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The map label for this gene is pilH [H]

Identifier: 167623837

GI number: 167623837

Start: 2290367

End: 2290729

Strand: Reverse

Name: pilH [H]

Synonym: Shal_1907

Alternate gene names: 167623837

Gene position: 2290729-2290367 (Counterclockwise)

Preceding gene: 167623840

Following gene: 167623828

Centisome position: 43.83

GC content: 42.42

Gene sequence:

>363_bases
ATGAAAAAAGCGAGAATACTGGTCGTAGATGATGATCCAGTCTGTTCAAGCCTATTATTGTCTATATTAGGCGATGACTA
TCAGGTCACAACCGTAAACACAGGTTGTGATGTTGCGGATATTGCAAATATTCAGCGTCCGGACGTTATCTTCTTAGATA
TCATGATGCCCGGCAAAAATGGTTACCAAGTCCTTAAAGATCTGAAACAAGACCCACAAACATCTAAACTGCCGGTCATT
ATCGTCAGCGCCCTTTCAGAACAGTCTGATGAAAACCTTGCACTGCGGATCGGTGCAGACGGCTACATAACAAAACCTAT
TGTGCCATCGAGTGTGTTTGCTGTACTTAAGAAGTATCTCTAA

Upstream 100 bases:

>100_bases
AATAACTGTGTTAAAAATAGCCAATATTCCTGTAAAATGATAGAGTTGTTAGATAAACGTTGTAACTCGATTCCAGCTTG
AGCTTAAGAGGATAATCTAA

Downstream 100 bases:

>100_bases
TGAAGCTGAAGTGCTAATCAATAAAAACCATTTATTGCTAACTATTGCTAATTGCAAAACATTAGTGATGGATACCGCTG
GCGAAAAATGCCCGTTTACA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MKKARILVVDDDPVCSSLLLSILGDDYQVTTVNTGCDVADIANIQRPDVIFLDIMMPGKNGYQVLKDLKQDPQTSKLPVI
IVSALSEQSDENLALRIGADGYITKPIVPSSVFAVLKKYL

Sequences:

>Translated_120_residues
MKKARILVVDDDPVCSSLLLSILGDDYQVTTVNTGCDVADIANIQRPDVIFLDIMMPGKNGYQVLKDLKQDPQTSKLPVI
IVSALSEQSDENLALRIGADGYITKPIVPSSVFAVLKKYL
>Mature_120_residues
MKKARILVVDDDPVCSSLLLSILGDDYQVTTVNTGCDVADIANIQRPDVIFLDIMMPGKNGYQVLKDLKQDPQTSKLPVI
IVSALSEQSDENLALRIGADGYITKPIVPSSVFAVLKKYL

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=35.0877192982456, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=36.7521367521368, Blast_Score=72, Evalue=7e-15,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1790860, Length=121, Percent_Identity=31.404958677686, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786911, Length=113, Percent_Identity=35.3982300884956, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=103, Percent_Identity=33.0097087378641, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=115, Percent_Identity=33.0434782608696, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=30.0884955752212, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13093; Mature: 13093

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKARILVVDDDPVCSSLLLSILGDDYQVTTVNTGCDVADIANIQRPDVIFLDIMMPGKN
CCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCEEEEEEEECCCC
GYQVLKDLKQDPQTSKLPVIIVSALSEQSDENLALRIGADGYITKPIVPSSVFAVLKKYL
CHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKARILVVDDDPVCSSLLLSILGDDYQVTTVNTGCDVADIANIQRPDVIFLDIMMPGKN
CCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCEEEEEEEECCCC
GYQVLKDLKQDPQTSKLPVIIVSALSEQSDENLALRIGADGYITKPIVPSSVFAVLKKYL
CHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]