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The map label for this gene is ytfL [H]

Identifier: 167622901

GI number: 167622901

Start: 1182215

End: 1183537

Strand: Direct

Name: ytfL [H]

Synonym: Shal_0961

Alternate gene names: 167622901

Gene position: 1182215-1183537 (Clockwise)

Preceding gene: 167622897

Following gene: 167622903

Centisome position: 22.62

GC content: 44.22

Gene sequence:

>1323_bases
ATGAGCTTCTTTGATAATGCTGTGATTATATTGCTCCTAATTGGAGTCAGTTGTTTTTTTTCTATGTCTGAAATTGCCTT
AGCGGCGGGACGCAAAATTCGTTTGCGTCAGCTTGCGGCTGAGGGTGATATTCGAGCCAATAAAGTGCTGTTACTGCAAG
AACAGCCAGGTAACTTCTTTACCGTGGTACAGATAGGCTTAAATGCCGTCGCTATTATGGGCGGTATCGTGGGTGAGTCA
GCTTTTACTCCTCATATTCACGCATTTTTGTCGTCTTGGTTGACCGGCCCCTGGCTAGACAAAATGAGCTTCCTGTTGTC
ATTTGTGATTGTGACCAGCTTATTTATCTTGATTGCCGACCTAATTCCTAAGCGTTTAGCGATGGCCTTTCCTGAAAAGG
TGGCGATGACCTTTGTTGGCCCTATGATGGTCTGCATCGTGGTGCTTAAACCGCTGGTATGGTTCTTTAATGGTTCGGCT
AACTTCGTTTTTCGTGTGTTTCAAGTGCAAACCGCGCGTAACGATGCGGTGACCTCCGATGATATCTATGCCGTTATGGA
TGCGGGCGCAGAAGCGGGAGTATTAGATAAAGGCGATCAGCTGATGATGGAAAAAGTGTTTGAGATGCAAACCATTCCTG
TCACTGCAGCGATGACCGCACGTGAGAGTTTGGCTTACTTCTTACTGCAAGATAGTGAAGATGAAATTAGAACTAAGATC
GCAGAACAGCCTCACTCAAACTTTCTTGTCTGTGATGAGCAGTTAGACACAGTCGTGGGTATCGTTAATGCAAAAAAATT
ACTGATTTGCTTAATTAACGGTGAAAGCATAAGTCTTACCGATAAAAAATTGGTGACCAACTGTTTTATCATTCCTGACA
CATTAAGCCTGTCTGAATCGATGGATTACTTTAAGAATAGTCGAGCAGATTTCGCAATAGTGATGAATGAATACTCTTTA
GTTGTGGGGGTGGTGACGGCCAAAGATCTGCAAGATGCGGTGATGGGCGCTTGGTCATTACCTGAGTGTGAAGAGCAGAT
TATTGCCCGTGACGAGCATTCATGGTTGATGGATGGCGTAACACCGATTACCGATGTGATGCGAGCCTTAGATATTGAAG
AGTTCCCACAAAACCATAACTATGAAACCATTGCTGGCTTTATGATGTTTATGCTGCGCAAAATTCCAAAGTGTACCGAC
TCCGTTAACCATGCTGGTTTTAAGTTTGAGGTCGTTGATGTGGATAGCTACAAAGTGGATCAGTTACTCGTGACCCGCAT
CGATGAGTCGAGTAAGGGTGAAGAGTTAGACCTTAAAGCCTAA

Upstream 100 bases:

>100_bases
TATACAAAGATTTACTTGGAGAAAGGTGAACACCACCAAGTAGAAATAATGATACGCAGTAAAGGGATAAGTCTGTTTTA
AGTTTTTAGAAAGGTGCTAA

Downstream 100 bases:

>100_bases
GGATAATCCGCTGTAGCGATAGTCTTAAACCTAGGTGAGTCAGTCTTGACTCACCTCTATTTTATTCCCGATCATATATC
CACCTACTCCTGACTTGCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDIRANKVLLLQEQPGNFFTVVQIGLNAVAIMGGIVGES
AFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIADLIPKRLAMAFPEKVAMTFVGPMMVCIVVLKPLVWFFNGSA
NFVFRVFQVQTARNDAVTSDDIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLAYFLLQDSEDEIRTKI
AEQPHSNFLVCDEQLDTVVGIVNAKKLLICLINGESISLTDKKLVTNCFIIPDTLSLSESMDYFKNSRADFAIVMNEYSL
VVGVVTAKDLQDAVMGAWSLPECEEQIIARDEHSWLMDGVTPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTD
SVNHAGFKFEVVDVDSYKVDQLLVTRIDESSKGEELDLKA

Sequences:

>Translated_440_residues
MSFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDIRANKVLLLQEQPGNFFTVVQIGLNAVAIMGGIVGES
AFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIADLIPKRLAMAFPEKVAMTFVGPMMVCIVVLKPLVWFFNGSA
NFVFRVFQVQTARNDAVTSDDIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLAYFLLQDSEDEIRTKI
AEQPHSNFLVCDEQLDTVVGIVNAKKLLICLINGESISLTDKKLVTNCFIIPDTLSLSESMDYFKNSRADFAIVMNEYSL
VVGVVTAKDLQDAVMGAWSLPECEEQIIARDEHSWLMDGVTPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTD
SVNHAGFKFEVVDVDSYKVDQLLVTRIDESSKGEELDLKA
>Mature_439_residues
SFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDIRANKVLLLQEQPGNFFTVVQIGLNAVAIMGGIVGESA
FTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIADLIPKRLAMAFPEKVAMTFVGPMMVCIVVLKPLVWFFNGSAN
FVFRVFQVQTARNDAVTSDDIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLAYFLLQDSEDEIRTKIA
EQPHSNFLVCDEQLDTVVGIVNAKKLLICLINGESISLTDKKLVTNCFIIPDTLSLSESMDYFKNSRADFAIVMNEYSLV
VGVVTAKDLQDAVMGAWSLPECEEQIIARDEHSWLMDGVTPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTDS
VNHAGFKFEVVDVDSYKVDQLLVTRIDESSKGEELDLKA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=389, Percent_Identity=23.1362467866324, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1790664, Length=428, Percent_Identity=55.1401869158878, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI87082033, Length=266, Percent_Identity=27.0676691729323, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693175, Length=422, Percent_Identity=21.0900473933649, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788119, Length=271, Percent_Identity=26.5682656826568, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786879, Length=274, Percent_Identity=23.3576642335766, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48929; Mature: 48797

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDIRANKVLLLQEQPGNFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEEEECCCCEE
TVVQIGLNAVAIMGGIVGESAFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIAD
EEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIPKRLAMAFPEKVAMTFVGPMMVCIVVLKPLVWFFNGSANFVFRVFQVQTARNDAVTSD
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCC
DIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLAYFLLQDSEDEIRTKI
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCHHHHHHHH
AEQPHSNFLVCDEQLDTVVGIVNAKKLLICLINGESISLTDKKLVTNCFIIPDTLSLSES
HCCCCCCEEEECHHHHHHHHHHCCCEEEEEEECCCEEEECHHHHHHEEEEECCCCCHHHH
MDYFKNSRADFAIVMNEYSLVVGVVTAKDLQDAVMGAWSLPECEEQIIARDEHSWLMDGV
HHHHHCCCCCEEEEEECCEEEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCC
TPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTDSVNHAGFKFEVVDVDSYKVD
CHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCCCCHH
QLLVTRIDESSKGEELDLKA
HHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDIRANKVLLLQEQPGNFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEEEECCCCEE
TVVQIGLNAVAIMGGIVGESAFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIAD
EEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIPKRLAMAFPEKVAMTFVGPMMVCIVVLKPLVWFFNGSANFVFRVFQVQTARNDAVTSD
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCC
DIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLAYFLLQDSEDEIRTKI
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCHHHHHHHH
AEQPHSNFLVCDEQLDTVVGIVNAKKLLICLINGESISLTDKKLVTNCFIIPDTLSLSES
HCCCCCCEEEECHHHHHHHHHHCCCEEEEEEECCCEEEECHHHHHHEEEEECCCCCHHHH
MDYFKNSRADFAIVMNEYSLVVGVVTAKDLQDAVMGAWSLPECEEQIIARDEHSWLMDGV
HHHHHCCCCCEEEEEECCEEEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCC
TPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTDSVNHAGFKFEVVDVDSYKVD
CHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCCCCHH
QLLVTRIDESSKGEELDLKA
HHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]