCGCGCTGATTTTGAATATATCAATGGC
GAATTGACATTAGCTAGCTATAAGCTGATCCCTATCAACTTAAAAGAAGAAAATGAAAACGAAGAACTTGTTTTCATTAC
TGAAGAGATTGAACAAGATCAGTTGGTAATTGATGCGCTGCAGCATTATCAAGATATTGGTCAAGAGCTACTTGATGTGG
ATATTTCAAGTACAGATGGCAAGCTTGAAGGTGACCGCGGTGTTGTTCGTGCTGAACAAACTAACCTAGGTCAACTATTA
ACTCGCGCTTACGCTGATTGGGTTACTGCTAACTTCGCTGCGACTGTAGACTTTGGTGTGATGAACTCTGGTGGTATCCG
AGATTCTATCGCTGAAGGTACAATTTCATACCGTGACGTTCTTACTGTACAACCATTTGCCAATGATGTTGCATTTGTGA
CTATGTCTGGTACCGAAGTACAAGATTACCTAGCGAATGTAGCGGTAAAGACTGGTGGTGGTATGCCTCAGCTTTATCCA
ATGGAAATGAACGTGGCTTGTGATGCTCTTGAAATTAATCCAGAGGCAACTTCTGCTGACATCGTAGATATAGCATCTCT
AGGTGGCCGAGATTTCAATCCTAACGATAATTACACTTTCTCATTGATTAATTTCAGTGCTAAAGGTGGTGATGACTACC
CAGTAGTGACAGCTCATGCAAACTACATTGATACGCAACGTAGCGATGCATCAGTACTTCGTGAATACTTCGAGAAGAAC
CCAAGCATTAAGGTAGCTGAATACGCGCCTGCTAATGGTGGTCACCCTAAATTCTTCCGTGGTGGCTCAGAAGTTAAGAG
CTGTGCTAAAGCTGCTGATTAA

Upstream 100 bases:

>100_bases
TAAGCTTTGATAAGATGGCTTCCGCAAAAGGAAATGATGCTTTTTGCTAGATAACTTTAAAGTTACAAAATATAAAAAAT
ATATCAAGGGGTTGATTGTA

Downstream 100 bases:

>100_bases
TCGTTATTAGCCCAACTGAATCGTTTAAATTTGATTATTCGAGTTTAACGATTTAGCAGACAAAGACGTTGTATTTTTAA
AATCCAGTACTTGCTTTTGC

Product: bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MNKILLKGLVATAVVSALTACGSDNNDDHKYISQACADAGDACTIFTVIHTNDNHGRFWANKDGEYGMAARKTAIDTIRD
EVEREGGESILLSGGDINTGVPESDMQDAVPDFIGMGMLGYDAMAVGNHEFDNPLSVLDMQANIAKFPMLAANIYKKDSE
GKPTAERYFEPYRVFEINGLKVAVIGFTTVDTPKVVSPDNVESLHFTDPQVEIEKVLTEIETNETVDMVFALTHMGHYAN
GEHGTEAPGDVKLAESVAKGKLQAIIGGHSQNPVCMEGDGYADFKPGDECKPDQKNGTYIMQAHEWGKYVGRADFEYING
ELTLASYKLIPINLKEENENEELVFITEEIEQDQLVIDALQHYQDIGQELLDVDISSTDGKLEGDRGVVRAEQTNLGQLL
TRAYADWVTANFAATVDFGVMNSGGIRDSIAEGTISYRDVLTVQPFANDVAFVTMSGTEVQDYLANVAVKTGGGMPQLYP
MEMNVACDALEINPEATSADIVDIASLGGRDFNPNDNYTFSLINFSAKGGDDYPVVTAHANYIDTQRSDASVLREYFEKN
PSIKVAEYAPANGGHPKFFRGGSEVKSCAKAAD

Sequences:

>Translated_593_residues
MNKILLKGLVATAVVSALTACGSDNNDDHKYISQACADAGDACTIFTVIHTNDNHGRFWANKDGEYGMAARKTAIDTIRD
EVEREGGESILLSGGDINTGVPESDMQDAVPDFIGMGMLGYDAMAVGNHEFDNPLSVLDMQANIAKFPMLAANIYKKDSE
GKPTAERYFEPYRVFEINGLKVAVIGFTTVDTPKVVSPDNVESLHFTDPQVEIEKVLTEIETNETVDMVFALTHMGHYAN
GEHGTEAPGDVKLAESVAKGKLQAIIGGHSQNPVCMEGDGYADFKPGDECKPDQKNGTYIMQAHEWGKYVGRADFEYING
ELTLASYKLIPINLKEENENEELVFITEEIEQDQLVIDALQHYQDIGQELLDVDISSTDGKLEGDRGVVRAEQTNLGQLL
TRAYADWVTANFAATVDFGVMNSGGIRDSIAEGTISYRDVLTVQPFANDVAFVTMSGTEVQDYLANVAVKTGGGMPQLYP
MEMNVACDALEINPEATSADIVDIASLGGRDFNPNDNYTFSLINFSAKGGDDYPVVTAHANYIDTQRSDASVLREYFEKN
PSIKVAEYAPANGGHPKFFRGGSEVKSCAKAAD
>Mature_593_residues
MNKILLKGLVATAVVSALTACGSDNNDDHKYISQACADAGDACTIFTVIHTNDNHGRFWANKDGEYGMAARKTAIDTIRD
EVEREGGESILLSGGDINTGVPESDMQDAVPDFIGMGMLGYDAMAVGNHEFDNPLSVLDMQANIAKFPMLAANIYKKDSE
GKPTAERYFEPYRVFEINGLKVAVIGFTTVDTPKVVSPDNVESLHFTDPQVEIEKVLTEIETNETVDMVFALTHMGHYAN
GEHGTEAPGDVKLAESVAKGKLQAIIGGHSQNPVCMEGDGYADFKPGDECKPDQKNGTYIMQAHEWGKYVGRADFEYING
ELTLASYKLIPINLKEENENEELVFITEEIEQDQLVIDALQHYQDIGQELLDVDISSTDGKLEGDRGVVRAEQTNLGQLL
TRAYADWVTANFAATVDFGVMNSGGIRDSIAEGTISYRDVLTVQPFANDVAFVTMSGTEVQDYLANVAVKTGGGMPQLYP
MEMNVACDALEINPEATSADIVDIASLGGRDFNPNDNYTFSLINFSAKGGDDYPVVTAHANYIDTQRSDASVLREYFEKN
PSIKVAEYAPANGGHPKFFRGGSEVKSCAKAAD

Specific function: Degradation of extracellular 5'-nucleotides for nutritional needs [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=570, Percent_Identity=24.5614035087719, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1786687, Length=575, Percent_Identity=47.4782608695652, Blast_Score=507, Evalue=1e-145,
Organism=Drosophila melanogaster, GI19922446, Length=554, Percent_Identity=25.0902527075812, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24654424, Length=554, Percent_Identity=25.0902527075812, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19922444, Length=559, Percent_Identity=24.5080500894454, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28573524, Length=455, Percent_Identity=26.5934065934066, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641187, Length=435, Percent_Identity=22.2988505747126, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 64447; Mature: 64447

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKILLKGLVATAVVSALTACGSDNNDDHKYISQACADAGDACTIFTVIHTNDNHGRFWA
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEE
NKDGEYGMAARKTAIDTIRDEVEREGGESILLSGGDINTGVPESDMQDAVPDFIGMGMLG
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHC
YDAMAVGNHEFDNPLSVLDMQANIAKFPMLAANIYKKDSEGKPTAERYFEPYRVFEINGL
CCEEEECCCCCCCCHHEEECHHHHHHCCHHHHHHHCCCCCCCCCHHHHCCCEEEEEECCE
KVAVIGFTTVDTPKVVSPDNVESLHFTDPQVEIEKVLTEIETNETVDMVFALTHMGHYAN
EEEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GEHGTEAPGDVKLAESVAKGKLQAIIGGHSQNPVCMEGDGYADFKPGDECKPDQKNGTYI
CCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEE
MQAHEWGKYVGRADFEYINGELTLASYKLIPINLKEENENEELVFITEEIEQDQLVIDAL
EEECHHHHHCCCCCEEEECCEEEEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHH
QHYQDIGQELLDVDISSTDGKLEGDRGVVRAEQTNLGQLLTRAYADWVTANFAATVDFGV
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEEC
MNSGGIRDSIAEGTISYRDVLTVQPFANDVAFVTMSGTEVQDYLANVAVKTGGGMPQLYP
CCCCCCCHHHHCCCEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHEEEECCCCCCEEEE
MEMNVACDALEINPEATSADIVDIASLGGRDFNPNDNYTFSLINFSAKGGDDYPVVTAHA
EEECEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEC
NYIDTQRSDASVLREYFEKNPSIKVAEYAPANGGHPKFFRGGSEVKSCAKAAD
CCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNKILLKGLVATAVVSALTACGSDNNDDHKYISQACADAGDACTIFTVIHTNDNHGRFWA
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEE
NKDGEYGMAARKTAIDTIRDEVEREGGESILLSGGDINTGVPESDMQDAVPDFIGMGMLG
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHC
YDAMAVGNHEFDNPLSVLDMQANIAKFPMLAANIYKKDSEGKPTAERYFEPYRVFEINGL
CCEEEECCCCCCCCHHEEECHHHHHHCCHHHHHHHCCCCCCCCCHHHHCCCEEEEEECCE
KVAVIGFTTVDTPKVVSPDNVESLHFTDPQVEIEKVLTEIETNETVDMVFALTHMGHYAN
EEEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GEHGTEAPGDVKLAESVAKGKLQAIIGGHSQNPVCMEGDGYADFKPGDECKPDQKNGTYI
CCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEE
MQAHEWGKYVGRADFEYINGELTLASYKLIPINLKEENENEELVFITEEIEQDQLVIDAL
EEECHHHHHCCCCCEEEECCEEEEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHH
QHYQDIGQELLDVDISSTDGKLEGDRGVVRAEQTNLGQLLTRAYADWVTANFAATVDFGV
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEEC
MNSGGIRDSIAEGTISYRDVLTVQPFANDVAFVTMSGTEVQDYLANVAVKTGGGMPQLYP
CCCCCCCHHHHCCCEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHEEEECCCCCCEEEE
MEMNVACDALEINPEATSADIVDIASLGGRDFNPNDNYTFSLINFSAKGGDDYPVVTAHA
EEECEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEC
NYIDTQRSDASVLREYFEKNPSIKVAEYAPANGGHPKFFRGGSEVKSCAKAAD
CCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2016269; 12620739 [H]