Click here to switch to the map view.

The map label for this gene is fadE25 [H]

Identifier: 167624071

GI number: 167624071

Start: 2586332

End: 2587522

Strand: Direct

Name: fadE25 [H]

Synonym: Shal_2147

Alternate gene names: 167624071

Gene position: 2586332-2587522 (Clockwise)

Preceding gene: 167624070

Following gene: 167624075

Centisome position: 49.48

GC content: 42.91

Gene sequence:

>1191_bases
ATGAAACTGAACTTTGATAAAGCGGATGAGTGCTTTCGTCACGAGGTTAGTCAATGGCTTAGTGAAAACTTGAGCGGAGA
ATTTGAATGTGTTCGTGGCCGAGGTGGCCCCGGAGACGAACATATGTTTATTGAAGAGCGTAAGGCGTGGGAGCAAAAAC
TATATCAAGGGGGCTGGACTTGTATTGGTTGGCCAAAAGAGTATGGAGGAAAAGCAGCAAGCATTGTTCAACAAGTTATT
TTTAACGAAGAATATGCAAGGGCCGGTGGACCTGGAAGAATAGGCCATATTGGTGAAACTCTTATTGGGCCGACATTAAT
CGCCTATGGCACTGAAGAGCAAAAACGTCGCTATCTTCCGGGAATTTTAACGGGCACTGAATTTTGGTGTCAGGGTTACT
CAGAGCCCAATGCTGGCTCTGATTTAGCTAACGTACATACCAAAGCTAAGTTTGATGATGAAACTGGACAGTGGTTAATA
AATGGTCAAAAAGTGTGGACATCTCTAGCACATGAATCTCATTATTGTTTTGTAGTTGCTAGAACTGATCCACAGTCTGT
TGGTCAAAAAGGCCTTGGTTTCTTTTTAGTCAAAATGGACCAACCTGAAGTCGATGTTAGACCTATTGCTCAAATGACGT
CGACGAGTGAATTCAATGAAGTGTTTTTTGATGATGCCCCCTGTAGCAACGATGAACTGATTGGTCAGTGTGGCGACGGG
TGGAAAATCGCGATGAGTCTACTCGGATTTGAACGCGGAATTTCAACTCTTGGTCAACAGATGCTTTTCACTAACGAGTT
CAACGATATTGTTAATGCCGCAAAAACAAATGGGGCCGCTGATGATCCGATAATAAGGCAAAGAATTAGCGAGGCTTACA
TCGGATTAAAAATAATGCGTTATAACAGTATGCGTATGTTGTCCAGTTCAAACGCAGACGGAGTCTTATCAAAAGAGGCG
ATGTGCTACAAACTGTATTGGTCAAGCTGGCATCGTAACCTTGGTAAACTTGCTATGGACGTACTAGGCCCCGAAAGTGA
AATTTTAATAGGCAGTCCATACCAACTCAATCAAACGCAATCCATGTACCTCTTTTCTCGCTCTGATACGATCTATGGTG
GAACCAATCAAATTCAACGAAATATTATCGCTGAACGCGCATTAGGAATGCCAAAAGAGCCTAGAGGTTAA

Upstream 100 bases:

>100_bases
TTTATTTTAAACGAGCCAAATCTACCGAGACATATTTAGGAAATAGCGCTTATCACCGTGAGCGTTTAGCCAATCTTATC
CTCAAGCCAGGAGCTTTATT

Downstream 100 bases:

>100_bases
AAGTTAGAAACTTAGAGCCTTGATCCGCCGTTATAGATACGGGCTTGATAAAAGCAATCACTTATTTAAGTAAGGCTTTA
AACAGAAAAGCCCCTATCAA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKLNFDKADECFRHEVSQWLSENLSGEFECVRGRGGPGDEHMFIEERKAWEQKLYQGGWTCIGWPKEYGGKAASIVQQVI
FNEEYARAGGPGRIGHIGETLIGPTLIAYGTEEQKRRYLPGILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLI
NGQKVWTSLAHESHYCFVVARTDPQSVGQKGLGFFLVKMDQPEVDVRPIAQMTSTSEFNEVFFDDAPCSNDELIGQCGDG
WKIAMSLLGFERGISTLGQQMLFTNEFNDIVNAAKTNGAADDPIIRQRISEAYIGLKIMRYNSMRMLSSSNADGVLSKEA
MCYKLYWSSWHRNLGKLAMDVLGPESEILIGSPYQLNQTQSMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG

Sequences:

>Translated_396_residues
MKLNFDKADECFRHEVSQWLSENLSGEFECVRGRGGPGDEHMFIEERKAWEQKLYQGGWTCIGWPKEYGGKAASIVQQVI
FNEEYARAGGPGRIGHIGETLIGPTLIAYGTEEQKRRYLPGILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLI
NGQKVWTSLAHESHYCFVVARTDPQSVGQKGLGFFLVKMDQPEVDVRPIAQMTSTSEFNEVFFDDAPCSNDELIGQCGDG
WKIAMSLLGFERGISTLGQQMLFTNEFNDIVNAAKTNGAADDPIIRQRISEAYIGLKIMRYNSMRMLSSSNADGVLSKEA
MCYKLYWSSWHRNLGKLAMDVLGPESEILIGSPYQLNQTQSMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG
>Mature_396_residues
MKLNFDKADECFRHEVSQWLSENLSGEFECVRGRGGPGDEHMFIEERKAWEQKLYQGGWTCIGWPKEYGGKAASIVQQVI
FNEEYARAGGPGRIGHIGETLIGPTLIAYGTEEQKRRYLPGILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLI
NGQKVWTSLAHESHYCFVVARTDPQSVGQKGLGFFLVKMDQPEVDVRPIAQMTSTSEFNEVFFDDAPCSNDELIGQCGDG
WKIAMSLLGFERGISTLGQQMLFTNEFNDIVNAAKTNGAADDPIIRQRISEAYIGLKIMRYNSMRMLSSSNADGVLSKEA
MCYKLYWSSWHRNLGKLAMDVLGPESEILIGSPYQLNQTQSMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=356, Percent_Identity=27.5280898876405, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4501859, Length=363, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI187960098, Length=344, Percent_Identity=24.4186046511628, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4557231, Length=344, Percent_Identity=24.4186046511628, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4501857, Length=353, Percent_Identity=25.7790368271955, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226958414, Length=212, Percent_Identity=28.3018867924528, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226958412, Length=245, Percent_Identity=26.9387755102041, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21361497, Length=209, Percent_Identity=30.1435406698565, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI87081958, Length=343, Percent_Identity=25.6559766763848, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786223, Length=391, Percent_Identity=24.2966751918159, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508101, Length=341, Percent_Identity=28.1524926686217, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=359, Percent_Identity=25.3481894150418, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=333, Percent_Identity=26.1261261261261, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=216, Percent_Identity=32.4074074074074, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=352, Percent_Identity=23.8636363636364, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=203, Percent_Identity=33.4975369458128, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=218, Percent_Identity=29.8165137614679, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=337, Percent_Identity=24.3323442136499, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=148, Percent_Identity=29.0540540540541, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71985192, Length=148, Percent_Identity=29.0540540540541, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534353, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=363, Percent_Identity=26.4462809917355, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=364, Percent_Identity=27.4725274725275, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=24.0437158469945, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355753, Length=354, Percent_Identity=24.8587570621469, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666513, Length=349, Percent_Identity=24.3553008595989, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363737, Length=149, Percent_Identity=28.8590604026846, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920834, Length=123, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44390; Mature: 44390

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNFDKADECFRHEVSQWLSENLSGEFECVRGRGGPGDEHMFIEERKAWEQKLYQGGWT
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCE
CIGWPKEYGGKAASIVQQVIFNEEYARAGGPGRIGHIGETLIGPTLIAYGTEEQKRRYLP
EECCCHHHCCHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHCCEEEEECCHHHHHHCCC
GILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLINGQKVWTSLAHESHYCFVVA
CEECCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEECHHHHHHHHHCCCEEEEEEE
RTDPQSVGQKGLGFFLVKMDQPEVDVRPIAQMTSTSEFNEVFFDDAPCSNDELIGQCGDG
CCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCHHCCCCCC
WKIAMSLLGFERGISTLGQQMLFTNEFNDIVNAAKTNGAADDPIIRQRISEAYIGLKIMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEE
YNSMRMLSSSNADGVLSKEAMCYKLYWSSWHRNLGKLAMDVLGPESEILIGSPYQLNQTQ
ECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
SMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG
EEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLNFDKADECFRHEVSQWLSENLSGEFECVRGRGGPGDEHMFIEERKAWEQKLYQGGWT
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCE
CIGWPKEYGGKAASIVQQVIFNEEYARAGGPGRIGHIGETLIGPTLIAYGTEEQKRRYLP
EECCCHHHCCHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHCCEEEEECCHHHHHHCCC
GILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLINGQKVWTSLAHESHYCFVVA
CEECCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEECHHHHHHHHHCCCEEEEEEE
RTDPQSVGQKGLGFFLVKMDQPEVDVRPIAQMTSTSEFNEVFFDDAPCSNDELIGQCGDG
CCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCHHCCCCCC
WKIAMSLLGFERGISTLGQQMLFTNEFNDIVNAAKTNGAADDPIIRQRISEAYIGLKIMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEE
YNSMRMLSSSNADGVLSKEAMCYKLYWSSWHRNLGKLAMDVLGPESEILIGSPYQLNQTQ
ECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
SMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG
EEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]