Click here to switch to the map view.

The map label for this gene is trpG [H]

Identifier: 167623588

GI number: 167623588

Start: 1987706

End: 1988320

Strand: Reverse

Name: trpG [H]

Synonym: Shal_1657

Alternate gene names: 167623588

Gene position: 1988320-1987706 (Counterclockwise)

Preceding gene: 167623589

Following gene: 167623587

Centisome position: 38.04

GC content: 46.18

Gene sequence:

>615_bases
ATGAAAATCTATCTGTTAGATAACTTTGACTCCTTCACTTACAACCTAGTCGATCAGTTTAGAAGTCTAGGCTACGAAGT
GGTGATTTATCGTAATGATGTCGATGCTAACTTTATCGCTGACAAATTGTTAAATGAAACCGTACCCGCTGCGCTTGTGC
TGTCCCCAGGTCCTGGCGCGCCCCATGAAGCGGGCTCATTAATGGCCTTGATTGAGTGCGTTGCAGGCAAAGTGCCTATG
CTGGGTATTTGCCTTGGTCATCAAGCCTTAGTGGAACATTACGGCGGCAAAGTGGAACGCGCCAGACAAGTGGTTCATGG
TAAGGCAAGCCCGACTTACCATAACGGTACCGATATCTTTGCAGATCTCCCCTCACCACTTCCGGTTGCTCGTTATCACA
GCTTAGTCGCAACCCAAGTACCCGATTGCCTAGAGGTCATTGCGACGACTGAGGATATGCCAATGGCAATTATCCACAGA
CAAGATAAAGCGGTGGGCTTTCAGTTTCATCCAGAATCAATTTTAACCACCTTAGGTAGCCAGCTATTAGTACAAAGCTT
AGATTATCTTTCTCGCGCATTAGCTAATAACAGCCACGATAACGAAAAAGGATAA

Upstream 100 bases:

>100_bases
GAGCCGGCGTGGTATTTGATTCAGACCCTCAGGCGGAAGCCGATGAAACCCGCCAAAAGGCACAAGCGGTTATTTCAGCC
ATTAAGATGGGAGGTGGGCT

Downstream 100 bases:

>100_bases
GATGATGAGTCAAACAAAAATCACTCACTCCACAATTAAATCTACTGAAGCGCTTATCGAATCCCTTTACCGCGGCGAGA
GCTTATCTCGACAAGACGCT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKIYLLDNFDSFTYNLVDQFRSLGYEVVIYRNDVDANFIADKLLNETVPAALVLSPGPGAPHEAGSLMALIECVAGKVPM
LGICLGHQALVEHYGGKVERARQVVHGKASPTYHNGTDIFADLPSPLPVARYHSLVATQVPDCLEVIATTEDMPMAIIHR
QDKAVGFQFHPESILTTLGSQLLVQSLDYLSRALANNSHDNEKG

Sequences:

>Translated_204_residues
MKIYLLDNFDSFTYNLVDQFRSLGYEVVIYRNDVDANFIADKLLNETVPAALVLSPGPGAPHEAGSLMALIECVAGKVPM
LGICLGHQALVEHYGGKVERARQVVHGKASPTYHNGTDIFADLPSPLPVARYHSLVATQVPDCLEVIATTEDMPMAIIHR
QDKAVGFQFHPESILTTLGSQLLVQSLDYLSRALANNSHDNEKG
>Mature_204_residues
MKIYLLDNFDSFTYNLVDQFRSLGYEVVIYRNDVDANFIADKLLNETVPAALVLSPGPGAPHEAGSLMALIECVAGKVPM
LGICLGHQALVEHYGGKVERARQVVHGKASPTYHNGTDIFADLPSPLPVARYHSLVATQVPDCLEVIATTEDMPMAIIHR
QDKAVGFQFHPESILTTLGSQLLVQSLDYLSRALANNSHDNEKG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=53.6458333333333, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=48.936170212766, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788854, Length=191, Percent_Identity=29.3193717277487, Blast_Score=68, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=39.6825396825397, Blast_Score=142, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324361, Length=220, Percent_Identity=28.6363636363636, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22285; Mature: 22285

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYLLDNFDSFTYNLVDQFRSLGYEVVIYRNDVDANFIADKLLNETVPAALVLSPGPGA
CEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCC
PHEAGSLMALIECVAGKVPMLGICLGHQALVEHYGGKVERARQVVHGKASPTYHNGTDIF
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEE
ADLPSPLPVARYHSLVATQVPDCLEVIATTEDMPMAIIHRQDKAVGFQFHPESILTTLGS
ECCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCCEEECHHHHHHHHHH
QLLVQSLDYLSRALANNSHDNEKG
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKIYLLDNFDSFTYNLVDQFRSLGYEVVIYRNDVDANFIADKLLNETVPAALVLSPGPGA
CEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCC
PHEAGSLMALIECVAGKVPMLGICLGHQALVEHYGGKVERARQVVHGKASPTYHNGTDIF
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEE
ADLPSPLPVARYHSLVATQVPDCLEVIATTEDMPMAIIHRQDKAVGFQFHPESILTTLGS
ECCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCCEEECHHHHHHHHHH
QLLVQSLDYLSRALANNSHDNEKG
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1773058; 12620739 [H]