Click here to switch to the map view.

The map label for this gene is yggW [H]

Identifier: 167623100

GI number: 167623100

Start: 1420455

End: 1421591

Strand: Reverse

Name: yggW [H]

Synonym: Shal_1166

Alternate gene names: 167623100

Gene position: 1421591-1420455 (Counterclockwise)

Preceding gene: 167623101

Following gene: 167623099

Centisome position: 27.2

GC content: 47.85

Gene sequence:

>1137_bases
ATGTTAACCCTGCCACCGCTAAGCCTCTATATCCATATTCCTTGGTGTGTACAGAAGTGTCCTTATTGTGACTTCAATTC
CCATGGACAACATGGCGAACTGCCCCAGACTGAATATGTCGATGCCCTGATTAAGGATCTCAAACAGGATCTGCATTATG
TGCAGGGCAGAGCTTTACACACCATTTTTATCGGTGGCGGCACCCCCTCTTTGTTTGATGCCGCGCACATTGCGCGTTTA
CTGACTGAAGTCGATACCCTTATTCCCTTTAGCGACAATATTGAAATCACCATGGAGGCCAACCCTGGTACCCTAGAACA
TGATGATTTTGAGGCCTATTGCAAGGCAGGTATTACTCGCCTTTCAATCGGAGTGCAGAGCTTCTCTACCGATAAGCTCA
ACCTGCTAGGGCGCATTCATAATCAAGATGAGGCTCAGGTGGCTGCCCAAAAAGCGAAAGTCTCGGGCTACCAGAGCTTT
AACTTAGACTTGATGCATGGTTTGCCAAACCAAAGTTTTGACGAGGCTCTGGCCGACATTGAAACGGCAGCAGAGCTTGC
GCCGCCGCACCTGTCTTGGTATCAACTAACGATTGAGCCTAATACCCTGTACCACTCTAAACCGCCACAATTGCCAGATG
ATGAAAACTTGTGGCAGATCTATGAGCAAGGACAAAAGCGTCTAGCCGAACTGGGTTATCAGCAGTATGAGATCTCGGCT
TACGCAAAAGAGGGCTATCAGTGCAGACATAACCTTAACTATTGGCAGTTTGGTGACTACCTAGGCATAGGTTGTGGTGC
CCACGGAAAAGTGACCTTACTTAATGAAAATAAGATTATTCGCACCGTCAAAATTAAGCACCCTAAAGGCTATTTAGCGG
CTGATATCTACACCTACGAAACCACCGAAGTGGCAGAGGAAGACAGGGCCCTAGAGTATCTGATGAATCGCTTACGCCTA
ATGAGTCCCATTCCAAAACTTGAGTTCGAGCAGCGCACCAGTTTGCCCCGAGACACGATTAGTGACGGCATCAAGCAAGC
CTGTGCTAAAGGCTTAATGACAGAATCAGATGAACACTGGCAGTTGACTAGCAAAGGCCACCTATTCGTCAACGAGCTGC
TGTCACAGTTCCTGTAG

Upstream 100 bases:

>100_bases
CAGCCGAGCTAAGCAGTGATGAGAAAAACAAACTCAGCCATCGCGGTAAGGCATTGGTATTGTTAATTGAAGCCATGAAG
CAACAAGGTATCTTTAACTA

Downstream 100 bases:

>100_bases
TGAACATTAAACCCTACTAATACTTATTAAGCCGTTGAATTAATGGTCATTAGGCTAACAATTTGCTTCTATAGAAATAT
TTTCTAACACTTAAAACAAA

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYVDALIKDLKQDLHYVQGRALHTIFIGGGTPSLFDAAHIARL
LTEVDTLIPFSDNIEITMEANPGTLEHDDFEAYCKAGITRLSIGVQSFSTDKLNLLGRIHNQDEAQVAAQKAKVSGYQSF
NLDLMHGLPNQSFDEALADIETAAELAPPHLSWYQLTIEPNTLYHSKPPQLPDDENLWQIYEQGQKRLAELGYQQYEISA
YAKEGYQCRHNLNYWQFGDYLGIGCGAHGKVTLLNENKIIRTVKIKHPKGYLAADIYTYETTEVAEEDRALEYLMNRLRL
MSPIPKLEFEQRTSLPRDTISDGIKQACAKGLMTESDEHWQLTSKGHLFVNELLSQFL

Sequences:

>Translated_378_residues
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYVDALIKDLKQDLHYVQGRALHTIFIGGGTPSLFDAAHIARL
LTEVDTLIPFSDNIEITMEANPGTLEHDDFEAYCKAGITRLSIGVQSFSTDKLNLLGRIHNQDEAQVAAQKAKVSGYQSF
NLDLMHGLPNQSFDEALADIETAAELAPPHLSWYQLTIEPNTLYHSKPPQLPDDENLWQIYEQGQKRLAELGYQQYEISA
YAKEGYQCRHNLNYWQFGDYLGIGCGAHGKVTLLNENKIIRTVKIKHPKGYLAADIYTYETTEVAEEDRALEYLMNRLRL
MSPIPKLEFEQRTSLPRDTISDGIKQACAKGLMTESDEHWQLTSKGHLFVNELLSQFL
>Mature_378_residues
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYVDALIKDLKQDLHYVQGRALHTIFIGGGTPSLFDAAHIARL
LTEVDTLIPFSDNIEITMEANPGTLEHDDFEAYCKAGITRLSIGVQSFSTDKLNLLGRIHNQDEAQVAAQKAKVSGYQSF
NLDLMHGLPNQSFDEALADIETAAELAPPHLSWYQLTIEPNTLYHSKPPQLPDDENLWQIYEQGQKRLAELGYQQYEISA
YAKEGYQCRHNLNYWQFGDYLGIGCGAHGKVTLLNENKIIRTVKIKHPKGYLAADIYTYETTEVAEEDRALEYLMNRLRL
MSPIPKLEFEQRTSLPRDTISDGIKQACAKGLMTESDEHWQLTSKGHLFVNELLSQFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=283, Percent_Identity=32.8621908127208, Blast_Score=165, Evalue=7e-41,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=57.4074074074074, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI87082341, Length=280, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42900; Mature: 42900

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYVDALIKDLKQDLHYVQGRALH
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
TIFIGGGTPSLFDAAHIARLLTEVDTLIPFSDNIEITMEANPGTLEHDDFEAYCKAGITR
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCEE
LSIGVQSFSTDKLNLLGRIHNQDEAQVAAQKAKVSGYQSFNLDLMHGLPNQSFDEALADI
EEECHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEHCCCCCCCCHHHHHHHH
ETAAELAPPHLSWYQLTIEPNTLYHSKPPQLPDDENLWQIYEQGQKRLAELGYQQYEISA
HHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEHHH
YAKEGYQCRHNLNYWQFGDYLGIGCGAHGKVTLLNENKIIRTVKIKHPKGYLAADIYTYE
HHHCCHHHHCCCCCEECCCEEEECCCCCCEEEEEECCCEEEEEEEECCCCCEEEEEEEEC
TTEVAEEDRALEYLMNRLRLMSPIPKLEFEQRTSLPRDTISDGIKQACAKGLMTESDEHW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCE
QLTSKGHLFVNELLSQFL
EECCCCCHHHHHHHHHHC
>Mature Secondary Structure
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYVDALIKDLKQDLHYVQGRALH
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
TIFIGGGTPSLFDAAHIARLLTEVDTLIPFSDNIEITMEANPGTLEHDDFEAYCKAGITR
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCEE
LSIGVQSFSTDKLNLLGRIHNQDEAQVAAQKAKVSGYQSFNLDLMHGLPNQSFDEALADI
EEECHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEHCCCCCCCCHHHHHHHH
ETAAELAPPHLSWYQLTIEPNTLYHSKPPQLPDDENLWQIYEQGQKRLAELGYQQYEISA
HHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEHHH
YAKEGYQCRHNLNYWQFGDYLGIGCGAHGKVTLLNENKIIRTVKIKHPKGYLAADIYTYE
HHHCCHHHHCCCCCEECCCEEEECCCCCCEEEEEECCCEEEEEEEECCCCCEEEEEEEEC
TTEVAEEDRALEYLMNRLRLMSPIPKLEFEQRTSLPRDTISDGIKQACAKGLMTESDEHW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCE
QLTSKGHLFVNELLSQFL
EECCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]