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The map label for this gene is engA

Identifier: 167623303

GI number: 167623303

Start: 1646388

End: 1647860

Strand: Direct

Name: engA

Synonym: Shal_1371

Alternate gene names: 167623303

Gene position: 1646388-1647860 (Clockwise)

Preceding gene: 167623302

Following gene: 167623304

Centisome position: 31.5

GC content: 48.2

Gene sequence:

>1473_bases
ATGATTCCTGTTGTGGCCCTTGTAGGGCGACCAAACGTTGGTAAGTCGACCCTTTTTAACCGACTTACCCGTACTAGAGA
TGCGCTTGTCGCTGACTTTCCTGGGCTAACTCGGGATCGTAAATACGGCCGAGCACATCTTGCAGGTTATGAGTTTATCG
TAGTTGATACTGGCGGTATCGACGGCACCGAAGAAGGGATTGAAACTCGCATGGCCGAGCAATCTCTAGCGGCAATTGAA
GAAGCGGATGTTGTGCTGTTTCTTACCGATGCCCGTGCTGGTCTAACTGCTGCCGATCTTGCGATTGCTCAACATTTACG
TAGCCGTGAAAAAACCACCTTTGTTGTTGCTAACAAGGTTGATGGTATCGATGCGGATTCAGCTTGTGCCGAATTTTGGT
CATTAGGTCTAGGTGAAGTTTACCAAATGGCTGCGGCTCAGGGCCGCGGCGTGACCAACATGATCGAGTATTCTTTAGCG
CCATACGCAGAAGCGATGGGTATCGTTAAGCAAGAAGACGGTGATGATGACGAAGAAGAGCGTGAGTTCACCGAAGAAGA
AGCGGAAGCTGAGCAGAAACGTCTGCAAGACTTGCCAATTAAGCTTGCTATCATTGGTAAGCCAAACGTAGGTAAGTCAA
CGTTAACTAACCGTATCTTAGGTGAAGAGCGCGTTGTAGTTTATGACGAGCCTGGCACGACTCGCGACAGTATTTACATT
CCTATGGAACGTCAAGGCCGTGAGTACGTATTGATTGACACCGCAGGTGTTCGTCGTCGTAGCAAGGTGCATGAAACCGT
TGAGAAATTCTCGGTGATTAAGACCCTTAAAGCGGTTGAAGACAGTAACGTGGTATTGCTGGTTATCGATGCCCGTGAAG
GTATTGCTGAGCAAGACTTAGGTCTATTAGGTTTCGTGCTAAACGCGGGCCGCGCATTGGTTATTGCCGTTAACAAGTGG
GACGGTATTGATCAGAATGTTAAAGACAGAGTGAAGACTGAACTTGATCGCCGTTTAGGCTTTATCGATTTCGCCCGTAT
TCACTTTATCTCTGCACTGCACGGTACTGGTGTGGGTCACTTGTTTGAGTCAATCGAAGAAGCGTATGACAGTGCGACGC
GCCGTGTAAGTACATCAATGCTGACTCGTATCATGCAGATGTCTCAAGACGATCACCAGCCACCGTTGGTTAACGGTCGC
CGTGTTAAGCTTAAATACGCTCACGCTGGTGGTTACAACCCTCCAATCGTGGTTGTACACGGTAACCAGGTTAAGAAGCT
TCCAGACTCTTACAAGCGTTATATGATGAACTACTTCCGTCGTTCATTGAAGGTGATTGGTACGCCAATCCAGTTACGCT
TCCAAGAAGGTGGCAACCCGTTTGAGGGCTTGAACACCAAGAAGCTTACTGTGAGCCAAGAGCGACGTCGTAAGCGTATG
GTTGGCCATATTCGCGATAAGAATAAGGATTAA

Upstream 100 bases:

>100_bases
GTAACACTTCCGTAAGCCAAGTCGTTAGAGATGATAAGGCCCCTGGATGTGTATCTGGGGGCTTTTTAGTTATTAGAAAT
AGAGTAATAGAGGCAATTAA

Downstream 100 bases:

>100_bases
CTCTTTTGCTGATTAGCAAATAGTTAAAGTAATTTACAAAAGGAACCTCAGGGTTCCTTTTTTGTTTATATATTGAGTTG
ATTTTAATTTGTTATTTTTA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGIDGTEEGIETRMAEQSLAAIE
EADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLA
PYAEAMGIVKQEDGDDDEEEREFTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDLGLLGFVLNAGRALVIAVNKW
DGIDQNVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGR
RVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGLNTKKLTVSQERRRKRM
VGHIRDKNKD

Sequences:

>Translated_490_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGIDGTEEGIETRMAEQSLAAIE
EADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLA
PYAEAMGIVKQEDGDDDEEEREFTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDLGLLGFVLNAGRALVIAVNKW
DGIDQNVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGR
RVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGLNTKKLTVSQERRRKRM
VGHIRDKNKD
>Mature_490_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGIDGTEEGIETRMAEQSLAAIE
EADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLA
PYAEAMGIVKQEDGDDDEEEREFTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDLGLLGFVLNAGRALVIAVNKW
DGIDQNVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGR
RVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGLNTKKLTVSQERRRKRM
VGHIRDKNKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=494, Percent_Identity=72.2672064777328, Blast_Score=720, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=103, Percent_Identity=36.8932038834951, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=32.6388888888889, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SHEHH (B0TLI8)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673597.1
- ProteinModelPortal:   B0TLI8
- SMR:   B0TLI8
- GeneID:   5906952
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1371
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   SHAL458817:SHAL_1371-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54730; Mature: 54730

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCEEEEEEECCCC
DGTEEGIETRMAEQSLAAIEEADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKV
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
DGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLAPYAEAMGIVKQEDGDDDEEE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCHHH
REFTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEE
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDL
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
GLLGFVLNAGRALVIAVNKWDGIDQNVKDRVKTELDRRLGFIDFARIHFISALHGTGVGH
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
LFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEE
GNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGLNTKKLTVSQERRRKRM
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCHHHHHHHH
VGHIRDKNKD
HHHHHCCCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCEEEEEEECCCC
DGTEEGIETRMAEQSLAAIEEADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKV
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
DGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLAPYAEAMGIVKQEDGDDDEEE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCHHH
REFTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEE
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDL
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
GLLGFVLNAGRALVIAVNKWDGIDQNVKDRVKTELDRRLGFIDFARIHFISALHGTGVGH
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
LFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEE
GNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGLNTKKLTVSQERRRKRM
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCHHHHHHHH
VGHIRDKNKD
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA