Click here to switch to the map view.

The map label for this gene is zitB [H]

Identifier: 167623884

GI number: 167623884

Start: 2348562

End: 2349581

Strand: Direct

Name: zitB [H]

Synonym: Shal_1954

Alternate gene names: 167623884

Gene position: 2348562-2349581 (Clockwise)

Preceding gene: 167623882

Following gene: 167623885

Centisome position: 44.93

GC content: 42.84

Gene sequence:

>1020_bases
ATGATCTATGGTGAACAAGCTGCCGTGAACTGCGCAGATAAACACAAGTTTTCGACTCAAAATAGTGCAGGAGAGCGCAA
TACCGCCTATGTATTAGTGCTTACGATAGTGACCATGCTGGCAGAGATCATTGCCGGTACTATTTATGGCTCTATGGCGT
TATTAGCCGATGGCTGGCATATGGGAACTCATGCTGCGGCATTTTTGATAACTCTTTTTGCATATCGATATGCGCGTAAG
CATGCAAACTCCCCAGAGTTTTCTTACGGGACTGGAAAAGTGAGTGTGCTTGGAGGATATACTAGTGCAATCGCACTGGG
TTTAGTTGCCCTCGTTATGTTAATTGAGTCGAGTGTGAGGATCTTTAATCCCCATGAGATCTATTTCAATCAGGCAATTG
TGGTGGCGATTATCGGGCTTATTGTTAACGTGGTCAGTGTATTTTTATTGAAAGATCATCATAGTCACGATCATGGACAT
AGCCACAGTCATCATGACCATGATGTACACAAAGGAGTGATCCAAGATGAAAAATACCACGATCACAATCATGGATATCA
TGAGCATAGTGATGGAGAGAAGCATCACGGCCAAGATCACAACCTGAGGGCTGCTTATTTTCACGTACTTGCCGATGCGC
TCACTTCGCTCTTGGCAATAGCTGCTTTACTGATGGGCAAATACTTTGGCCTAACTTGGCTAGACCCTATTATGGGCATT
GTTGGTGCAGTGATTATTACTCGCTGGGCATGGGGACTACTAAAACAAACGGGCCCAGTATTGTTGGATGCAAGTATTGA
GCAAAGCTACATGCAACAGATTAAACAAACCATTGAACAAGAAAGCGCACAGCTTGTTGACCTCCATATTTGGAAAATCA
GTGCCGACCATTATGCTGCTAGTATGATCATTCATTGTGATCGGGTTGAAAAATCAGGTTATTTTAAGGAAAAATTATCA
CAATTTGAGCGCTTAGCTCATATCACTATTGAAGTTAATCCAGAGACTCAGGCACAATAA

Upstream 100 bases:

>100_bases
GGCAAGGCTGAGCTATAAACAGAAATGATTGATAATAATTAAACGATAGCCGTGGGCTTGATGGTAAGACGTCTAAATCC
AAAATATTCAAGGGTGTTAT

Downstream 100 bases:

>100_bases
GGCTACACTAACGAGGAATAAAATTAATGAAAAACCAAGATGATAGCTTAAATCATGCAATGATCGAGTTTTACGAGAAG
TTGTCATCTTGGGAAATGGC

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIYGEQAAVNCADKHKFSTQNSAGERNTAYVLVLTIVTMLAEIIAGTIYGSMALLADGWHMGTHAAAFLITLFAYRYARK
HANSPEFSYGTGKVSVLGGYTSAIALGLVALVMLIESSVRIFNPHEIYFNQAIVVAIIGLIVNVVSVFLLKDHHSHDHGH
SHSHHDHDVHKGVIQDEKYHDHNHGYHEHSDGEKHHGQDHNLRAAYFHVLADALTSLLAIAALLMGKYFGLTWLDPIMGI
VGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIKQTIEQESAQLVDLHIWKISADHYAASMIIHCDRVEKSGYFKEKLS
QFERLAHITIEVNPETQAQ

Sequences:

>Translated_339_residues
MIYGEQAAVNCADKHKFSTQNSAGERNTAYVLVLTIVTMLAEIIAGTIYGSMALLADGWHMGTHAAAFLITLFAYRYARK
HANSPEFSYGTGKVSVLGGYTSAIALGLVALVMLIESSVRIFNPHEIYFNQAIVVAIIGLIVNVVSVFLLKDHHSHDHGH
SHSHHDHDVHKGVIQDEKYHDHNHGYHEHSDGEKHHGQDHNLRAAYFHVLADALTSLLAIAALLMGKYFGLTWLDPIMGI
VGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIKQTIEQESAQLVDLHIWKISADHYAASMIIHCDRVEKSGYFKEKLS
QFERLAHITIEVNPETQAQ
>Mature_339_residues
MIYGEQAAVNCADKHKFSTQNSAGERNTAYVLVLTIVTMLAEIIAGTIYGSMALLADGWHMGTHAAAFLITLFAYRYARK
HANSPEFSYGTGKVSVLGGYTSAIALGLVALVMLIESSVRIFNPHEIYFNQAIVVAIIGLIVNVVSVFLLKDHHSHDHGH
SHSHHDHDVHKGVIQDEKYHDHNHGYHEHSDGEKHHGQDHNLRAAYFHVLADALTSLLAIAALLMGKYFGLTWLDPIMGI
VGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIKQTIEQESAQLVDLHIWKISADHYAASMIIHCDRVEKSGYFKEKLS
QFERLAHITIEVNPETQAQ

Specific function: Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI222080086, Length=311, Percent_Identity=28.6173633440514, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI40255009, Length=311, Percent_Identity=28.6173633440514, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI20070323, Length=283, Percent_Identity=29.3286219081272, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI21359890, Length=308, Percent_Identity=23.7012987012987, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI52351208, Length=124, Percent_Identity=28.2258064516129, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786966, Length=271, Percent_Identity=27.3062730627306, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564488, Length=319, Percent_Identity=25.705329153605, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210990, Length=336, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555796, Length=291, Percent_Identity=26.8041237113402, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555794, Length=275, Percent_Identity=26.9090909090909, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323899, Length=331, Percent_Identity=28.3987915407855, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324892, Length=339, Percent_Identity=22.7138643067847, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24656728, Length=311, Percent_Identity=26.3665594855305, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656724, Length=311, Percent_Identity=26.3665594855305, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656720, Length=311, Percent_Identity=26.3665594855305, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656715, Length=311, Percent_Identity=26.3665594855305, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357035, Length=311, Percent_Identity=26.3665594855305, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24645863, Length=331, Percent_Identity=24.1691842900302, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 37744; Mature: 37744

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGEQAAVNCADKHKFSTQNSAGERNTAYVLVLTIVTMLAEIIAGTIYGSMALLADGWH
CCCCCCHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MGTHAAAFLITLFAYRYARKHANSPEFSYGTGKVSVLGGYTSAIALGLVALVMLIESSVR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCE
IFNPHEIYFNQAIVVAIIGLIVNVVSVFLLKDHHSHDHGHSHSHHDHDVHKGVIQDEKYH
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCC
DHNHGYHEHSDGEKHHGQDHNLRAAYFHVLADALTSLLAIAALLMGKYFGLTWLDPIMGI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIKQTIEQESAQLVDLHIWKISADHYAA
HHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHH
SMIIHCDRVEKSGYFKEKLSQFERLAHITIEVNPETQAQ
HHHHEEHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCC
>Mature Secondary Structure
MIYGEQAAVNCADKHKFSTQNSAGERNTAYVLVLTIVTMLAEIIAGTIYGSMALLADGWH
CCCCCCHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MGTHAAAFLITLFAYRYARKHANSPEFSYGTGKVSVLGGYTSAIALGLVALVMLIESSVR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCE
IFNPHEIYFNQAIVVAIIGLIVNVVSVFLLKDHHSHDHGHSHSHHDHDVHKGVIQDEKYH
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCC
DHNHGYHEHSDGEKHHGQDHNLRAAYFHVLADALTSLLAIAALLMGKYFGLTWLDPIMGI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIKQTIEQESAQLVDLHIWKISADHYAA
HHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHH
SMIIHCDRVEKSGYFKEKLSQFERLAHITIEVNPETQAQ
HHHHEEHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]