Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 167624245

GI number: 167624245

Start: 2807423

End: 2808307

Strand: Reverse

Name: dapA [H]

Synonym: Shal_2321

Alternate gene names: 167624245

Gene position: 2808307-2807423 (Counterclockwise)

Preceding gene: 167624248

Following gene: 167624244

Centisome position: 53.73

GC content: 44.52

Gene sequence:

>885_bases
ATGATATACGGAAGCATCGTTGCCTTAATCACACCAATGAATAGTGATGGCACAGTAGATTATAAGAGTCTTGAAAGTTT
AGTTGAGTACCATATCGCCCAAGGTACAGATGCCATTGTTGCCGTTGGCACAACCGGTGAGTCTGCAACACTGCCTGCGA
AAGAGCATATTGCTGTTGTCGAACAAACGGTAAAATTTGCAGCGGGTCGAATCCCAATTATTGGTGGGAATGGCGCTAAC
GCAACGGCAGAAGCGATTGAGTTAACTAAAGGCCTCACAAATACAGGTGTGGCTGCAATGCTAGGTGTTACACCTTATTA
CAACAAGCCAACACCAAAGGGGCTTATTGCACACTATAGCGCTGTTGCAGCGAGTACCGATGTACCACAAATCCTATATA
ACGTACCAGGACGCACCGCTGTCGACATGCTGCCAGAAACCGTAGCTCAACTCGTCGGTGTAAAAAACATTATCGGTGTT
AAAGAAGCGACTGGCGATCTGTCTAGGGTTAAAGAGTTACGTCGTTTATGTGGCGATGATTTCTTGCTGTATAGTGGCGA
TGATGCAACAGCAAGAGAGTTCCTAACACTTGGTGGCAATGGCGTTATTTCTGTTGCGAACAATATTGTTCCAAAACAGT
TTAAAGCTATGTGTGACGCTGCGCTAGCGGGTAATATTCCTGCTGCATTAGCTGCTGAAGAGTCGATTAAAGAATTATTT
AGCGTACTGTTCTGTGAAGCCAATCCTATCCCAGTAAAATGGGCTGCTCACCGAATGGGACTGATTAGTAGAGGTGATAT
TCGTTTACCTTTAACTGAACTTTCTACAGAGTTTCATGGTCTGTTGCTAGAAGCGATGAAAAATGCCCGAATCGAGGTTG
AATAA

Upstream 100 bases:

>100_bases
TCAAGTTGATGATGAATATGCTTAAGTCTTGCGTTGTAGTGCTTGTTTTTAGTGGATTGCATCAGTACCATAGCCAGTCC
TGAACCCTTGGGGAATACAC

Downstream 100 bases:

>100_bases
TAAATGCTAAAGCAAATATCTCCACTTATTTTAGTTGCAGCTGTTACTGCATGTAGTACGCCAATTGACAGAAGACAGGC
TAATGACACGGATCAGAACT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MIYGSIVALITPMNSDGTVDYKSLESLVEYHIAQGTDAIVAVGTTGESATLPAKEHIAVVEQTVKFAAGRIPIIGGNGAN
ATAEAIELTKGLTNTGVAAMLGVTPYYNKPTPKGLIAHYSAVAASTDVPQILYNVPGRTAVDMLPETVAQLVGVKNIIGV
KEATGDLSRVKELRRLCGDDFLLYSGDDATAREFLTLGGNGVISVANNIVPKQFKAMCDAALAGNIPAALAAEESIKELF
SVLFCEANPIPVKWAAHRMGLISRGDIRLPLTELSTEFHGLLLEAMKNARIEVE

Sequences:

>Translated_294_residues
MIYGSIVALITPMNSDGTVDYKSLESLVEYHIAQGTDAIVAVGTTGESATLPAKEHIAVVEQTVKFAAGRIPIIGGNGAN
ATAEAIELTKGLTNTGVAAMLGVTPYYNKPTPKGLIAHYSAVAASTDVPQILYNVPGRTAVDMLPETVAQLVGVKNIIGV
KEATGDLSRVKELRRLCGDDFLLYSGDDATAREFLTLGGNGVISVANNIVPKQFKAMCDAALAGNIPAALAAEESIKELF
SVLFCEANPIPVKWAAHRMGLISRGDIRLPLTELSTEFHGLLLEAMKNARIEVE
>Mature_294_residues
MIYGSIVALITPMNSDGTVDYKSLESLVEYHIAQGTDAIVAVGTTGESATLPAKEHIAVVEQTVKFAAGRIPIIGGNGAN
ATAEAIELTKGLTNTGVAAMLGVTPYYNKPTPKGLIAHYSAVAASTDVPQILYNVPGRTAVDMLPETVAQLVGVKNIIGV
KEATGDLSRVKELRRLCGDDFLLYSGDDATAREFLTLGGNGVISVANNIVPKQFKAMCDAALAGNIPAALAAEESIKELF
SVLFCEANPIPVKWAAHRMGLISRGDIRLPLTELSTEFHGLLLEAMKNARIEVE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=218, Percent_Identity=27.5229357798165, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI13540533, Length=291, Percent_Identity=25.4295532646048, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=51.5570934256055, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI87082415, Length=279, Percent_Identity=27.5985663082437, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789620, Length=276, Percent_Identity=27.536231884058, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786463, Length=243, Percent_Identity=26.7489711934156, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31033; Mature: 31033

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGSIVALITPMNSDGTVDYKSLESLVEYHIAQGTDAIVAVGTTGESATLPAKEHIAVV
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
EQTVKFAAGRIPIIGGNGANATAEAIELTKGLTNTGVAAMLGVTPYYNKPTPKGLIAHYS
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHH
AVAASTDVPQILYNVPGRTAVDMLPETVAQLVGVKNIIGVKEATGDLSRVKELRRLCGDD
HHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCC
FLLYSGDDATAREFLTLGGNGVISVANNIVPKQFKAMCDAALAGNIPAALAAEESIKELF
EEEECCCCHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SVLFCEANPIPVKWAAHRMGLISRGDIRLPLTELSTEFHGLLLEAMKNARIEVE
HHHHCCCCCCCEEHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MIYGSIVALITPMNSDGTVDYKSLESLVEYHIAQGTDAIVAVGTTGESATLPAKEHIAVV
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
EQTVKFAAGRIPIIGGNGANATAEAIELTKGLTNTGVAAMLGVTPYYNKPTPKGLIAHYS
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHH
AVAASTDVPQILYNVPGRTAVDMLPETVAQLVGVKNIIGVKEATGDLSRVKELRRLCGDD
HHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCC
FLLYSGDDATAREFLTLGGNGVISVANNIVPKQFKAMCDAALAGNIPAALAAEESIKELF
EEEECCCCHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SVLFCEANPIPVKWAAHRMGLISRGDIRLPLTELSTEFHGLLLEAMKNARIEVE
HHHHCCCCCCCEEHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA