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The map label for this gene is etfA [H]

Identifier: 167624030

GI number: 167624030

Start: 2538269

End: 2539222

Strand: Direct

Name: etfA [H]

Synonym: Shal_2106

Alternate gene names: 167624030

Gene position: 2538269-2539222 (Clockwise)

Preceding gene: 167624029

Following gene: 167624031

Centisome position: 48.56

GC content: 42.56

Gene sequence:

>954_bases
ATGAAAATGTTAGTTATAGCTGAACACGATAATACTCGAATAGCGGACGTGACATTCAATGCCATACAAGCTGCAGCGCA
ACTTGCAACGTATTCAGCAGATGTGAAAATTGAACTATTAATAGCTGGAGCTGATTGCCAAACTGTCGCTGACGAAGCTG
CAACGTTAAGCCACGTAGATACAGTGCGTTGTGTAGAGGCTGCTCATTATGGTGCAGGTTTAGCTGAAAACCTAGCGAGT
CTAGTTGTTGAGCTTACTGCTAAATACCAATACCAGGCAGTGATTGCAGCAAGTAGTAGTTTTGGTAAGAATGTTACTCC
ACGTGTAGCTGCGTTATTGGATGTTGCTCAAGTATCTGATGTTACTGCAATTAATGGTTTCGGTGATTATACAAGGCCAA
TTTATGCCGGTAATATCATGTTAAATTGCGAATCAAGTGATCCAATTCAGGTATTGACGATTAGACCAACGGCTTTTGAT
AAAGTCACAACGGGTGGTAACGCTGAATGTATCCATGAGAACTCGTCACAAGATCTTGGTTTATCGAGATTAATCAGTCG
TGAATTGTCTGAATCAGACAGACCAGAGCTTGGTGCGGCAAATATTATTATTTCTGGAGGCCGTGGCCTAGGTAGTGGTG
ATAACTACAAACAAATCCTTGAACCATTGGCTGATAAACTTGGGGCGGCTTTGGGGGCCTCTCGAGCTGCAGTTGATGCA
GGATATGTACCTAATGATTATCAAGTAGGGCAAACCGGTAAGATTGTTGCACCAGAATTATATATTGCGGTCGGTATTTC
TGGTGCGATTCAGCATCTTGCGGGTATGAGTGATTCACAGGTGATCGTTGCAATTAATAAGGATCCTGATGCTCCCATTT
TTCAGATTGCTGATTATGGCTTGGTTGGAGATCTGTTCACCGCAATTCCAGAGTTAACTAACGCATTAACGTAA

Upstream 100 bases:

>100_bases
CCTCCCGGCGTCACGCAGCGCAGGCGTTATGGTCGATGACGTTGCAGAGTTACTGAGTAAATTGCGTGAAGAAGCGCGAG
TATTATAAGGAGATACTTAA

Downstream 100 bases:

>100_bases
GATTAATGTTATCCGTATAGGTTGGTACAACAGCCTATACGGAACCAATTTAAAATAACTAAAATTAAAAAATTAATTGG
AGGGTATTTTGCCGAATATT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKMLVIAEHDNTRIADVTFNAIQAAAQLATYSADVKIELLIAGADCQTVADEAATLSHVDTVRCVEAAHYGAGLAENLAS
LVVELTAKYQYQAVIAASSSFGKNVTPRVAALLDVAQVSDVTAINGFGDYTRPIYAGNIMLNCESSDPIQVLTIRPTAFD
KVTTGGNAECIHENSSQDLGLSRLISRELSESDRPELGAANIIISGGRGLGSGDNYKQILEPLADKLGAALGASRAAVDA
GYVPNDYQVGQTGKIVAPELYIAVGISGAIQHLAGMSDSQVIVAINKDPDAPIFQIADYGLVGDLFTAIPELTNALT

Sequences:

>Translated_317_residues
MKMLVIAEHDNTRIADVTFNAIQAAAQLATYSADVKIELLIAGADCQTVADEAATLSHVDTVRCVEAAHYGAGLAENLAS
LVVELTAKYQYQAVIAASSSFGKNVTPRVAALLDVAQVSDVTAINGFGDYTRPIYAGNIMLNCESSDPIQVLTIRPTAFD
KVTTGGNAECIHENSSQDLGLSRLISRELSESDRPELGAANIIISGGRGLGSGDNYKQILEPLADKLGAALGASRAAVDA
GYVPNDYQVGQTGKIVAPELYIAVGISGAIQHLAGMSDSQVIVAINKDPDAPIFQIADYGLVGDLFTAIPELTNALT
>Mature_317_residues
MKMLVIAEHDNTRIADVTFNAIQAAAQLATYSADVKIELLIAGADCQTVADEAATLSHVDTVRCVEAAHYGAGLAENLAS
LVVELTAKYQYQAVIAASSSFGKNVTPRVAALLDVAQVSDVTAINGFGDYTRPIYAGNIMLNCESSDPIQVLTIRPTAFD
KVTTGGNAECIHENSSQDLGLSRLISRELSESDRPELGAANIIISGGRGLGSGDNYKQILEPLADKLGAALGASRAAVDA
GYVPNDYQVGQTGKIVAPELYIAVGISGAIQHLAGMSDSQVIVAINKDPDAPIFQIADYGLVGDLFTAIPELTNALT

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=314, Percent_Identity=50, Blast_Score=305, Evalue=2e-83,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=51.2915129151292, Blast_Score=277, Evalue=8e-75,
Organism=Escherichia coli, GI1787990, Length=248, Percent_Identity=30.6451612903226, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786226, Length=231, Percent_Identity=33.7662337662338, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082157, Length=244, Percent_Identity=30.327868852459, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=315, Percent_Identity=52.6984126984127, Blast_Score=325, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6325261, Length=287, Percent_Identity=43.9024390243902, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI17136898, Length=315, Percent_Identity=51.1111111111111, Blast_Score=314, Evalue=4e-86,
Organism=Drosophila melanogaster, GI24652801, Length=315, Percent_Identity=51.1111111111111, Blast_Score=314, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33138; Mature: 33138

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMLVIAEHDNTRIADVTFNAIQAAAQLATYSADVKIELLIAGADCQTVADEAATLSHVD
CEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
TVRCVEAAHYGAGLAENLASLVVELTAKYQYQAVIAASSSFGKNVTPRVAALLDVAQVSD
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCC
VTAINGFGDYTRPIYAGNIMLNCESSDPIQVLTIRPTAFDKVTTGGNAECIHENSSQDLG
CEEECCCCCCCCCEEECEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCH
LSRLISRELSESDRPELGAANIIISGGRGLGSGDNYKQILEPLADKLGAALGASRAAVDA
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCC
GYVPNDYQVGQTGKIVAPELYIAVGISGAIQHLAGMSDSQVIVAINKDPDAPIFQIADYG
CCCCCCCEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCC
LVGDLFTAIPELTNALT
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMLVIAEHDNTRIADVTFNAIQAAAQLATYSADVKIELLIAGADCQTVADEAATLSHVD
CEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
TVRCVEAAHYGAGLAENLASLVVELTAKYQYQAVIAASSSFGKNVTPRVAALLDVAQVSD
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCC
VTAINGFGDYTRPIYAGNIMLNCESSDPIQVLTIRPTAFDKVTTGGNAECIHENSSQDLG
CEEECCCCCCCCCEEECEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCH
LSRLISRELSESDRPELGAANIIISGGRGLGSGDNYKQILEPLADKLGAALGASRAAVDA
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCC
GYVPNDYQVGQTGKIVAPELYIAVGISGAIQHLAGMSDSQVIVAINKDPDAPIFQIADYG
CCCCCCCEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCC
LVGDLFTAIPELTNALT
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]