Click here to switch to the map view.

The map label for this gene is cpxR [H]

Identifier: 167624144

GI number: 167624144

Start: 2685041

End: 2685724

Strand: Reverse

Name: cpxR [H]

Synonym: Shal_2220

Alternate gene names: 167624144

Gene position: 2685724-2685041 (Counterclockwise)

Preceding gene: 167624145

Following gene: 167624142

Centisome position: 51.38

GC content: 38.6

Gene sequence:

>684_bases
ATGAAACACCTTTTATTGATAGATGATGATCTTGTACTCCAGAGCAGCTTGTTACCTGTATTAGAGCGAGAAGGCTTTTT
TGTCACCGTTACAAATAGCGGCGCCGATACTCTTGATAAGCTAAAGTCCACCAGATTAGATTTGATTTTACTAGATATTA
ATTTGGCGGAGCTAAGTGGTATTGAGTTGTTAAGACAGCGGGTAAACAAGACACCGATTATCGTTATCTCAACATTAGAG
AAAGAAGAAGACAGGATTAAAATATACGAGCTGGGTGCAGATGACTTTTTGAGTAAGCCGTTTGGTTTCCGTGAACTTGT
GGTTCGAATTAATGCATTAAAGCGACGAATAGAAGCCATAAGAAATGATACAGAGTTTACTCATCAACCCTCTCAAGATA
TCAGCTTTGATGATAATCAGTGCATCATTTCAATTTCGGAACAAGCGGTGTCGTTCACTCAAACCGAATTTAAGCTGTTT
AAGTATCTATTTGAAAGAAAGGGTCAGGTCGTGACAAAGCAGGAGTTACAGCTTAGGGTTTTACAAAAAGAGTTAGGCCA
GTTTGATCGTAATCTTGATATGCATATCAGCAACACTCGGCGTAAGTTATTCGAACAACATTTGCCTAAGACCCTAATTA
ATACTGTAAGAGGTAAGGGCTATAGCTTCGCCTATGCTAATTAA

Upstream 100 bases:

>100_bases
GGATGGGTAAAAATTTTTACTTGTGCGTGAAAGCGTCTAGTAAACTTAACTCACTTACTGTAATCTAAATGAAAATGATT
CGCATTGAGTTTGATTTGAG

Downstream 100 bases:

>100_bases
TACCAATCAGTATAAGAAGTTGATCTACTCAGAGCGTTTTTGGCAAACTAATTCAAGGCGAATAGCTGAAAGAATGGTTA
TTCCCTTGTGAAGCTGTTCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKHLLLIDDDLVLQSSLLPVLEREGFFVTVTNSGADTLDKLKSTRLDLILLDINLAELSGIELLRQRVNKTPIIVISTLE
KEEDRIKIYELGADDFLSKPFGFRELVVRINALKRRIEAIRNDTEFTHQPSQDISFDDNQCIISISEQAVSFTQTEFKLF
KYLFERKGQVVTKQELQLRVLQKELGQFDRNLDMHISNTRRKLFEQHLPKTLINTVRGKGYSFAYAN

Sequences:

>Translated_227_residues
MKHLLLIDDDLVLQSSLLPVLEREGFFVTVTNSGADTLDKLKSTRLDLILLDINLAELSGIELLRQRVNKTPIIVISTLE
KEEDRIKIYELGADDFLSKPFGFRELVVRINALKRRIEAIRNDTEFTHQPSQDISFDDNQCIISISEQAVSFTQTEFKLF
KYLFERKGQVVTKQELQLRVLQKELGQFDRNLDMHISNTRRKLFEQHLPKTLINTVRGKGYSFAYAN
>Mature_227_residues
MKHLLLIDDDLVLQSSLLPVLEREGFFVTVTNSGADTLDKLKSTRLDLILLDINLAELSGIELLRQRVNKTPIIVISTLE
KEEDRIKIYELGADDFLSKPFGFRELVVRINALKRRIEAIRNDTEFTHQPSQDISFDDNQCIISISEQAVSFTQTEFKLF
KYLFERKGQVVTKQELQLRVLQKELGQFDRNLDMHISNTRRKLFEQHLPKTLINTVRGKGYSFAYAN

Specific function: Member of a two-component regulatory system [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=38.1974248927039, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=31.304347826087, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=30.8695652173913, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=30.316742081448, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.7596566523605, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.0884955752212, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=26.8398268398268, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=30.3418803418803, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=28.3783783783784, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=25.4464285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=26.9058295964126, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=27.2321428571429, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=24.3589743589744, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26301; Mature: 26301

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLLLIDDDLVLQSSLLPVLEREGFFVTVTNSGADTLDKLKSTRLDLILLDINLAELSG
CCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCEEEEEEECCHHHHHH
IELLRQRVNKTPIIVISTLEKEEDRIKIYELGADDFLSKPFGFRELVVRINALKRRIEAI
HHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHH
RNDTEFTHQPSQDISFDDNQCIISISEQAVSFTQTEFKLFKYLFERKGQVVTKQELQLRV
HCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
LQKELGQFDRNLDMHISNTRRKLFEQHLPKTLINTVRGKGYSFAYAN
HHHHHHHHHCCCCEEECHHHHHHHHHHCCHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MKHLLLIDDDLVLQSSLLPVLEREGFFVTVTNSGADTLDKLKSTRLDLILLDINLAELSG
CCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCEEEEEEECCHHHHHH
IELLRQRVNKTPIIVISTLEKEEDRIKIYELGADDFLSKPFGFRELVVRINALKRRIEAI
HHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHH
RNDTEFTHQPSQDISFDDNQCIISISEQAVSFTQTEFKLFKYLFERKGQVVTKQELQLRV
HCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
LQKELGQFDRNLDMHISNTRRKLFEQHLPKTLINTVRGKGYSFAYAN
HHHHHHHHHCCCCEEECHHHHHHHHHHCCHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]