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The map label for this gene is sbcB [H]

Identifier: 167623714

GI number: 167623714

Start: 2134513

End: 2135994

Strand: Reverse

Name: sbcB [H]

Synonym: Shal_1784

Alternate gene names: 167623714

Gene position: 2135994-2134513 (Counterclockwise)

Preceding gene: 167623717

Following gene: 167623713

Centisome position: 40.87

GC content: 43.66

Gene sequence:

>1482_bases
ATGCAAACGAACAAAACTCAACCTAAGCCATTAATAGTAAAGACCAAAACCACTTTAAAACGGAACAAAGAAAACATGAG
TGAACACCCAACTATCTTCTGGCACGATTACGAAACTTTTGGTGCCAATCCAGCGAAAGATAGACCTTCTCAGTTTGCTG
GCGTGCGCACGGATCTAGATCTTAATATCATCGGCGAGCCCGAAACCTTTTACTGTAAACTTGCTAATGACTATCTACCG
TCACCAGAGGCTATCCTTATCACAGGTATTACTCCGCAACTCGCAAACCTTAAAGGTATGCCAGAAGCCGAGTTTATGGA
CAAAATTAATGGCCTGTTTAGTCAACCTAAGACCTGTGTTGTGGGTTATAACTCATTGCGCTTTGATGATGAAGTGTCGC
GCTACGGCTTTTATCGTAATTTTATCGACCCTTATGCCCGTGAGTGGCAAAACGGTAACACCCGCTGGGATATTATTGAT
CTTGTTCGCGCGTGCTATGCTTTTAGACCCGAAGGCATTAACTGGCCTGAAAAAGAAGATGGCTCTCCTAGCTTTAAGCT
TGAACAACTGACCGTAGCCAATGGCTTAAGCCATGAAAAGGCTCATGATGCGATGTCTGATGTATATGCCACTATCGACA
TGGCAAAGCTGATTAAAACGGTACAACCTAAGCTGTTTGATTATTACTTTAGCCTGAGGCAGAAGCAGCAAGTATCGAAG
CTCATCGATGTGCTTGAAATGAAACCACTTGTACATGTTAGTTCTAAAATCAGCGCCTTAAACGGTTGCACCACTATCAT
TGCGCCAGTGGCTTACCACTCTACCAACAAAAATGCCGTTATTTGTGTCAACTTGGCTATGGACGTCACTCCGCTTATCG
AACTGAGTGTTGAAGAAATTCGTGAGCGCATGTATACCCGCCGCAGTGATTTAGCCCCCGATGAACTGCCTATCGGCTTA
AAACAGGTCCATATCAATAAGAGTCCTTTTATTGCTGCTGCTAATACGTTAACTGACGAGAACGCCGCCAGACTCGATTT
TGATAAAGCATTTGCCAGAGAGCAGTTCAGGAAGTTAAAGCAACACCCAGAGTTAAGAGAAAAGCTGGTTGCGGTATTTG
ATGTTGAGCATGACAGCAAAGCTGTGGATCCTGACCAAGCCCTTTACAGTGGTGGCTTCTTCAGTAGTGCCGATAAAGCT
AAAATCGAGATAATCCGCAATACTAAGCCAAGTAATCTGGCGGCACTAGAACTGGACTTCGATGACTCAAGACTAGCAGA
GATGCTGTTTAGGTACCGAGCACGTAACTATCCAGAAACTCTCGATGATAGTGAGCAGTATCGCTGGCGAGAATTTTGCC
AAACCAGACTCAATGACCCAGATTACATCATTCGTCTGGAGAATTTGCTTGAAGAAACCGAGCAAGATGAATCTAAACAA
AAACTATTACAGGCTTTATGTCATTATCTTAGAAACCTATAG

Upstream 100 bases:

>100_bases
CCGTTGCAGTCTCTGTGTACACATGAACAATTTACTTTATGCACACTCAAATGTACACAATGTTTCTAGAACAGCATTAA
ACAACAATGTTCAGATATGA

Downstream 100 bases:

>100_bases
GCTTTATAGGCGACAACTGAGATCTTCATCTCATTCTAGATGTAACAAGCTTACTAGAATGATACTTCATTGGTGTTAAT
AAAAGGAAATAGCATATGCA

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MQTNKTQPKPLIVKTKTTLKRNKENMSEHPTIFWHDYETFGANPAKDRPSQFAGVRTDLDLNIIGEPETFYCKLANDYLP
SPEAILITGITPQLANLKGMPEAEFMDKINGLFSQPKTCVVGYNSLRFDDEVSRYGFYRNFIDPYAREWQNGNTRWDIID
LVRACYAFRPEGINWPEKEDGSPSFKLEQLTVANGLSHEKAHDAMSDVYATIDMAKLIKTVQPKLFDYYFSLRQKQQVSK
LIDVLEMKPLVHVSSKISALNGCTTIIAPVAYHSTNKNAVICVNLAMDVTPLIELSVEEIRERMYTRRSDLAPDELPIGL
KQVHINKSPFIAAANTLTDENAARLDFDKAFAREQFRKLKQHPELREKLVAVFDVEHDSKAVDPDQALYSGGFFSSADKA
KIEIIRNTKPSNLAALELDFDDSRLAEMLFRYRARNYPETLDDSEQYRWREFCQTRLNDPDYIIRLENLLEETEQDESKQ
KLLQALCHYLRNL

Sequences:

>Translated_493_residues
MQTNKTQPKPLIVKTKTTLKRNKENMSEHPTIFWHDYETFGANPAKDRPSQFAGVRTDLDLNIIGEPETFYCKLANDYLP
SPEAILITGITPQLANLKGMPEAEFMDKINGLFSQPKTCVVGYNSLRFDDEVSRYGFYRNFIDPYAREWQNGNTRWDIID
LVRACYAFRPEGINWPEKEDGSPSFKLEQLTVANGLSHEKAHDAMSDVYATIDMAKLIKTVQPKLFDYYFSLRQKQQVSK
LIDVLEMKPLVHVSSKISALNGCTTIIAPVAYHSTNKNAVICVNLAMDVTPLIELSVEEIRERMYTRRSDLAPDELPIGL
KQVHINKSPFIAAANTLTDENAARLDFDKAFAREQFRKLKQHPELREKLVAVFDVEHDSKAVDPDQALYSGGFFSSADKA
KIEIIRNTKPSNLAALELDFDDSRLAEMLFRYRARNYPETLDDSEQYRWREFCQTRLNDPDYIIRLENLLEETEQDESKQ
KLLQALCHYLRNL
>Mature_493_residues
MQTNKTQPKPLIVKTKTTLKRNKENMSEHPTIFWHDYETFGANPAKDRPSQFAGVRTDLDLNIIGEPETFYCKLANDYLP
SPEAILITGITPQLANLKGMPEAEFMDKINGLFSQPKTCVVGYNSLRFDDEVSRYGFYRNFIDPYAREWQNGNTRWDIID
LVRACYAFRPEGINWPEKEDGSPSFKLEQLTVANGLSHEKAHDAMSDVYATIDMAKLIKTVQPKLFDYYFSLRQKQQVSK
LIDVLEMKPLVHVSSKISALNGCTTIIAPVAYHSTNKNAVICVNLAMDVTPLIELSVEEIRERMYTRRSDLAPDELPIGL
KQVHINKSPFIAAANTLTDENAARLDFDKAFAREQFRKLKQHPELREKLVAVFDVEHDSKAVDPDQALYSGGFFSSADKA
KIEIIRNTKPSNLAALELDFDDSRLAEMLFRYRARNYPETLDDSEQYRWREFCQTRLNDPDYIIRLENLLEETEQDESKQ
KLLQALCHYLRNL

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=467, Percent_Identity=53.1049250535332, Blast_Score=507, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 56715; Mature: 56715

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTNKTQPKPLIVKTKTTLKRNKENMSEHPTIFWHDYETFGANPAKDRPSQFAGVRTDLD
CCCCCCCCCCEEEECHHHHHHCHHCHHHCCEEEEECHHHCCCCCCCCCCHHHCCCEECCE
LNIIGEPETFYCKLANDYLPSPEAILITGITPQLANLKGMPEAEFMDKINGLFSQPKTCV
EEEECCCCEEEEEECCCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
VGYNSLRFDDEVSRYGFYRNFIDPYAREWQNGNTRWDIIDLVRACYAFRPEGINWPEKED
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCC
GSPSFKLEQLTVANGLSHEKAHDAMSDVYATIDMAKLIKTVQPKLFDYYFSLRQKQQVSK
CCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDVLEMKPLVHVSSKISALNGCTTIIAPVAYHSTNKNAVICVNLAMDVTPLIELSVEEI
HHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHEECCCCCEEEEEEECCCCCHHHHHHHHHH
RERMYTRRSDLAPDELPIGLKQVHINKSPFIAAANTLTDENAARLDFDKAFAREQFRKLK
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCHHCCHHHHHHHHHHHHHH
QHPELREKLVAVFDVEHDSKAVDPDQALYSGGFFSSADKAKIEIIRNTKPSNLAALELDF
HCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEECC
DDSRLAEMLFRYRARNYPETLDDSEQYRWREFCQTRLNDPDYIIRLENLLEETEQDESKQ
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHCCHHHH
KLLQALCHYLRNL
HHHHHHHHHHHCC
>Mature Secondary Structure
MQTNKTQPKPLIVKTKTTLKRNKENMSEHPTIFWHDYETFGANPAKDRPSQFAGVRTDLD
CCCCCCCCCCEEEECHHHHHHCHHCHHHCCEEEEECHHHCCCCCCCCCCHHHCCCEECCE
LNIIGEPETFYCKLANDYLPSPEAILITGITPQLANLKGMPEAEFMDKINGLFSQPKTCV
EEEECCCCEEEEEECCCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
VGYNSLRFDDEVSRYGFYRNFIDPYAREWQNGNTRWDIIDLVRACYAFRPEGINWPEKED
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCC
GSPSFKLEQLTVANGLSHEKAHDAMSDVYATIDMAKLIKTVQPKLFDYYFSLRQKQQVSK
CCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDVLEMKPLVHVSSKISALNGCTTIIAPVAYHSTNKNAVICVNLAMDVTPLIELSVEEI
HHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHEECCCCCEEEEEEECCCCCHHHHHHHHHH
RERMYTRRSDLAPDELPIGLKQVHINKSPFIAAANTLTDENAARLDFDKAFAREQFRKLK
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCHHCCHHHHHHHHHHHHHH
QHPELREKLVAVFDVEHDSKAVDPDQALYSGGFFSSADKAKIEIIRNTKPSNLAALELDF
HCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEECC
DDSRLAEMLFRYRARNYPETLDDSEQYRWREFCQTRLNDPDYIIRLENLLEETEQDESKQ
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHCCHHHH
KLLQALCHYLRNL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]