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The map label for this gene is yegE [H]

Identifier: 167623283

GI number: 167623283

Start: 1623942

End: 1625750

Strand: Direct

Name: yegE [H]

Synonym: Shal_1351

Alternate gene names: 167623283

Gene position: 1623942-1625750 (Clockwise)

Preceding gene: 167623282

Following gene: 167623284

Centisome position: 31.07

GC content: 41.74

Gene sequence:

>1809_bases
ATGCCAATAAGAAGTAACACGATAATGAACTGGGTTTCCATCGTGGGGCTCTTTTTTTGTTTAGCATTTCCTCTAGCGGG
AAATGCTAACGATGAATCTTATGATGAAACTTTAAATAAGCTTGATAAAGCAAGTAGCTCTTCCCAAGTAGAGGCAGAAG
CTATTATTGAATCCTTGTTAACTTCTTGGACAGAGCTTTCAAATGAACAAAAGGCTAGATTAAAAATGTATATAGCTATA
GGGAAAACCTATGCTGGGGATTATCATCCCTCTATACAACTTTTAAGAGAAGCCGAGCAACTTACCCCAAGCACTGCAAC
ACTTAACAAAATTTATCAATACTTATCCACAAATTATATTGCTTTAAAAGATTATCCCGCTGCTCTAGCACTAATGACCG
CAAACTTAGAGCGCATAGATGAAATAACCGATATTGATATTAAGATGGGATCATACGTACGCTTGGCAAATCTGGCGCTG
GCACTGGATGCTTATGACGATATGCGCGAGTATGCCTTAAAAGCCTTGGCGCTTAGTCAAGATGGTGAAGCTAGAGTGCA
TTGTTTCGCATTATTGTTTGTTGCGGTTGCCGATTTAAAGCAACAACAATATAAAAGTTCTGAGAGCCGTTTTCAACGTA
GTAAGATTTTTTGTGAGGCCAATCAATTCCCGCTGATTGGCTTGATGTCTCAAAAAGGATTAGCCGAAATCGCTATCCAA
GGTGAGGATTATAAGAGGGCTAAAAGCCTGTTAGAGCTAGTGTTAAAAGCCTATCAAGAATTTAATTTTCAAACTGAAAT
CAATCATGTTAATGCACTATTGAGTCAAACTTACCTTGCGTTAGAAGATTACCCCCAAGCGGAAGAGTTTGCGAATAAGG
TGATGGGGTTAAGTGATGACCCAAGTCACATCGAGTATAAAGCCATTGCCGCCAAAGTACTATCCCAGCTCTATTTAGAG
TCAAAGCAGTATAAGCTTGCCTATGACTATCTAGACTCTCATCAATATTATACTAACCTGATTATCGATGACACTAAAGC
CAAGGCTAACGCCTACCAGATGGCCAAGTTTAAACACCAAGAGCAGGCGCGCGAGATTGCCTTACTCAATCAGGAACGGC
AATTGGTGGAAACTCAGAAAGAGTTAGACCAATCTGACCGCACTAACGATGTCATGATCATGAGTATGTTGGTTGGCAGC
GTGATTTTCTTGTCGTTTTTTCTTATTAATAGTCACCGCCAAAAAATACGTTATCGTAAACTTGCATTAACCGATAGGCT
GACAGGCGCTTACAATCGTGGTGCAGGACAAGATTTTGCTGAAAATGAGTTTGTGCAGGTCAGCATGCGCCAAGCTGAAT
TCTCCGTAGTGGTATTTGATTTAGATCTATTTAAAAACATTAACGACGGTTACGGTCACGCAACGGGTGACTGGACGTTA
AAGCATGTGGTATCTGCTGTTAAACCGCTTATTCGTGACAGTGATATTTTTACTCGAATGGGCGGAGAAGAGTTTGCGCT
CTTTTTACCCTATTCAAGTGAAGAGGTCGCATTAGGCATCGCGCAGCGTTGTAAAGAGGCTATTGCTGCTATCGATAGTA
AGTACTCAGGGCATTCGTTTAAAGTCACTGCTAGTTTTGGCGTGTCGAGTAACAAACTTGAGGATCTCAGTCTAGACCCT
TTACTAAAACGTGCCGATATCGCGCTTTATACGTCCAAGCACTTAGGCCGCAATAGAGTGACGCTGTACACCCCTGAGCT
TGAGCTACAGTGCAGCAGCGAGACCCAGCGCTCACTCGTATTTAACTAG

Upstream 100 bases:

>100_bases
GGTCTAAGTGATGCTGAGATCCAAGCGGTGATGTCAGGTGATGATAGCAAGCTTAAGTCATTGTCGGGTGATAAGGGAAC
TAAAGGGTATTTGGTCGTTC

Downstream 100 bases:

>100_bases
GCTGCCTGTTATATCAGCTTAAAAACTTGCTAGTTATCTCGACAGGCTTAATTGAAGCTCAACAGATAATGTGGCAATAC
TTCGAGCCTGTAGCCTCTTC

Product: diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MPIRSNTIMNWVSIVGLFFCLAFPLAGNANDESYDETLNKLDKASSSSQVEAEAIIESLLTSWTELSNEQKARLKMYIAI
GKTYAGDYHPSIQLLREAEQLTPSTATLNKIYQYLSTNYIALKDYPAALALMTANLERIDEITDIDIKMGSYVRLANLAL
ALDAYDDMREYALKALALSQDGEARVHCFALLFVAVADLKQQQYKSSESRFQRSKIFCEANQFPLIGLMSQKGLAEIAIQ
GEDYKRAKSLLELVLKAYQEFNFQTEINHVNALLSQTYLALEDYPQAEEFANKVMGLSDDPSHIEYKAIAAKVLSQLYLE
SKQYKLAYDYLDSHQYYTNLIIDDTKAKANAYQMAKFKHQEQAREIALLNQERQLVETQKELDQSDRTNDVMIMSMLVGS
VIFLSFFLINSHRQKIRYRKLALTDRLTGAYNRGAGQDFAENEFVQVSMRQAEFSVVVFDLDLFKNINDGYGHATGDWTL
KHVVSAVKPLIRDSDIFTRMGGEEFALFLPYSSEEVALGIAQRCKEAIAAIDSKYSGHSFKVTASFGVSSNKLEDLSLDP
LLKRADIALYTSKHLGRNRVTLYTPELELQCSSETQRSLVFN

Sequences:

>Translated_602_residues
MPIRSNTIMNWVSIVGLFFCLAFPLAGNANDESYDETLNKLDKASSSSQVEAEAIIESLLTSWTELSNEQKARLKMYIAI
GKTYAGDYHPSIQLLREAEQLTPSTATLNKIYQYLSTNYIALKDYPAALALMTANLERIDEITDIDIKMGSYVRLANLAL
ALDAYDDMREYALKALALSQDGEARVHCFALLFVAVADLKQQQYKSSESRFQRSKIFCEANQFPLIGLMSQKGLAEIAIQ
GEDYKRAKSLLELVLKAYQEFNFQTEINHVNALLSQTYLALEDYPQAEEFANKVMGLSDDPSHIEYKAIAAKVLSQLYLE
SKQYKLAYDYLDSHQYYTNLIIDDTKAKANAYQMAKFKHQEQAREIALLNQERQLVETQKELDQSDRTNDVMIMSMLVGS
VIFLSFFLINSHRQKIRYRKLALTDRLTGAYNRGAGQDFAENEFVQVSMRQAEFSVVVFDLDLFKNINDGYGHATGDWTL
KHVVSAVKPLIRDSDIFTRMGGEEFALFLPYSSEEVALGIAQRCKEAIAAIDSKYSGHSFKVTASFGVSSNKLEDLSLDP
LLKRADIALYTSKHLGRNRVTLYTPELELQCSSETQRSLVFN
>Mature_601_residues
PIRSNTIMNWVSIVGLFFCLAFPLAGNANDESYDETLNKLDKASSSSQVEAEAIIESLLTSWTELSNEQKARLKMYIAIG
KTYAGDYHPSIQLLREAEQLTPSTATLNKIYQYLSTNYIALKDYPAALALMTANLERIDEITDIDIKMGSYVRLANLALA
LDAYDDMREYALKALALSQDGEARVHCFALLFVAVADLKQQQYKSSESRFQRSKIFCEANQFPLIGLMSQKGLAEIAIQG
EDYKRAKSLLELVLKAYQEFNFQTEINHVNALLSQTYLALEDYPQAEEFANKVMGLSDDPSHIEYKAIAAKVLSQLYLES
KQYKLAYDYLDSHQYYTNLIIDDTKAKANAYQMAKFKHQEQAREIALLNQERQLVETQKELDQSDRTNDVMIMSMLVGSV
IFLSFFLINSHRQKIRYRKLALTDRLTGAYNRGAGQDFAENEFVQVSMRQAEFSVVVFDLDLFKNINDGYGHATGDWTLK
HVVSAVKPLIRDSDIFTRMGGEEFALFLPYSSEEVALGIAQRCKEAIAAIDSKYSGHSFKVTASFGVSSNKLEDLSLDPL
LKRADIALYTSKHLGRNRVTLYTPELELQCSSETQRSLVFN

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=174, Percent_Identity=33.9080459770115, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=37.9518072289157, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081881, Length=156, Percent_Identity=36.5384615384615, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=32.5301204819277, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786584, Length=189, Percent_Identity=28.042328042328, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1787802, Length=187, Percent_Identity=31.5508021390374, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=34.5454545454545, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=29.7142857142857, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787816, Length=135, Percent_Identity=32.5925925925926, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788085, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=176, Percent_Identity=27.8409090909091, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 68121; Mature: 67990

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRSNTIMNWVSIVGLFFCLAFPLAGNANDESYDETLNKLDKASSSSQVEAEAIIESLL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TSWTELSNEQKARLKMYIAIGKTYAGDYHPSIQLLREAEQLTPSTATLNKIYQYLSTNYI
HHHHHHCCCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEE
ALKDYPAALALMTANLERIDEITDIDIKMGSYVRLANLALALDAYDDMREYALKALALSQ
EEECCCHHHHHHHHCHHHHHHHCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
DGEARVHCFALLFVAVADLKQQQYKSSESRFQRSKIFCEANQFPLIGLMSQKGLAEIAIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEC
GEDYKRAKSLLELVLKAYQEFNFQTEINHVNALLSQTYLALEDYPQAEEFANKVMGLSDD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
PSHIEYKAIAAKVLSQLYLESKQYKLAYDYLDSHQYYTNLIIDDTKAKANAYQMAKFKHQ
CCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHH
EQAREIALLNQERQLVETQKELDQSDRTNDVMIMSMLVGSVIFLSFFLINSHRQKIRYRK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTDRLTGAYNRGAGQDFAENEFVQVSMRQAEFSVVVFDLDLFKNINDGYGHATGDWTL
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEHHHHHCCCCCCCCCCCCHHH
KHVVSAVKPLIRDSDIFTRMGGEEFALFLPYSSEEVALGIAQRCKEAIAAIDSKYSGHSF
HHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
KVTASFGVSSNKLEDLSLDPLLKRADIALYTSKHLGRNRVTLYTPELELQCSSETQRSLV
EEEEECCCCCCCCCCCCCCHHHHHCCEEEEEHHCCCCCCEEEECCCEEEEECCCCCCCCC
FN
CC
>Mature Secondary Structure 
PIRSNTIMNWVSIVGLFFCLAFPLAGNANDESYDETLNKLDKASSSSQVEAEAIIESLL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TSWTELSNEQKARLKMYIAIGKTYAGDYHPSIQLLREAEQLTPSTATLNKIYQYLSTNYI
HHHHHHCCCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEE
ALKDYPAALALMTANLERIDEITDIDIKMGSYVRLANLALALDAYDDMREYALKALALSQ
EEECCCHHHHHHHHCHHHHHHHCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
DGEARVHCFALLFVAVADLKQQQYKSSESRFQRSKIFCEANQFPLIGLMSQKGLAEIAIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEC
GEDYKRAKSLLELVLKAYQEFNFQTEINHVNALLSQTYLALEDYPQAEEFANKVMGLSDD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
PSHIEYKAIAAKVLSQLYLESKQYKLAYDYLDSHQYYTNLIIDDTKAKANAYQMAKFKHQ
CCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHH
EQAREIALLNQERQLVETQKELDQSDRTNDVMIMSMLVGSVIFLSFFLINSHRQKIRYRK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTDRLTGAYNRGAGQDFAENEFVQVSMRQAEFSVVVFDLDLFKNINDGYGHATGDWTL
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEHHHHHCCCCCCCCCCCCHHH
KHVVSAVKPLIRDSDIFTRMGGEEFALFLPYSSEEVALGIAQRCKEAIAAIDSKYSGHSF
HHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
KVTASFGVSSNKLEDLSLDPLLKRADIALYTSKHLGRNRVTLYTPELELQCSSETQRSLV
EEEEECCCCCCCCCCCCCCHHHHHCCEEEEEHHCCCCCCEEEECCCEEEEECCCCCCCCC
FN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]