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The map label for this gene is int [H]

Identifier: 167623565

GI number: 167623565

Start: 1962081

End: 1963043

Strand: Reverse

Name: int [H]

Synonym: Shal_1634

Alternate gene names: 167623565

Gene position: 1963043-1962081 (Counterclockwise)

Preceding gene: 167623569

Following gene: 167623564

Centisome position: 37.56

GC content: 43.51

Gene sequence:

>963_bases
ATGGCAGCTATAAAAAGTCCTTTTCTGACTCAAGTTCGTGAACATATGCGTATGCGCGGTTACAGTATCAAAACAGAAAA
AGCATACTTGTACTGGATTAAAGCCTTTATCAACTTCCAGCAAAAGCGTCACCCAGAAACAATGGGACAAGCTGAAGTGA
CACAATTCCTCAGTTTTCTGGCTAACTCACGTAATGTTGCGATTAATACACAGAAAGTGGCGCTCAATGCTCTTGTGTAC
CTTTATCATAAGCATCTAAAGCAAGATCTAGGTGACCTGGGGTTTAGATATGCCACCAAACAAAGGCAGTTACCTATTGT
GCTATCAACCGAAGAAGTTTCTGAGGTTCTTTGTCAGCTTAATGGGCGAGACCAACTTATTGTCCAGTTACTATATGGCA
GCGGACTGCGGGTTTCAGAATGTTTAAGGTTACGTATTCAAGATATCGATCTAGCACGCTGCTCACTCACTGTCAGAAAT
GGCAAAGGCCATAAAGACAGACAAACCATTCTCAGTCAAAAATGTGCAATCAAACTACCTGCTTATATCGATGCTGCGCG
TGCTATTCAGATTAAGGACAATACCTATTGTATAGGGCCATCTTTACCCAATGCGCTAGAGCGTAAGTACCCCAATGCAT
TTAGGCAAGCTGGCTGGATGTTTGTTTTTCCATCAACCACCACAAGTGATAATCCATACACTAAGACTCACTGTAGACAC
CATTTACATCAGAGTGTCATTCGAAAAGCACTTGCAGCTGCGGTGCGAAAAACCCATATCATCAAACGTGTCACTTGCCA
TACCTTCAGGCACAGCTTTGCCACCCATTTACTTCAAGCTGGGCGGGACATAAGAACTATTCAGGAGCTACTGGGCCACA
ATGATGTCAATACCACTCAAATCTACACTCACGTGCTTGGCCAACATTACGCAGGAACGGTGAGTCCGCTAGATAGTCTG
TAA

Upstream 100 bases:

>100_bases
AGCCTCAAGTGCAAGCGCACATAATTTACACAATTTTTCCCTGAAGAATCGAGTAAAGTAGATAATACTGTATAGATAAA
CAGTGAGCAGGTTATTTATC

Downstream 100 bases:

>100_bases
CATGACAATCACTGAACCAAATAGGATTCAAAAATATATTAAGGAGAGGGAAACTCTGTAATCATCAAACTGCAGGTGCT
AATTCGTTTTGGAACAAAAG

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAAIKSPFLTQVREHMRMRGYSIKTEKAYLYWIKAFINFQQKRHPETMGQAEVTQFLSFLANSRNVAINTQKVALNALVY
LYHKHLKQDLGDLGFRYATKQRQLPIVLSTEEVSEVLCQLNGRDQLIVQLLYGSGLRVSECLRLRIQDIDLARCSLTVRN
GKGHKDRQTILSQKCAIKLPAYIDAARAIQIKDNTYCIGPSLPNALERKYPNAFRQAGWMFVFPSTTTSDNPYTKTHCRH
HLHQSVIRKALAAAVRKTHIIKRVTCHTFRHSFATHLLQAGRDIRTIQELLGHNDVNTTQIYTHVLGQHYAGTVSPLDSL

Sequences:

>Translated_320_residues
MAAIKSPFLTQVREHMRMRGYSIKTEKAYLYWIKAFINFQQKRHPETMGQAEVTQFLSFLANSRNVAINTQKVALNALVY
LYHKHLKQDLGDLGFRYATKQRQLPIVLSTEEVSEVLCQLNGRDQLIVQLLYGSGLRVSECLRLRIQDIDLARCSLTVRN
GKGHKDRQTILSQKCAIKLPAYIDAARAIQIKDNTYCIGPSLPNALERKYPNAFRQAGWMFVFPSTTTSDNPYTKTHCRH
HLHQSVIRKALAAAVRKTHIIKRVTCHTFRHSFATHLLQAGRDIRTIQELLGHNDVNTTQIYTHVLGQHYAGTVSPLDSL
>Mature_319_residues
AAIKSPFLTQVREHMRMRGYSIKTEKAYLYWIKAFINFQQKRHPETMGQAEVTQFLSFLANSRNVAINTQKVALNALVYL
YHKHLKQDLGDLGFRYATKQRQLPIVLSTEEVSEVLCQLNGRDQLIVQLLYGSGLRVSECLRLRIQDIDLARCSLTVRNG
KGHKDRQTILSQKCAIKLPAYIDAARAIQIKDNTYCIGPSLPNALERKYPNAFRQAGWMFVFPSTTTSDNPYTKTHCRHH
LHQSVIRKALAAAVRKTHIIKRVTCHTFRHSFATHLLQAGRDIRTIQELLGHNDVNTTQIYTHVLGQHYAGTVSPLDSL

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=26.1168384879725, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789261, Length=232, Percent_Identity=30.1724137931034, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36565; Mature: 36434

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIKSPFLTQVREHMRMRGYSIKTEKAYLYWIKAFINFQQKRHPETMGQAEVTQFLSFL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHH
ANSRNVAINTQKVALNALVYLYHKHLKQDLGDLGFRYATKQRQLPIVLSTEEVSEVLCQL
HCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHC
NGRDQLIVQLLYGSGLRVSECLRLRIQDIDLARCSLTVRNGKGHKDRQTILSQKCAIKLP
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHCEECC
AYIDAARAIQIKDNTYCIGPSLPNALERKYPNAFRQAGWMFVFPSTTTSDNPYTKTHCRH
HHHCCCEEEEECCCCEEECCCCCHHHHHHCCHHHHHCCCEEEECCCCCCCCCCHHHHHHH
HLHQSVIRKALAAAVRKTHIIKRVTCHTFRHSFATHLLQAGRDIRTIQELLGHNDVNTTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
IYTHVLGQHYAGTVSPLDSL
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AAIKSPFLTQVREHMRMRGYSIKTEKAYLYWIKAFINFQQKRHPETMGQAEVTQFLSFL
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHH
ANSRNVAINTQKVALNALVYLYHKHLKQDLGDLGFRYATKQRQLPIVLSTEEVSEVLCQL
HCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHC
NGRDQLIVQLLYGSGLRVSECLRLRIQDIDLARCSLTVRNGKGHKDRQTILSQKCAIKLP
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHCEECC
AYIDAARAIQIKDNTYCIGPSLPNALERKYPNAFRQAGWMFVFPSTTTSDNPYTKTHCRH
HHHCCCEEEEECCCCEEECCCCCHHHHHHCCHHHHHCCCEEEECCCCCCCCCCHHHHHHH
HLHQSVIRKALAAAVRKTHIIKRVTCHTFRHSFATHLLQAGRDIRTIQELLGHNDVNTTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
IYTHVLGQHYAGTVSPLDSL
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]