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The map label for this gene is nreC [H]

Identifier: 167623909

GI number: 167623909

Start: 2384390

End: 2385058

Strand: Reverse

Name: nreC [H]

Synonym: Shal_1980

Alternate gene names: 167623909

Gene position: 2385058-2384390 (Counterclockwise)

Preceding gene: 167623910

Following gene: 167623908

Centisome position: 45.63

GC content: 42.6

Gene sequence:

>669_bases
ATGTCTGAAAAAATTACAATTATACTCGTCGACGATCATATATTAGTCCGAGCAGGGATCCGGTCCTTATTGGAGTCCAT
AGCCAATGTTGAGGTCATTAAAGAATCGGGAGATGGTATTGAAGCTCTGTCATTACTGCGAACTCACCAACCGACGCTGT
TAATTTTAGATATCTCTTTGCCCGGATTAAATGGACTCGAGGTTGCACGTAGCGTCACCAAGATGAAGACCAAGACAAAA
ATTTTAATGCTCTCTATGCATAGTGACGTTGAATACGTTGCAAAAGCGCTCACCATAGGAAGCCATGGTTACCTAATGAA
AGAATCCGCTGTGGAAGAATTAGAAACCGCTATTTCGACACTGATTAACGACAAACAATATATCGGTAAAAATATTGATC
TGGAAATGGTCGACAAACTTAGAGGCGATAGCAATCAAGAGAGTGACTTAATAAAACTGCTGACTAGCCGTCAGCGACAG
ATCCTACAACTGATTGCCGAAGGTTACTCAACAAGAGAAATAGCCGAACGCATGAGTGTCAGCATTAAGACGGTTGAAAC
CCATCGCGCCCATATTATGTCCCGCCTTAATATATTTGATATTGCCGGGCTCGTACGGTTCGCCATTCGCTGCAAACTTA
TTTGCTTGAATGAGGCTCCCATCAGTTGA

Upstream 100 bases:

>100_bases
GGGCTACTCGGTATGGAAGAGCGCGTTCATTCGTTATCCGGTAAGTTATTACTTCACTCAAGCATCAGTAATGGTTCAAT
AATCAAGGTGGTGATCCCTA

Downstream 100 bases:

>100_bases
ATCACTCCACCGAATCAACCACTTAGCTTAAAACAGATACAACTAGCAGCCAACCTCTACTTAGTTAACGCTTGCTGCAG
TTAATCACTCCATATGACAC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSEKITIILVDDHILVRAGIRSLLESIANVEVIKESGDGIEALSLLRTHQPTLLILDISLPGLNGLEVARSVTKMKTKTK
ILMLSMHSDVEYVAKALTIGSHGYLMKESAVEELETAISTLINDKQYIGKNIDLEMVDKLRGDSNQESDLIKLLTSRQRQ
ILQLIAEGYSTREIAERMSVSIKTVETHRAHIMSRLNIFDIAGLVRFAIRCKLICLNEAPIS

Sequences:

>Translated_222_residues
MSEKITIILVDDHILVRAGIRSLLESIANVEVIKESGDGIEALSLLRTHQPTLLILDISLPGLNGLEVARSVTKMKTKTK
ILMLSMHSDVEYVAKALTIGSHGYLMKESAVEELETAISTLINDKQYIGKNIDLEMVDKLRGDSNQESDLIKLLTSRQRQ
ILQLIAEGYSTREIAERMSVSIKTVETHRAHIMSRLNIFDIAGLVRFAIRCKLICLNEAPIS
>Mature_221_residues
SEKITIILVDDHILVRAGIRSLLESIANVEVIKESGDGIEALSLLRTHQPTLLILDISLPGLNGLEVARSVTKMKTKTKI
LMLSMHSDVEYVAKALTIGSHGYLMKESAVEELETAISTLINDKQYIGKNIDLEMVDKLRGDSNQESDLIKLLTSRQRQI
LQLIAEGYSTREIAERMSVSIKTVETHRAHIMSRLNIFDIAGLVRFAIRCKLICLNEAPIS

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=35.9223300970874, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=33.1683168316832, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=25, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=28.5024154589372, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=30.1075268817204, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=25.2427184466019, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24735; Mature: 24604

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKITIILVDDHILVRAGIRSLLESIANVEVIKESGDGIEALSLLRTHQPTLLILDISL
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCEEEEEEECC
PGLNGLEVARSVTKMKTKTKILMLSMHSDVEYVAKALTIGSHGYLMKESAVEELETAIST
CCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LINDKQYIGKNIDLEMVDKLRGDSNQESDLIKLLTSRQRQILQLIAEGYSTREIAERMSV
HHCCHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SIKTVETHRAHIMSRLNIFDIAGLVRFAIRCKLICLNEAPIS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCC
>Mature Secondary Structure 
SEKITIILVDDHILVRAGIRSLLESIANVEVIKESGDGIEALSLLRTHQPTLLILDISL
CCEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCEEEEEEECC
PGLNGLEVARSVTKMKTKTKILMLSMHSDVEYVAKALTIGSHGYLMKESAVEELETAIST
CCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LINDKQYIGKNIDLEMVDKLRGDSNQESDLIKLLTSRQRQILQLIAEGYSTREIAERMSV
HHCCHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SIKTVETHRAHIMSRLNIFDIAGLVRFAIRCKLICLNEAPIS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]