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The map label for this gene is lolA

Identifier: 167624140

GI number: 167624140

Start: 2679423

End: 2680049

Strand: Reverse

Name: lolA

Synonym: Shal_2216

Alternate gene names: 167624140

Gene position: 2680049-2679423 (Counterclockwise)

Preceding gene: 167624141

Following gene: 167624139

Centisome position: 51.27

GC content: 41.15

Gene sequence:

>627_bases
ATGAAAAAGATTTTTGCTATTGCAGCCCTGAGCTTGCCTTTGTTTAGTCATTTCCCAGCATTTGCTGGTGCCTCAGACGA
GCTAAAAGTGAAGCTGACCGAAATAAGCAGCCTAAAAGCTAACTTTAATCAAACCGTTACAGACATCAATGATAAGGTGA
TTCAAACGGGCGAAGGAGTTTTTGCTTTGTCTCATCCTAATCAATTTTACTGGCATTTAACCGCTCCCGATGAGTCGTTA
ATCGTTGCTGACGGTACCGATGTTTGGATCTACAATCCGTTTGCCGAAGAGGTCTCTGTTATGGACCTCAATCAGGCCAT
TAATGCTTCTCCAATCGCGTTATTAGTTCACTCAGACGATGAAACCTGGTCACAATACAATGTTAGCCAAAAAGAAAACT
GTTTCGATATCAGCCCCAAAGATAAAGACAGTGGCGGATCTGAAGTGCAAGTTTGCTTTAATGATAATCAGCTAACAAAA
ATGGTGCTTAAGGATCAACAAGGCAATATCAGTGACTTCACGCTAACGAATCAAAGTGTGATAGCCGGTAAAGACCAAGA
TCTGTTTAAGTTCGTCGTACCCGATGATGTAGATATCGACGATCAACGTTTAAAATCGACCAATTAA

Upstream 100 bases:

>100_bases
CGCCACCGCCAAAAGACTACGTCTAATTAACGAATAAGTGTACTGACCCACAGAATATATTCAGTGTTAAGCCTAGAGTA
GGCTTAACTCGGAGAACAAA

Downstream 100 bases:

>100_bases
GAGAAGTCAGTGTCTAGTTTCAGTTTTGATTTTGCACCAGACTTTAGACCGTTAGCCGCACGAATGCGGCCCGAACGGCT
AGAGCAATATATTGGCCAGT

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKIFAIAALSLPLFSHFPAFAGASDELKVKLTEISSLKANFNQTVTDINDKVIQTGEGVFALSHPNQFYWHLTAPDESL
IVADGTDVWIYNPFAEEVSVMDLNQAINASPIALLVHSDDETWSQYNVSQKENCFDISPKDKDSGGSEVQVCFNDNQLTK
MVLKDQQGNISDFTLTNQSVIAGKDQDLFKFVVPDDVDIDDQRLKSTN

Sequences:

>Translated_208_residues
MKKIFAIAALSLPLFSHFPAFAGASDELKVKLTEISSLKANFNQTVTDINDKVIQTGEGVFALSHPNQFYWHLTAPDESL
IVADGTDVWIYNPFAEEVSVMDLNQAINASPIALLVHSDDETWSQYNVSQKENCFDISPKDKDSGGSEVQVCFNDNQLTK
MVLKDQQGNISDFTLTNQSVIAGKDQDLFKFVVPDDVDIDDQRLKSTN
>Mature_208_residues
MKKIFAIAALSLPLFSHFPAFAGASDELKVKLTEISSLKANFNQTVTDINDKVIQTGEGVFALSHPNQFYWHLTAPDESL
IVADGTDVWIYNPFAEEVSVMDLNQAINASPIALLVHSDDETWSQYNVSQKENCFDISPKDKDSGGSEVQVCFNDNQLTK
MVLKDQQGNISDFTLTNQSVIAGKDQDLFKFVVPDDVDIDDQRLKSTN

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=206, Percent_Identity=35.4368932038835, Blast_Score=120, Evalue=7e-29,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_SHEHH (B0TUP7)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674434.1
- ProteinModelPortal:   B0TUP7
- SMR:   B0TUP7
- GeneID:   5905986
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2216
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- ProtClustDB:   CLSK906679
- BioCyc:   SHAL458817:SHAL_2216-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23095; Mature: 23095

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIFAIAALSLPLFSHFPAFAGASDELKVKLTEISSLKANFNQTVTDINDKVIQTGEGV
CCCEEEEEHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHCCCCCHHHHCCCCEEECCCCE
FALSHPNQFYWHLTAPDESLIVADGTDVWIYNPFAEEVSVMDLNQAINASPIALLVHSDD
EEEECCCEEEEEEECCCCCEEEECCCEEEEECCHHHCEEEEEHHHCCCCCCEEEEEECCC
ETWSQYNVSQKENCFDISPKDKDSGGSEVQVCFNDNQLTKMVLKDQQGNISDFTLTNQSV
CCHHHCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEECCEE
IAGKDQDLFKFVVPDDVDIDDQRLKSTN
EECCCCCEEEEECCCCCCCCHHHHCCCC
>Mature Secondary Structure
MKKIFAIAALSLPLFSHFPAFAGASDELKVKLTEISSLKANFNQTVTDINDKVIQTGEGV
CCCEEEEEHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHCCCCCHHHHCCCCEEECCCCE
FALSHPNQFYWHLTAPDESLIVADGTDVWIYNPFAEEVSVMDLNQAINASPIALLVHSDD
EEEECCCEEEEEEECCCCCEEEECCCEEEEECCHHHCEEEEEHHHCCCCCCEEEEEECCC
ETWSQYNVSQKENCFDISPKDKDSGGSEVQVCFNDNQLTKMVLKDQQGNISDFTLTNQSV
CCHHHCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEECCEE
IAGKDQDLFKFVVPDDVDIDDQRLKSTN
EECCCCCEEEEECCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA