Click here to switch to the map view.

The map label for this gene is surE

Identifier: 167623161

GI number: 167623161

Start: 1491195

End: 1491947

Strand: Direct

Name: surE

Synonym: Shal_1227

Alternate gene names: 167623161

Gene position: 1491195-1491947 (Clockwise)

Preceding gene: 167623160

Following gene: 167623162

Centisome position: 28.53

GC content: 46.75

Gene sequence:

>753_bases
ATGAAGATTTTAATCAGTAATGATGATGGGGTGAACGCAGAAGGTATTGCTGCCTTAACGACCGCATTAAACCAGATAGC
AGAAACGCTCACCGTAGGGCCCGACAGAAACTGCTCTGGAGCGAGTAATTCGTTAACCTTGACCAATCCGCTACGACTGA
ATACCTTAGATAATGGTTTTATCTCGGTAAGTGGCACGCCGACTGACTGCGTGCACCTTGCAATTAGAGAGTTGTACCAA
GATGAACCCGATATGGTGGTCTCAGGTATTAATGCGGGTGCCAATATGGGTGATGATACCCTGTATTCAGGCACCGTTGC
AGCAGCAATGGAGGGGCGGTTCTTGGGCTTTCCTGCCATTGCCATCTCATTAGTTGGTCATGAGTTGAAACATTATGATA
CCGCGGCTCATTATGCATTAAAAATTGTTAAAGCCTTGCAAGATAGCCCAATTGCACAAGATAAGATCTTGAATATTAAT
GTGCCGGATCTTCCTTTGGCTGAAGTCAAAGGCATTAAGATTACCCGCCTTGGTGCAAGGCACAGAGCTGAAGGCATGGT
GAGGACCCAAGATCCTGCTGGTAGAGAGATTTTTTGGTTAGGACCTCCGGGCGACGAGCAGGATGCCAGTGATGGTACAG
ACTTTTATGCCGTAGCTAACGGTTATGTGTCTATCACGCCATTAACGGTCGATTTAACGGCATTTGAGCAACTGAGTGCC
TTAGAGTCTTGGTTAACCCAGATCCACGATTAG

Upstream 100 bases:

>100_bases
ATGCAACCTCAGTACTACGTGAGTTATTCCAGTATCAAGATGTTCAAGAGGTCGCGCGTCAACAGATGCTAGCTGATCAA
AGAAGCGCTGAGGCCGATTA

Downstream 100 bases:

>100_bases
TTCACGCACGACCCGGTTTACGAGGGTCGTGCAGAGTTAACGAATAGCTCCGTGACAGTATCACCACTATTCGAATAAAT
TAAATATTGGAAAACAGAAA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKILISNDDGVNAEGIAALTTALNQIAETLTVGPDRNCSGASNSLTLTNPLRLNTLDNGFISVSGTPTDCVHLAIRELYQ
DEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAIAISLVGHELKHYDTAAHYALKIVKALQDSPIAQDKILNIN
VPDLPLAEVKGIKITRLGARHRAEGMVRTQDPAGREIFWLGPPGDEQDASDGTDFYAVANGYVSITPLTVDLTAFEQLSA
LESWLTQIHD

Sequences:

>Translated_250_residues
MKILISNDDGVNAEGIAALTTALNQIAETLTVGPDRNCSGASNSLTLTNPLRLNTLDNGFISVSGTPTDCVHLAIRELYQ
DEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAIAISLVGHELKHYDTAAHYALKIVKALQDSPIAQDKILNIN
VPDLPLAEVKGIKITRLGARHRAEGMVRTQDPAGREIFWLGPPGDEQDASDGTDFYAVANGYVSITPLTVDLTAFEQLSA
LESWLTQIHD
>Mature_250_residues
MKILISNDDGVNAEGIAALTTALNQIAETLTVGPDRNCSGASNSLTLTNPLRLNTLDNGFISVSGTPTDCVHLAIRELYQ
DEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAIAISLVGHELKHYDTAAHYALKIVKALQDSPIAQDKILNIN
VPDLPLAEVKGIKITRLGARHRAEGMVRTQDPAGREIFWLGPPGDEQDASDGTDFYAVANGYVSITPLTVDLTAFEQLSA
LESWLTQIHD

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=249, Percent_Identity=58.2329317269076, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_SHEHH (B0TK09)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673455.1
- ProteinModelPortal:   B0TK09
- SMR:   B0TK09
- GeneID:   5903841
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1227
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   SHAL458817:SHAL_1227-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 26673; Mature: 26673

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILISNDDGVNAEGIAALTTALNQIAETLTVGPDRNCSGASNSLTLTNPLRLNTLDNGF
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEECCCCE
ISVSGTPTDCVHLAIRELYQDEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAI
EEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEHHCCCCCCCHHH
AISLVGHELKHYDTAAHYALKIVKALQDSPIAQDKILNINVPDLPLAEVKGIKITRLGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHCCEEEEECCCH
HRAEGMVRTQDPAGREIFWLGPPGDEQDASDGTDFYAVANGYVSITPLTVDLTAFEQLSA
HHHCCCEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEHHHHHHHHH
LESWLTQIHD
HHHHHHHHCC
>Mature Secondary Structure
MKILISNDDGVNAEGIAALTTALNQIAETLTVGPDRNCSGASNSLTLTNPLRLNTLDNGF
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEECCCCE
ISVSGTPTDCVHLAIRELYQDEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAI
EEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEHHCCCCCCCHHH
AISLVGHELKHYDTAAHYALKIVKALQDSPIAQDKILNINVPDLPLAEVKGIKITRLGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHCCEEEEECCCH
HRAEGMVRTQDPAGREIFWLGPPGDEQDASDGTDFYAVANGYVSITPLTVDLTAFEQLSA
HHHCCCEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEHHHHHHHHH
LESWLTQIHD
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA