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The map label for this gene is aceB [H]

Identifier: 167623284

GI number: 167623284

Start: 1626595

End: 1628232

Strand: Direct

Name: aceB [H]

Synonym: Shal_1352

Alternate gene names: 167623284

Gene position: 1626595-1628232 (Clockwise)

Preceding gene: 167623283

Following gene: 167623285

Centisome position: 31.12

GC content: 46.83

Gene sequence:

>1638_bases
ATGACGGAGCAATTAACTGCACTAGAGAGCTCAGATACATTGGTGTCGAGTCAAGAGTTACAGATTAATGGGTCTGCAGT
GGCAGGCCAAGAGCAGGTGCTGACAGAGGGCACATTGTGTTTGCTTAAGGCCTTATGCAAGCAGTTTGCCGCAGAGGTGC
CCAATTTGCTTGCCAATAGACAGGCTAAGCAAAAGCGTATCGATTCAGGCGAGTTGCCTGATTTTCTAGAAGAGACTCAA
GCGCTGCGTCAGCGAGATTGGCTGATCCGCGGCATTCCCCAAGACTTACAAGATAGACGCGTCGAGATCACTGGCCCTGT
TGAAAGAAAAATGGTCATTAATGCGCTTAATGCAAATGCCAAAGTATTTATGGCTGACTTTGAAGATTCACTTGCTCCAA
GCTGGCAAAAAATCGTGCAAGGACAAATAAACCTGCGTGATGCAGTTAACGGCGACATTAGCTATATCGCAACGGAAACT
GGCAAGCATTACTCGCTAAATGATAATCCCGCAGTGCTCATCTGCCGAGTGCGTGGTTTACATATGTTGGAGCAGCATGT
GCAGTTTGGTGGGGTCGCAATTCCAGCGAGCTTGTTTGATTTTTGCGTCTATTTCTACAATAACTACCGCAAGTTATTGA
GTAAAGGCAGCGGGCCTTACTTTTATATCCCTAAACTTGAAAGTCATCTTGAGGCTAGATGGTGGGCTAAGGTATTTGCA
TTTGTTGAGGAGCGGTTTTGCCTGCAGCCCGGTACGATAAAGTGTACCTGTTTAATTGAAACTCTTCCGGCTGTGTTTGA
GATGGATGAGATCTTATATGAACTGCGCTCTAACATTGTTGCACTGAACTGCGGTCGTTGGGATTATATTTTTAGCTATA
TTAAAACTCTAAATAACCATAGCGACAGGGTGTTGCCCGATAGACAGTCGGTCACCATGGATAAGCCATTCTTGAGTGCT
TATTCTCGTTTGTTGATTAAAACCTGTCATAAGCGTGGCGCCTTAGCCATGGGGGGGATGGCGGCCTTTATTCCATCAAA
GGATGCCGAGATTAACCAGCAAGTGCTAGATAAGGTTAAGCAAGATAAGCAGTTAGAAGCGCGTAATGGTCATGATGGTA
CTTGGGTTGCTCACCCGGGACTTGCCGATACTGCGATGGCCATTTTTAACGAATACATAGGTGAAGATCATATTAATCAA
CTACACATCACTCGTGACGTTGATGCTCCTATTCACGCCAGAGAACTACTCAAGCCCGCAAAGGGGGAGTGCACAGAAGC
GGGCATGCGCCTCAACATTCGAATTGCACTGCAATATATCGAGTCTTGGATTAATGGCAACGGCTGTGTGCCTATTTACG
GCTTGATGGAAGATGCCGCCACTGCAGAGATATCTCGTACATCTATTTGGCAGTGGATAAAGCACCTGCAGCCGCTTAGC
TCTGGCGCAATTGTGACTAAAGGCTTGTTTCAAGAGATGTTGGTAGAGGAGCTCGCCCACGTTAAAGACGAGGTCGGTGC
AGACCGTTTTACCCATGGCAGTTTTACTCAGGCTGCGGTTCTGTTAGAGCAGATCACCACTTCAGACGAGCTGGTCGACT
TCTTAACGGAGCCGGGATATCAAATACTGGTGGAGTAA

Upstream 100 bases:

>100_bases
TGTGAATATTTTGAGTCTTCAAAGCTTGAACGCTGACGACCTAATGCTGCCAATGCTAGGTGTCATCAAGGATATGGAAA
AGTTTTAGGAGATATAAAAG

Downstream 100 bases:

>100_bases
AACCTGCCTTGCAAAAGTTTGGCTGCATTTTGTAGCTTGTGTCCCCCGCACAGTATTCCTACGTGCTGTGCGGGTTTTTA
AATTATTAACACTACACTCT

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTEQLTALESSDTLVSSQELQINGSAVAGQEQVLTEGTLCLLKALCKQFAAEVPNLLANRQAKQKRIDSGELPDFLEETQ
ALRQRDWLIRGIPQDLQDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWQKIVQGQINLRDAVNGDISYIATET
GKHYSLNDNPAVLICRVRGLHMLEQHVQFGGVAIPASLFDFCVYFYNNYRKLLSKGSGPYFYIPKLESHLEARWWAKVFA
FVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNHSDRVLPDRQSVTMDKPFLSA
YSRLLIKTCHKRGALAMGGMAAFIPSKDAEINQQVLDKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQ
LHITRDVDAPIHARELLKPAKGECTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQWIKHLQPLS
SGAIVTKGLFQEMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTSDELVDFLTEPGYQILVE

Sequences:

>Translated_545_residues
MTEQLTALESSDTLVSSQELQINGSAVAGQEQVLTEGTLCLLKALCKQFAAEVPNLLANRQAKQKRIDSGELPDFLEETQ
ALRQRDWLIRGIPQDLQDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWQKIVQGQINLRDAVNGDISYIATET
GKHYSLNDNPAVLICRVRGLHMLEQHVQFGGVAIPASLFDFCVYFYNNYRKLLSKGSGPYFYIPKLESHLEARWWAKVFA
FVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNHSDRVLPDRQSVTMDKPFLSA
YSRLLIKTCHKRGALAMGGMAAFIPSKDAEINQQVLDKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQ
LHITRDVDAPIHARELLKPAKGECTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQWIKHLQPLS
SGAIVTKGLFQEMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTSDELVDFLTEPGYQILVE
>Mature_544_residues
TEQLTALESSDTLVSSQELQINGSAVAGQEQVLTEGTLCLLKALCKQFAAEVPNLLANRQAKQKRIDSGELPDFLEETQA
LRQRDWLIRGIPQDLQDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWQKIVQGQINLRDAVNGDISYIATETG
KHYSLNDNPAVLICRVRGLHMLEQHVQFGGVAIPASLFDFCVYFYNNYRKLLSKGSGPYFYIPKLESHLEARWWAKVFAF
VEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNHSDRVLPDRQSVTMDKPFLSAY
SRLLIKTCHKRGALAMGGMAAFIPSKDAEINQQVLDKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQL
HITRDVDAPIHARELLKPAKGECTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQWIKHLQPLSS
GAIVTKGLFQEMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTSDELVDFLTEPGYQILVE

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=543, Percent_Identity=66.1141804788214, Blast_Score=739, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=538, Percent_Identity=46.6542750929368, Blast_Score=472, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI71982926, Length=431, Percent_Identity=48.0278422273782, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322222, Length=522, Percent_Identity=43.4865900383142, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6324212, Length=476, Percent_Identity=46.6386554621849, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 61278; Mature: 61147

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQLTALESSDTLVSSQELQINGSAVAGQEQVLTEGTLCLLKALCKQFAAEVPNLLANR
CCCHHHHCCCCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QAKQKRIDSGELPDFLEETQALRQRDWLIRGIPQDLQDRRVEITGPVERKMVINALNANA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCHHHHHHHHHCCCCC
KVFMADFEDSLAPSWQKIVQGQINLRDAVNGDISYIATETGKHYSLNDNPAVLICRVRGL
EEEEECCCHHCCHHHHHHHCCCCCCHHCCCCCEEEEEECCCCEEECCCCCEEEEEEHHHH
HMLEQHVQFGGVAIPASLFDFCVYFYNNYRKLLSKGSGPYFYIPKLESHLEARWWAKVFA
HHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHH
FVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNH
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCC
SDRVLPDRQSVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPSKDAEINQQVLDKVK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCHHHHHHHHHHH
QDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQLHITRDVDAPIHARELLKPA
HCCHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCC
KGECTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQWIKHLQPLS
CCCHHHCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGAIVTKGLFQEMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTSDELVDFLTEPGY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC
QILVE
EEEEC
>Mature Secondary Structure 
TEQLTALESSDTLVSSQELQINGSAVAGQEQVLTEGTLCLLKALCKQFAAEVPNLLANR
CCHHHHCCCCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QAKQKRIDSGELPDFLEETQALRQRDWLIRGIPQDLQDRRVEITGPVERKMVINALNANA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCHHHHHHHHHCCCCC
KVFMADFEDSLAPSWQKIVQGQINLRDAVNGDISYIATETGKHYSLNDNPAVLICRVRGL
EEEEECCCHHCCHHHHHHHCCCCCCHHCCCCCEEEEEECCCCEEECCCCCEEEEEEHHHH
HMLEQHVQFGGVAIPASLFDFCVYFYNNYRKLLSKGSGPYFYIPKLESHLEARWWAKVFA
HHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHH
FVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNH
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCC
SDRVLPDRQSVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPSKDAEINQQVLDKVK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCHHHHHHHHHHH
QDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQLHITRDVDAPIHARELLKPA
HCCHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCC
KGECTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQWIKHLQPLS
CCCHHHCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGAIVTKGLFQEMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTSDELVDFLTEPGY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC
QILVE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]