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The map label for this gene is 167623344

Identifier: 167623344

GI number: 167623344

Start: 1706418

End: 1707440

Strand: Direct

Name: 167623344

Synonym: Shal_1413

Alternate gene names: NA

Gene position: 1706418-1707440 (Clockwise)

Preceding gene: 167623343

Following gene: 167623345

Centisome position: 32.65

GC content: 44.67

Gene sequence:

>1023_bases
ATGATGCCTGCTAGCAAATCACAGTCCCCTATGCATTTTTGTGAACAACAGATCATTGAATTACTCAATGGCAACCAAGA
TGAATGGTTGTTTGCTAACGCTCAAGCGGTTACCCAACAGGTATTTGATAATCAGGTTTTTATCCGCGGTATAGTCGAGT
TCTCCAATCATTGTCGTCATAACTGCCATTATTGCGGGCTGCGCAGTAGTAACCGCCAAGTTGAACGTTATCGATTAAGC
GTCGATGAAATCCTCGATGCTGTCGATGACATTGCGCAATTTGGCATAGGAACAGTTGTTCTGCAATCAGGTGATGATTG
GCAATATCGCGCAGAGACAATCGCGGAACTTATTCGCACCATCAAAGAACGCCACAATTTAGCAATTACATTATCGCTAG
GTGACCGTAAGCACCAAGAGCTTAAACTTTGGCGCGAGGCGGGGGCAGATCGTTATTTGCTAAAAATGGAAACCTTTAAC
GAGCAACTATTTAATCAATGTAGGCCTAATGCCAACTTTGACGAGCGATTAGCACGCTTATCTTACATTCAATCTCTCGG
TTATCAAACTGGCTCGGGAGTCATAACAGACTTACCAGGAATGACCGATAAAATTCTTGCCACAGATATATTGAGGCTTT
CTGGCTTGGAGCTCGATATGTTGGCATGCGGCCCATTTGTCGCACACGCTCAAACCCCTTTTGCACAAAGTCCAAATGGC
GAGGTACTCAAAAGCCATCGGGTTAGTGCGATCTTGCGGCTAATGAATCCAGGTGCAAACATCCCGGCAACGAGTTCATT
GGAAGTCATTGAACTAGGTGCGCGAGAACTTGGACTTATGCGTGGCTGTAACGTTGTTATGCCCTCATTTACGCCCTCAC
AAGTCTATGCCAGTTATAACATTTATCCAGGTAAAAATAGCGCTACCAGTGATATTCAGCAAAGAGTAGCGGCCATATTT
CAACAAATACAACACCATGGCTTACAACCTAACGGTAGCCGTGGTGACTCAAGAAGGTATTAA

Upstream 100 bases:

>100_bases
GGCAACAGGTAATAAGTCGTTATGTGGATGAATGCCGCCAAGCTGCCCAATTTAGCTCAGCTACTACTCCCTCAACGTCC
AAATATTAAAGAAGACATTA

Downstream 100 bases:

>100_bases
TATGTGTCAAGGTGTTAACCCCGAAACCAGCCAAGGTCAAATAGCCCCCAGAGGGATGCGCTATCAAATTGCAATATTAG
GGAGGCGCAACGCTGGTAAA

Product: biotin synthase

Products: biotin

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MMPASKSQSPMHFCEQQIIELLNGNQDEWLFANAQAVTQQVFDNQVFIRGIVEFSNHCRHNCHYCGLRSSNRQVERYRLS
VDEILDAVDDIAQFGIGTVVLQSGDDWQYRAETIAELIRTIKERHNLAITLSLGDRKHQELKLWREAGADRYLLKMETFN
EQLFNQCRPNANFDERLARLSYIQSLGYQTGSGVITDLPGMTDKILATDILRLSGLELDMLACGPFVAHAQTPFAQSPNG
EVLKSHRVSAILRLMNPGANIPATSSLEVIELGARELGLMRGCNVVMPSFTPSQVYASYNIYPGKNSATSDIQQRVAAIF
QQIQHHGLQPNGSRGDSRRY

Sequences:

>Translated_340_residues
MMPASKSQSPMHFCEQQIIELLNGNQDEWLFANAQAVTQQVFDNQVFIRGIVEFSNHCRHNCHYCGLRSSNRQVERYRLS
VDEILDAVDDIAQFGIGTVVLQSGDDWQYRAETIAELIRTIKERHNLAITLSLGDRKHQELKLWREAGADRYLLKMETFN
EQLFNQCRPNANFDERLARLSYIQSLGYQTGSGVITDLPGMTDKILATDILRLSGLELDMLACGPFVAHAQTPFAQSPNG
EVLKSHRVSAILRLMNPGANIPATSSLEVIELGARELGLMRGCNVVMPSFTPSQVYASYNIYPGKNSATSDIQQRVAAIF
QQIQHHGLQPNGSRGDSRRY
>Mature_340_residues
MMPASKSQSPMHFCEQQIIELLNGNQDEWLFANAQAVTQQVFDNQVFIRGIVEFSNHCRHNCHYCGLRSSNRQVERYRLS
VDEILDAVDDIAQFGIGTVVLQSGDDWQYRAETIAELIRTIKERHNLAITLSLGDRKHQELKLWREAGADRYLLKMETFN
EQLFNQCRPNANFDERLARLSYIQSLGYQTGSGVITDLPGMTDKILATDILRLSGLELDMLACGPFVAHAQTPFAQSPNG
EVLKSHRVSAILRLMNPGANIPATSSLEVIELGARELGLMRGCNVVMPSFTPSQVYASYNIYPGKNSATSDIQQRVAAIF
QQIQHHGLQPNGSRGDSRRY

Specific function: Unknown

COG id: COG0502

COG function: function code H; Biotin synthase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR010722
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06968 BATS; PF04055 Radical_SAM [H]

EC number: 2.8.1.6

Molecular weight: Translated: 38216; Mature: 38216

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPASKSQSPMHFCEQQIIELLNGNQDEWLFANAQAVTQQVFDNQVFIRGIVEFSNHCRH
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCC
NCHYCGLRSSNRQVERYRLSVDEILDAVDDIAQFGIGTVVLQSGDDWQYRAETIAELIRT
CCEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
IKERHNLAITLSLGDRKHQELKLWREAGADRYLLKMETFNEQLFNQCRPNANFDERLARL
HHHHCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
SYIQSLGYQTGSGVITDLPGMTDKILATDILRLSGLELDMLACGPFVAHAQTPFAQSPNG
HHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCEEHHHCCCHHHHCCCCCCCCCCH
EVLKSHRVSAILRLMNPGANIPATSSLEVIELGARELGLMRGCNVVMPSFTPSQVYASYN
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCHHHHHHHHCCCEEECCCCHHHHEEEEE
IYPGKNSATSDIQQRVAAIFQQIQHHGLQPNGSRGDSRRY
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMPASKSQSPMHFCEQQIIELLNGNQDEWLFANAQAVTQQVFDNQVFIRGIVEFSNHCRH
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCC
NCHYCGLRSSNRQVERYRLSVDEILDAVDDIAQFGIGTVVLQSGDDWQYRAETIAELIRT
CCEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
IKERHNLAITLSLGDRKHQELKLWREAGADRYLLKMETFNEQLFNQCRPNANFDERLARL
HHHHCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
SYIQSLGYQTGSGVITDLPGMTDKILATDILRLSGLELDMLACGPFVAHAQTPFAQSPNG
HHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCEEHHHCCCHHHHCCCCCCCCCCH
EVLKSHRVSAILRLMNPGANIPATSSLEVIELGARELGLMRGCNVVMPSFTPSQVYASYN
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCHHHHHHHHCCCEEECCCCHHHHEEEEE
IYPGKNSATSDIQQRVAAIFQQIQHHGLQPNGSRGDSRRY
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dethiobiotin; sulfur

Specific reaction: dethiobiotin + sulfur = biotin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]