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The map label for this gene is infC [H]

Identifier: 167623947

GI number: 167623947

Start: 2439427

End: 2439855

Strand: Direct

Name: infC [H]

Synonym: Shal_2021

Alternate gene names: 167623947

Gene position: 2439427-2439855 (Clockwise)

Preceding gene: 167623946

Following gene: 167623948

Centisome position: 46.67

GC content: 44.06

Gene sequence:

>429_bases
TTGACTATTAGAGAAGCACAGGAAGTAGCTGATGAAGCAGGTGTTGATTTAGTAGAAATCAGTCCTAATGCTGAGCCGCC
AGTTTGTCGTGTTATGGACTACGGTAAGTTCCTTTTTGACAAAGCCAAAGCTCAAAAAGAACAAAAGAAGAAGCAGAAAA
TTGTACAGGTGAAGGAAATTAAATTCCGTCCCGGTACAGACGAAAACGATTACCAGGTAAAACTACGCAACCTGACTCGT
TTTCTAGAAGACGGCGACAAAGCGAAAGTAACGCTGCGTTTCCGTGGTCGTGAGATGGCTCACCAAAGCCTAGGTATGGA
TCTTTTGAACCGTATCAAAGCTGATTTGGAAGTCATTGCAGTCGTGGAGTCTTTCCCGAAAATGGAAGGTCGCCAAGCTG
TTATGGTTCTCGCGCCGAAAAAGAAATAG

Upstream 100 bases:

>100_bases
AACAGCAGGGCGCCAGGCGGCCCCGAACAGAATTAACGAGCTCATTACTGGTGTAACAGAAGTCCGTCTTAACGGTCTTG
ACGGTGAGCAACTAGGCATC

Downstream 100 bases:

>100_bases
TAAGGCAACCATAAAAGTAACAGGGGTCTGTTAAGGTCTCTGTTCGCCTTGCGTTTTATTAATTGTCCCAATGCGGAGTT
TTAGCAATGCCTAAAATGAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MTIREAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLTR
FLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK

Sequences:

>Translated_142_residues
MTIREAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLTR
FLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK
>Mature_141_residues
TIREAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLTRF
LEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIAVVESFPKMEGRQAVMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=143, Percent_Identity=77.6223776223776, Blast_Score=213, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 16247; Mature: 16116

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIREAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEI
CCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
KFRPGTDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIA
EECCCCCCCHHEEHHHHHHHHHHCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHH
VVESFPKMEGRQAVMVLAPKKK
HHHHCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
TIREAQEVADEAGVDLVEISPNAEPPVCRVMDYGKFLFDKAKAQKEQKKKQKIVQVKEI
CCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
KFRPGTDENDYQVKLRNLTRFLEDGDKAKVTLRFRGREMAHQSLGMDLLNRIKADLEVIA
EECCCCCCCHHEEHHHHHHHHHHCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHH
VVESFPKMEGRQAVMVLAPKKK
HHHHCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA