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The map label for this gene is uppP

Identifier: 167622952

GI number: 167622952

Start: 1243214

End: 1244014

Strand: Direct

Name: uppP

Synonym: Shal_1013

Alternate gene names: 167622952

Gene position: 1243214-1244014 (Clockwise)

Preceding gene: 167622951

Following gene: 167622953

Centisome position: 23.78

GC content: 44.44

Gene sequence:

>801_bases
ATGGATACCTTTCAGGTGATTATATTGGCTCTTATTCAGGGCCTCACCGAGTTTTTGCCGATCTCAAGTTCCGCTCACCT
TATTTTACCTGCTCAGCTGTTGGGCTGGGAAGATCAAGGTTTGTCGTTTGATGTGGCGGTCAATACGGGCTCGTTATTAG
CCGTAGTGATGTACTTTCGCCGCGAGCTGTTATCTATGTTTACCGCGTGGACAAGCAGTATTGTTACGGGTAAGCAAACT
CAAGAGAGTAAGTTATCTTGGTGGATTATTTTAGCGACTATTCCTGCGGTGATTGTTGGTTTTAGCGCTAAAGGTTTTAT
CGAAACGCATTTTCGCAGTATTGAAGTCATTGCAGCTACCACCATTATTTTCGGTCTACTACTGTGGTGGGCGGATAAAA
TGCAGCGTGAAGGTTTTAACGAGTTTCAAGTTGGCTGGAAAAAAGCGTTAGTGATTGGTATTGCACAGGCGATGGCGCTT
ATTCCTGGCACTTCTCGTTCTGGTGCGACGATTACAGCGGCACTGATGCTGGGGTTAAGTCGTGAGGCTGCAGCACGTTT
TTCATTTTTGATGTCGGTACCAGTGAGCTTAGGTGCCGCGATTCTGGTGACCAAAGATCTATTGGATAGCGGTCAAGTTA
TCGATTATCAAGCATTAGGTCTGGGTATTGTGGTGTCATTTATTGCGGCATACATCTGTATTCATTACTTCTTAAAGATC
ATCAGCAAGATGGGAATGACACCATTTGTGGTTTATCGCCTCGCATTAGGTGCGGTGTTATGTGGTTTTATCTTTTTATA
A

Upstream 100 bases:

>100_bases
GTATCAAACCCTTTGGGATAGCTACGACAAGAGTCAGCAATCATTATGGCCAGTTGAATTTAGCTGGTCTAAGTAAAACC
TTTTTTGATTTAGGATAGTT

Downstream 100 bases:

>100_bases
TTGTAGGGTAAGCCACCCTATAATTTATCATTCAAGCTAATTGATGAGCGTGTTATGAATAGTATTTATCTTTGTCCTGT
ATGTCAGTCACCTTTTATGG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLLAVVMYFRRELLSMFTAWTSSIVTGKQT
QESKLSWWIILATIPAVIVGFSAKGFIETHFRSIEVIAATTIIFGLLLWWADKMQREGFNEFQVGWKKALVIGIAQAMAL
IPGTSRSGATITAALMLGLSREAAARFSFLMSVPVSLGAAILVTKDLLDSGQVIDYQALGLGIVVSFIAAYICIHYFLKI
ISKMGMTPFVVYRLALGAVLCGFIFL

Sequences:

>Translated_266_residues
MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLLAVVMYFRRELLSMFTAWTSSIVTGKQT
QESKLSWWIILATIPAVIVGFSAKGFIETHFRSIEVIAATTIIFGLLLWWADKMQREGFNEFQVGWKKALVIGIAQAMAL
IPGTSRSGATITAALMLGLSREAAARFSFLMSVPVSLGAAILVTKDLLDSGQVIDYQALGLGIVVSFIAAYICIHYFLKI
ISKMGMTPFVVYRLALGAVLCGFIFL
>Mature_266_residues
MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLLAVVMYFRRELLSMFTAWTSSIVTGKQT
QESKLSWWIILATIPAVIVGFSAKGFIETHFRSIEVIAATTIIFGLLLWWADKMQREGFNEFQVGWKKALVIGIAQAMAL
IPGTSRSGATITAALMLGLSREAAARFSFLMSVPVSLGAAILVTKDLLDSGQVIDYQALGLGIVVSFIAAYICIHYFLKI
ISKMGMTPFVVYRLALGAVLCGFIFL

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=261, Percent_Identity=36.0153256704981, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SHEHH (B0TIP2)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673246.1
- GeneID:   5905818
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1013
- HOGENOM:   HBG391969
- OMA:   FKAWIAS
- ProtClustDB:   PRK00281
- BioCyc:   SHAL458817:SHAL_1013-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28994; Mature: 28994

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1fa4a8d0)-; HASH(0x1fb55d1c)-; HASH(0x1fbba424)-; HASH(0x20172800)-; HASH(0x20172b30)-; HASH(0x1f51fd30)-; HASH(0x1fa58278)-; HASH(0x204081ac)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLLAVVMYFR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEEEEECCHHHHHHHHHHH
RELLSMFTAWTSSIVTGKQTQESKLSWWIILATIPAVIVGFSAKGFIETHFRSIEVIAAT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TIIFGLLLWWADKMQREGFNEFQVGWKKALVIGIAQAMALIPGTSRSGATITAALMLGLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
REAAARFSFLMSVPVSLGAAILVTKDLLDSGQVIDYQALGLGIVVSFIAAYICIHYFLKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ISKMGMTPFVVYRLALGAVLCGFIFL
HHHCCCHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLLAVVMYFR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEEEEECCHHHHHHHHHHH
RELLSMFTAWTSSIVTGKQTQESKLSWWIILATIPAVIVGFSAKGFIETHFRSIEVIAAT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TIIFGLLLWWADKMQREGFNEFQVGWKKALVIGIAQAMALIPGTSRSGATITAALMLGLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
REAAARFSFLMSVPVSLGAAILVTKDLLDSGQVIDYQALGLGIVVSFIAAYICIHYFLKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ISKMGMTPFVVYRLALGAVLCGFIFL
HHHCCCHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA