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The map label for this gene is 167622909

Identifier: 167622909

GI number: 167622909

Start: 1191313

End: 1193136

Strand: Direct

Name: 167622909

Synonym: Shal_0969

Alternate gene names: NA

Gene position: 1191313-1193136 (Clockwise)

Preceding gene: 167622904

Following gene: 167622913

Centisome position: 22.79

GC content: 49.56

Gene sequence:

>1824_bases
ATGAGATTAACAAAAATAGCTACGGCCCTAGTCGCCTTGTCTCTAGGCGTATCAGCAGGCGCTTCGGCTAGCGAAAGGTA
TGTCATTCAGGTTGATAATGATAACAAAGGCGTGATTAAGGCGCTTGCTAAGAAGGTCGGTGGTGAGCTTAATTTGGATG
GTAATGGATTTATCGCTGCGACCTTTTCGGGTAAAGATTTAGCTCAGGTTAAAGGCCTATTGAATAACCCTCATGCAAAA
TTAGTTGAAGTGGATCAGCCTCGTTTCTTAATGTCATTTAGCGATGATGCGGGTAACCCAATGACGCAGCAAATCACCCC
TTATGCTGTTTATCAATCAAACGTTAATGATATAGGCTTCAATGCCAGCGCAGGTATGAAGGTCTGTATAATCGACTCAG
GTTTAGATAGAAGTAACGGTGATTTTGTTTGGAACAATATTAGTGGTGACAACGATGGTGGCACCGGTAATTGGGACGAA
AATGGTGGGCCACACGGTACACATGTCGCGGGTACAATTGGTGCGGCTGACAACAATATCGGCGTTGTGGGTATGGCTCC
TGGCGTCGATATGCATATCATTAAAGTATTCAATGCCGATGGTTGGGGCTACTCATCGGATCTCGCCCATGCAGCCAATC
TATGTAGTGATGCGGGGGCGAATATTATTAGTATGAGCTTAGGTGGCGGAGGCTCTAACTCTACCGAGTCTAACGCTTTC
CAGTCATTCAGTGATGCAGGTGGTCTAGTCGTGGCTGCTGCGGGTAATGATGGTAATAGCGTACGTTCATATCCAGCAGG
TTATCCGTCTGTGATGATGGTGGGGGCAAATGATGCGACGGATACGATTGCAGACTTCTCACAATACCCAGGCTGTACGA
CTGGCCGAGGCAAGAAGCAACGCACAGACACTAGTATCTGTGTCGAGATCGCCGCAGGTGGCGTAGATACCCTCTCGACT
TATCCTGCGGGTATGGCGACGGCCTCTAATATGAGTGCCGATGGTAACCCGCTAGCCAGCTCAGCGATGGAGAACTCGGG
TTCAGTCAACGGCAGTACTTATCATATGGGCACCGCTGAAGCGCAAGATTCGTCGGCCAATGGTAAGGTGTGTGTGATTG
ATCGCGGCGCAATCTCATTCCATGACAAGGTACTTAATTGTGAGAACTCGGGGGGGATCGGTGCCATTATCATCAACAAT
GAGCCAGGTATGCTGTATGGCACGCTAGGTGATACCAATGCTACGACGATCCCTGCAGCCGGTGCTACATTTGAAGACCG
AACTGCTATCATTGCAGCAAGCAGTGCGAACCTCTCAATTGGTACCTCTGATTACGGCTTTATGAGTGGTACATCAATGG
CGACTCCGGCTGTATCGGGCATTGCCGCGCGCGTTTGGTCTAACCATAACCAATGTACAGGTGAAGAGATCCGTGCGGCG
CTAAATGCGAGTGCTAGAGACTCTGGTGCTAGCGGACACGATGTCTACTTTGGGCACGGTATTGCTGATGCGGCTGCCGC
CGATACCTACCTAACGACAAACGGTTGTTCTGGTGGCGATGGTGGTGAGCCTAGTACGGGCGATGGCCTGAGCGTAACCA
CCAACCACTATAAGCAAAAAGGTGTTAAGATTGTGGAGCTTAGCTTCAGTGGCGCAGCGGGTAGTAGTATCGATGTTTAC
CGTAACGGTACGCAAATCGATAGTGCTTCTAGTGCCGCGACCTATACCGATACCATTACCAGTAAAGGTGGTGGTACCTA
TACCTACAAGGCCTGTGATAGCGGAACATCAACTTGTAGTGCCGATGTCAGCGTGACCTTCTAA

Upstream 100 bases:

>100_bases
GGTTTTTTTAACCAATAAACCACTAAAATTAAGTTTAAAAAACTAACAATAAATTGGCTTGGGTTTACGGCCTAATATCA
AGATTTTGGAGCGAATAAAT

Downstream 100 bases:

>100_bases
GAGTTAACCTCAAGTAGCAAAAGGCCTGCTGATGCAGGCCTTTTTTATGTTTAAGCTATAGTCAGTTCTAAATGTGTGTT
TGCATATTTTGATCTTGATA

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MRLTKIATALVALSLGVSAGASASERYVIQVDNDNKGVIKALAKKVGGELNLDGNGFIAATFSGKDLAQVKGLLNNPHAK
LVEVDQPRFLMSFSDDAGNPMTQQITPYAVYQSNVNDIGFNASAGMKVCIIDSGLDRSNGDFVWNNISGDNDGGTGNWDE
NGGPHGTHVAGTIGAADNNIGVVGMAPGVDMHIIKVFNADGWGYSSDLAHAANLCSDAGANIISMSLGGGGSNSTESNAF
QSFSDAGGLVVAAAGNDGNSVRSYPAGYPSVMMVGANDATDTIADFSQYPGCTTGRGKKQRTDTSICVEIAAGGVDTLST
YPAGMATASNMSADGNPLASSAMENSGSVNGSTYHMGTAEAQDSSANGKVCVIDRGAISFHDKVLNCENSGGIGAIIINN
EPGMLYGTLGDTNATTIPAAGATFEDRTAIIAASSANLSIGTSDYGFMSGTSMATPAVSGIAARVWSNHNQCTGEEIRAA
LNASARDSGASGHDVYFGHGIADAAAADTYLTTNGCSGGDGGEPSTGDGLSVTTNHYKQKGVKIVELSFSGAAGSSIDVY
RNGTQIDSASSAATYTDTITSKGGGTYTYKACDSGTSTCSADVSVTF

Sequences:

>Translated_607_residues
MRLTKIATALVALSLGVSAGASASERYVIQVDNDNKGVIKALAKKVGGELNLDGNGFIAATFSGKDLAQVKGLLNNPHAK
LVEVDQPRFLMSFSDDAGNPMTQQITPYAVYQSNVNDIGFNASAGMKVCIIDSGLDRSNGDFVWNNISGDNDGGTGNWDE
NGGPHGTHVAGTIGAADNNIGVVGMAPGVDMHIIKVFNADGWGYSSDLAHAANLCSDAGANIISMSLGGGGSNSTESNAF
QSFSDAGGLVVAAAGNDGNSVRSYPAGYPSVMMVGANDATDTIADFSQYPGCTTGRGKKQRTDTSICVEIAAGGVDTLST
YPAGMATASNMSADGNPLASSAMENSGSVNGSTYHMGTAEAQDSSANGKVCVIDRGAISFHDKVLNCENSGGIGAIIINN
EPGMLYGTLGDTNATTIPAAGATFEDRTAIIAASSANLSIGTSDYGFMSGTSMATPAVSGIAARVWSNHNQCTGEEIRAA
LNASARDSGASGHDVYFGHGIADAAAADTYLTTNGCSGGDGGEPSTGDGLSVTTNHYKQKGVKIVELSFSGAAGSSIDVY
RNGTQIDSASSAATYTDTITSKGGGTYTYKACDSGTSTCSADVSVTF
>Mature_607_residues
MRLTKIATALVALSLGVSAGASASERYVIQVDNDNKGVIKALAKKVGGELNLDGNGFIAATFSGKDLAQVKGLLNNPHAK
LVEVDQPRFLMSFSDDAGNPMTQQITPYAVYQSNVNDIGFNASAGMKVCIIDSGLDRSNGDFVWNNISGDNDGGTGNWDE
NGGPHGTHVAGTIGAADNNIGVVGMAPGVDMHIIKVFNADGWGYSSDLAHAANLCSDAGANIISMSLGGGGSNSTESNAF
QSFSDAGGLVVAAAGNDGNSVRSYPAGYPSVMMVGANDATDTIADFSQYPGCTTGRGKKQRTDTSICVEIAAGGVDTLST
YPAGMATASNMSADGNPLASSAMENSGSVNGSTYHMGTAEAQDSSANGKVCVIDRGAISFHDKVLNCENSGGIGAIIINN
EPGMLYGTLGDTNATTIPAAGATFEDRTAIIAASSANLSIGTSDYGFMSGTSMATPAVSGIAARVWSNHNQCTGEEIRAA
LNASARDSGASGHDVYFGHGIADAAAADTYLTTNGCSGGDGGEPSTGDGLSVTTNHYKQKGVKIVELSFSGAAGSSIDVY
RNGTQIDSASSAATYTDTITSKGGGTYTYKACDSGTSTCSADVSVTF

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 61435; Mature: 61435

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTKIATALVALSLGVSAGASASERYVIQVDNDNKGVIKALAKKVGGELNLDGNGFIAA
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCEEEEE
TFSGKDLAQVKGLLNNPHAKLVEVDQPRFLMSFSDDAGNPMTQQITPYAVYQSNVNDIGF
EECCCHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCHHCCCCEEEEECCCCCCCC
NASAGMKVCIIDSGLDRSNGDFVWNNISGDNDGGTGNWDENGGPHGTHVAGTIGAADNNI
CCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCE
GVVGMAPGVDMHIIKVFNADGWGYSSDLAHAANLCSDAGANIISMSLGGGGSNSTESNAF
EEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
QSFSDAGGLVVAAAGNDGNSVRSYPAGYPSVMMVGANDATDTIADFSQYPGCTTGRGKKQ
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
RTDTSICVEIAAGGVDTLSTYPAGMATASNMSADGNPLASSAMENSGSVNGSTYHMGTAE
CCCCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCC
AQDSSANGKVCVIDRGAISFHDKVLNCENSGGIGAIIINNEPGMLYGTLGDTNATTIPAA
CCCCCCCCCEEEEECCCCEECCEEEECCCCCCEEEEEEECCCCEEEEECCCCCCEEECCC
GATFEDRTAIIAASSANLSIGTSDYGFMSGTSMATPAVSGIAARVWSNHNQCTGEEIRAA
CCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
LNASARDSGASGHDVYFGHGIADAAAADTYLTTNGCSGGDGGEPSTGDGLSVTTNHYKQK
HCCCCCCCCCCCCEEEEECCCCHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHC
GVKIVELSFSGAAGSSIDVYRNGTQIDSASSAATYTDTITSKGGGTYTYKACDSGTSTCS
CCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCEE
ADVSVTF
CEEEEEC
>Mature Secondary Structure
MRLTKIATALVALSLGVSAGASASERYVIQVDNDNKGVIKALAKKVGGELNLDGNGFIAA
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCEEEEE
TFSGKDLAQVKGLLNNPHAKLVEVDQPRFLMSFSDDAGNPMTQQITPYAVYQSNVNDIGF
EECCCHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCHHCCCCEEEEECCCCCCCC
NASAGMKVCIIDSGLDRSNGDFVWNNISGDNDGGTGNWDENGGPHGTHVAGTIGAADNNI
CCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCE
GVVGMAPGVDMHIIKVFNADGWGYSSDLAHAANLCSDAGANIISMSLGGGGSNSTESNAF
EEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
QSFSDAGGLVVAAAGNDGNSVRSYPAGYPSVMMVGANDATDTIADFSQYPGCTTGRGKKQ
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
RTDTSICVEIAAGGVDTLSTYPAGMATASNMSADGNPLASSAMENSGSVNGSTYHMGTAE
CCCCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCC
AQDSSANGKVCVIDRGAISFHDKVLNCENSGGIGAIIINNEPGMLYGTLGDTNATTIPAA
CCCCCCCCCEEEEECCCCEECCEEEECCCCCCEEEEEEECCCCEEEEECCCCCCEEECCC
GATFEDRTAIIAASSANLSIGTSDYGFMSGTSMATPAVSGIAARVWSNHNQCTGEEIRAA
CCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
LNASARDSGASGHDVYFGHGIADAAAADTYLTTNGCSGGDGGEPSTGDGLSVTTNHYKQK
HCCCCCCCCCCCCEEEEECCCCHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHC
GVKIVELSFSGAAGSSIDVYRNGTQIDSASSAATYTDTITSKGGGTYTYKACDSGTSTCS
CCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCEE
ADVSVTF
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]