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The map label for this gene is hlyB [H]

Identifier: 167623306

GI number: 167623306

Start: 1651426

End: 1653051

Strand: Reverse

Name: hlyB [H]

Synonym: Shal_1374

Alternate gene names: 167623306

Gene position: 1653051-1651426 (Counterclockwise)

Preceding gene: 167623307

Following gene: 167623295

Centisome position: 31.63

GC content: 44.22

Gene sequence:

>1626_bases
ATGAAAACTCAGCTCACAATTAGAAAAAAGATAATCATGATGGTTGCGCTCATCTTGACGCTTATTACAGTTTGCGGCAG
CTACACCTTTTACTCCATATATCCCCTTTCCAAAAGCTGGAGCAGTTATCAAGAGCAAGTCTCCATGCGCCAACAGCTAT
TGATGAGTATTAAGGCAAACTTTGGCTATGGCGGAATGATCCACAATTTCAAGAACTATGTTTTGCGAGGACAAGATAAG
TACCTACCAAAAATAGAAAATGACTTCAAAAACCTACTCGATGATATTGCAAAGTACCAGCTACTTGAAGGCGTAAGCCC
ACAAGAAAGCAAGGCTCTAGATTCAATCACTGAAGTTGCTAGTAACTATTATTCAAACAGCAAACGTATTAGTCATTTTT
TTGCTGACGGGGAGTCACCACAATATGTCGATTCAGTAGCGAAGATAAGCGACAAGGCTGCATTAGAAGGCTTTGAAGTG
CTCGATAAACATTATCAAGCACTCACACAGGAATACAGTTCGCGGATCAATGGAGCGATTAGCTCGGCGACAATGGCTAC
CGTTACCGGGCTCTTGCTGGTTGCATTGGTTATTACGTTTGTGCTGTTATGGCTTTATCGCTCACTTATTCCTCCACTAC
TGACACTCAATCAAACGATGACAGAGATAGCTGAAGGTGAAGGCGATCTTAGCGTAAGAATAGAGGTGGAAAAAGATGAC
GAATTAGGTGGCGTTGCCAAAGCATTTAACCTGTTCGTATCTAAGCTCGAAGTGATTATCGCCGAAGAAAAGAAGATTAT
CGCTCAGATAAACTCCAGCGCCGAAGACTTACAAGAAGTCACGCAAAGCAGTAACAGTGCCATTGAATCTCAACTCAGTA
ATACCGAGATGCTTGCCACCGCGATTAATGAGATGACAGCGACGGTTCAAGACGTTGCAGAAAATGCCGTGATGGCGTCA
GACGCCGCAGTAAAGGTTAATACCAGCGCCCATGAGGGGCATAGGGCTGTCAACAATACGGTAGAACAGATCCTTAATGT
ACACCAGCATATCGACCAAGCATCAAACGTGATCCACGAAGTGAACAAGGCATCAGAAAATATCGATCAGGTACTAAACG
TCATATCGGGTATTGCCCAACAAACCAATCTTTTAGCATTGAATGCTGCCATCGAAGCAGCTAGAGCCGGTGAATCAGGA
CGCGGTTTCGCCGTGGTTGCCGATGAAGTTAGGGGATTAGCACAGAGAACCTCAACCTCGCTTGAGGATATCAAGCAGAT
AATTGAGCAGTTGCAAACCGGTGCCAATAGCGCTGTCGCGTCAATAGAGCTTGGTGTAAATGAAGCATCTAACGCCTCTG
AAATCGCTAGAGTTGCAGGCACAAGCATCGATGGCATCGTTGAATCAATTCAATCGGTTGAGAGTATGAACTTGCAAATA
GCGACGGCAACAGAGGAACAAAATACCGTTGCCGAAGAGATGAACAAAAGTGTACACGATATCTCGACCATGACGTCATC
AATTTATGATGGTTCGCAGCAGATCTCAAAGCAGAGCCATAATTTAGCGCAGACGACCAAGAGGTTAAAACAGCTAGTTG
GCAGCTTTAAGACTCAAGTTAGTTAA

Upstream 100 bases:

>100_bases
TTAATATGGCTCCTGTGTAAAACAGGTATTTACAGATAATTTAAACATTTACATTTCACCGCCTCTTAGTCTCCCCCAAG
AGATATACAAAAGGACTTGT

Downstream 100 bases:

>100_bases
TGACGTTAGGTTCAAACTTCATTTGAAGAGTTTTGCCCCAAAGCAGCTTAACCTTTGAGTGAAGCTTGGTTACATTCATT
CTTGGGGTGGTGCTACATAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKTQLTIRKKIIMMVALILTLITVCGSYTFYSIYPLSKSWSSYQEQVSMRQQLLMSIKANFGYGGMIHNFKNYVLRGQDK
YLPKIENDFKNLLDDIAKYQLLEGVSPQESKALDSITEVASNYYSNSKRISHFFADGESPQYVDSVAKISDKAALEGFEV
LDKHYQALTQEYSSRINGAISSATMATVTGLLLVALVITFVLLWLYRSLIPPLLTLNQTMTEIAEGEGDLSVRIEVEKDD
ELGGVAKAFNLFVSKLEVIIAEEKKIIAQINSSAEDLQEVTQSSNSAIESQLSNTEMLATAINEMTATVQDVAENAVMAS
DAAVKVNTSAHEGHRAVNNTVEQILNVHQHIDQASNVIHEVNKASENIDQVLNVISGIAQQTNLLALNAAIEAARAGESG
RGFAVVADEVRGLAQRTSTSLEDIKQIIEQLQTGANSAVASIELGVNEASNASEIARVAGTSIDGIVESIQSVESMNLQI
ATATEEQNTVAEEMNKSVHDISTMTSSIYDGSQQISKQSHNLAQTTKRLKQLVGSFKTQVS

Sequences:

>Translated_541_residues
MKTQLTIRKKIIMMVALILTLITVCGSYTFYSIYPLSKSWSSYQEQVSMRQQLLMSIKANFGYGGMIHNFKNYVLRGQDK
YLPKIENDFKNLLDDIAKYQLLEGVSPQESKALDSITEVASNYYSNSKRISHFFADGESPQYVDSVAKISDKAALEGFEV
LDKHYQALTQEYSSRINGAISSATMATVTGLLLVALVITFVLLWLYRSLIPPLLTLNQTMTEIAEGEGDLSVRIEVEKDD
ELGGVAKAFNLFVSKLEVIIAEEKKIIAQINSSAEDLQEVTQSSNSAIESQLSNTEMLATAINEMTATVQDVAENAVMAS
DAAVKVNTSAHEGHRAVNNTVEQILNVHQHIDQASNVIHEVNKASENIDQVLNVISGIAQQTNLLALNAAIEAARAGESG
RGFAVVADEVRGLAQRTSTSLEDIKQIIEQLQTGANSAVASIELGVNEASNASEIARVAGTSIDGIVESIQSVESMNLQI
ATATEEQNTVAEEMNKSVHDISTMTSSIYDGSQQISKQSHNLAQTTKRLKQLVGSFKTQVS
>Mature_541_residues
MKTQLTIRKKIIMMVALILTLITVCGSYTFYSIYPLSKSWSSYQEQVSMRQQLLMSIKANFGYGGMIHNFKNYVLRGQDK
YLPKIENDFKNLLDDIAKYQLLEGVSPQESKALDSITEVASNYYSNSKRISHFFADGESPQYVDSVAKISDKAALEGFEV
LDKHYQALTQEYSSRINGAISSATMATVTGLLLVALVITFVLLWLYRSLIPPLLTLNQTMTEIAEGEGDLSVRIEVEKDD
ELGGVAKAFNLFVSKLEVIIAEEKKIIAQINSSAEDLQEVTQSSNSAIESQLSNTEMLATAINEMTATVQDVAENAVMAS
DAAVKVNTSAHEGHRAVNNTVEQILNVHQHIDQASNVIHEVNKASENIDQVLNVISGIAQQTNLLALNAAIEAARAGESG
RGFAVVADEVRGLAQRTSTSLEDIKQIIEQLQTGANSAVASIELGVNEASNASEIARVAGTSIDGIVESIQSVESMNLQI
ATATEEQNTVAEEMNKSVHDISTMTSSIYDGSQQISKQSHNLAQTTKRLKQLVGSFKTQVS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=444, Percent_Identity=29.2792792792793, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1787690, Length=349, Percent_Identity=28.9398280802292, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788195, Length=304, Percent_Identity=30.5921052631579, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788194, Length=325, Percent_Identity=29.8461538461538, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789453, Length=320, Percent_Identity=25.3125, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59002; Mature: 59002

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQLTIRKKIIMMVALILTLITVCGSYTFYSIYPLSKSWSSYQEQVSMRQQLLMSIKAN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
FGYGGMIHNFKNYVLRGQDKYLPKIENDFKNLLDDIAKYQLLEGVSPQESKALDSITEVA
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SNYYSNSKRISHFFADGESPQYVDSVAKISDKAALEGFEVLDKHYQALTQEYSSRINGAI
HHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSATMATVTGLLLVALVITFVLLWLYRSLIPPLLTLNQTMTEIAEGEGDLSVRIEVEKDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
ELGGVAKAFNLFVSKLEVIIAEEKKIIAQINSSAEDLQEVTQSSNSAIESQLSNTEMLAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINEMTATVQDVAENAVMASDAAVKVNTSAHEGHRAVNNTVEQILNVHQHIDQASNVIHE
HHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNKASENIDQVLNVISGIAQQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQRTSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCC
LEDIKQIIEQLQTGANSAVASIELGVNEASNASEIARVAGTSIDGIVESIQSVESMNLQI
HHHHHHHHHHHHCCCCHHHEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEE
ATATEEQNTVAEEMNKSVHDISTMTSSIYDGSQQISKQSHNLAQTTKRLKQLVGSFKTQV
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure
MKTQLTIRKKIIMMVALILTLITVCGSYTFYSIYPLSKSWSSYQEQVSMRQQLLMSIKAN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
FGYGGMIHNFKNYVLRGQDKYLPKIENDFKNLLDDIAKYQLLEGVSPQESKALDSITEVA
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SNYYSNSKRISHFFADGESPQYVDSVAKISDKAALEGFEVLDKHYQALTQEYSSRINGAI
HHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSATMATVTGLLLVALVITFVLLWLYRSLIPPLLTLNQTMTEIAEGEGDLSVRIEVEKDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
ELGGVAKAFNLFVSKLEVIIAEEKKIIAQINSSAEDLQEVTQSSNSAIESQLSNTEMLAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINEMTATVQDVAENAVMASDAAVKVNTSAHEGHRAVNNTVEQILNVHQHIDQASNVIHE
HHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNKASENIDQVLNVISGIAQQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQRTSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCC
LEDIKQIIEQLQTGANSAVASIELGVNEASNASEIARVAGTSIDGIVESIQSVESMNLQI
HHHHHHHHHHHHCCCCHHHEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEE
ATATEEQNTVAEEMNKSVHDISTMTSSIYDGSQQISKQSHNLAQTTKRLKQLVGSFKTQV
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]