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The map label for this gene is hda [H]

Identifier: 167624256

GI number: 167624256

Start: 2817420

End: 2818130

Strand: Reverse

Name: hda [H]

Synonym: Shal_2332

Alternate gene names: 167624256

Gene position: 2818130-2817420 (Counterclockwise)

Preceding gene: 167624257

Following gene: 167624251

Centisome position: 53.92

GC content: 44.59

Gene sequence:

>711_bases
GTGAAGTCAAACTCTCCTTTACAGTTATCATTACCAGTTCATCTACCTGATGATGAAACCTTCAATAGTTATTATCCGGC
AGCGGGTAATGATGAGCTTATTCAAAGTTTACAAGCTTGTGCCGAGGGTAGAGCAGAAGGTGCAGTATTTTTATGGGGTC
CAGAAAAGTCTGGACGTACCCACCTTATGCATGCCGCCTGTGCTCACGCGAATGATCTTGGGCGTAGCAGCTTCTATATT
CCTTTAGGGATCCATGCGAGTATTTCTACAGCGTTATTAGAAGGCTTAGAGAAACTCGACCTCGTCTGTATTGATGATGT
CAATGCCATTGCAGGGCACCCCTTATGGGAAGAAGCGATATTTGATCTTTACAATCGAATTTCTGAGCAGAAGACTTGCT
CGCTTATTGTCAGTGCGAGTGTCTCGCCAAGTGATAGTGGTTTCTCTTTACCGGATTTAGTCTCTCGAATGCAATGGGGG
CTTAATTATCAGCTACAACCCATGGCTGATGAAGAAAAACTTGCGGCACTGCAACGCCGTGCGGCGATGAGAGGCTTACA
GTTGCCAGAAGATGTAGGTCGCTTTCTATTAAACCGCTTAGCAAGAGACTTAAGAACACTATTTGACGTGTTAGATAGGC
TCGATAAAGCCTCTATGGTTCACCAACGTAAGCTGACAATCCCTTTTATTAAAGAGATGCTGCGACTGTAA

Upstream 100 bases:

>100_bases
CAGATCTATTATTGGAAAGGTCAATAGCTCCCAATCAATTGACACACATGCTACCATGTGTGTCTAATATAGATATATTG
CGTCGTTGAGAAGCACCTGA

Downstream 100 bases:

>100_bases
GTACTTTGATAATTATATAAGATAAAAGCCCAGATATTCATCTGGGCTTTTGCGTTTTCAGAGTCGAGAAAGTTTACGAT
TAATCGACAGGTTTTACGTG

Product: DNA replication initiation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKSNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQSLQACAEGRAEGAVFLWGPEKSGRTHLMHAACAHANDLGRSSFYI
PLGIHASISTALLEGLEKLDLVCIDDVNAIAGHPLWEEAIFDLYNRISEQKTCSLIVSASVSPSDSGFSLPDLVSRMQWG
LNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL

Sequences:

>Translated_236_residues
MKSNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQSLQACAEGRAEGAVFLWGPEKSGRTHLMHAACAHANDLGRSSFYI
PLGIHASISTALLEGLEKLDLVCIDDVNAIAGHPLWEEAIFDLYNRISEQKTCSLIVSASVSPSDSGFSLPDLVSRMQWG
LNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL
>Mature_236_residues
MKSNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQSLQACAEGRAEGAVFLWGPEKSGRTHLMHAACAHANDLGRSSFYI
PLGIHASISTALLEGLEKLDLVCIDDVNAIAGHPLWEEAIFDLYNRISEQKTCSLIVSASVSPSDSGFSLPDLVSRMQWG
LNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=233, Percent_Identity=52.3605150214592, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI2367267, Length=229, Percent_Identity=24.8908296943231, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 26272; Mature: 26272

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQSLQACAEGRAEGAVFLWGPEKSGRT
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
HLMHAACAHANDLGRSSFYIPLGIHASISTALLEGLEKLDLVCIDDVNAIAGHPLWEEAI
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEECCCHHHHCCCHHHHHH
FDLYNRISEQKTCSLIVSASVSPSDSGFSLPDLVSRMQWGLNYQLQPMADEEKLAALQRR
HHHHHHHCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
AAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MKSNSPLQLSLPVHLPDDETFNSYYPAAGNDELIQSLQACAEGRAEGAVFLWGPEKSGRT
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
HLMHAACAHANDLGRSSFYIPLGIHASISTALLEGLEKLDLVCIDDVNAIAGHPLWEEAI
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEECCCHHHHCCCHHHHHH
FDLYNRISEQKTCSLIVSASVSPSDSGFSLPDLVSRMQWGLNYQLQPMADEEKLAALQRR
HHHHHHHCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
AAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA