Click here to switch to the map view.

The map label for this gene is hypA

Identifier: 167624195

GI number: 167624195

Start: 2754880

End: 2755227

Strand: Direct

Name: hypA

Synonym: Shal_2271

Alternate gene names: 167624195

Gene position: 2754880-2755227 (Clockwise)

Preceding gene: 167624194

Following gene: 167624212

Centisome position: 52.71

GC content: 45.98

Gene sequence:

>348_bases
GTGCATGAGTACTCGATAGTAACCGCATTGATTGAAGAGTGTGAGCGTCATGCCTTTGCTAACAATGCAAGTAAGGTGAG
CCGAGTAGAGATAAAGCTTGGGATCCTTAGTGGCGTTGAGCCAGAGTTACTCAGGACGGCTTTTGAAACCTTTAAGTTAG
AGGGGATCTGTCGCGAAGCTAATCTCGTGATGAATATCCAGCCATTAGTACTCAGATGTTTGGACTGTGGACAAAGCACA
GAACATAGTGAGCGAAGCGTAATTTGCAGCCATTGCCAAAGTGGCCAGACGAAAGTACTCGATGGTGAAGATATGATGTT
AATGCAACTCGAGCTAGAGCAAGCCTAG

Upstream 100 bases:

>100_bases
TAAACGAGAACCGAAAAGGCAAAGTGGTACTCAACACTCCTTGGGGAAGCACTCGTTACTTGGATTTACCTCAGGGTGAA
TTACTACCGAGGATCTGCTA

Downstream 100 bases:

>100_bases
TGACTATAACGGAATAAGCCCTACTATTCATATTGTAGGGCCTATTATTGTTGTTTCTAATAATATCGTTTCTAGATTAT
TAAGCTTATTATCGCAGCGC

Product: hydrogenase expression/synthesis HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MHEYSIVTALIEECERHAFANNASKVSRVEIKLGILSGVEPELLRTAFETFKLEGICREANLVMNIQPLVLRCLDCGQST
EHSERSVICSHCQSGQTKVLDGEDMMLMQLELEQA

Sequences:

>Translated_115_residues
MHEYSIVTALIEECERHAFANNASKVSRVEIKLGILSGVEPELLRTAFETFKLEGICREANLVMNIQPLVLRCLDCGQST
EHSERSVICSHCQSGQTKVLDGEDMMLMQLELEQA
>Mature_115_residues
MHEYSIVTALIEECERHAFANNASKVSRVEIKLGILSGVEPELLRTAFETFKLEGICREANLVMNIQPLVLRCLDCGQST
EHSERSVICSHCQSGQTKVLDGEDMMLMQLELEQA

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_SHEHH (B0TVE5)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674489.1
- GeneID:   5903880
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2271
- HOGENOM:   HBG688671
- OMA:   AFETFKL
- ProtClustDB:   CLSK2401670
- BioCyc:   SHAL458817:SHAL_2271-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12896; Mature: 12896

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEYSIVTALIEECERHAFANNASKVSRVEIKLGILSGVEPELLRTAFETFKLEGICREA
CCCHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
NLVMNIQPLVLRCLDCGQSTEHSERSVICSHCQSGQTKVLDGEDMMLMQLELEQA
CEEEECHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEEEEECCC
>Mature Secondary Structure
MHEYSIVTALIEECERHAFANNASKVSRVEIKLGILSGVEPELLRTAFETFKLEGICREA
CCCHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
NLVMNIQPLVLRCLDCGQSTEHSERSVICSHCQSGQTKVLDGEDMMLMQLELEQA
CEEEECHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA