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The map label for this gene is surA [H]

Identifier: 167622857

GI number: 167622857

Start: 1135746

End: 1137050

Strand: Reverse

Name: surA [H]

Synonym: Shal_0917

Alternate gene names: 167622857

Gene position: 1137050-1135746 (Counterclockwise)

Preceding gene: 167622858

Following gene: 167622856

Centisome position: 21.75

GC content: 44.44

Gene sequence:

>1305_bases
ATGAAACGCTGTAACCAATTGATTTTTGCTCTTATAACATTGGCAATGAGCCAGACAATTCACGCTGCGCCAGAACCTCT
CGACCGTGTCACAGTGCAAATAAATGAAGGGATCATTTTAGAAAGTGAAGTGACGGGTATGGTAAAGACCATCAGGGCAA
ATGCTGCCAATGCGGGTCAAAAATTACCATCTGATACAGCACTGCGCACTCAGGTTATTGAGCGTTTAATCCTAACCCGT
CTTCAGTTACAGATGGCTGATAGAATTGGCCTGCACATTGGTGACTTACAGTTAGATCAAACGATTGAAAATATAGCAAA
AGAACAGAAAATGACGGTTGCGCAAATGAAGGCGCAAATCGAAAGTGAAGGGACCACATTTGCTCAATACCGTGAGCAAC
TGCGTGAAGAGATCACCTTAGGCGAAATTCAACGTATTCAGGTCCAACGCCGTATTCAGGTCTCTCCGCAGGAGATCAAT
AGCCTTGTAAAACTCATCAACGAGCAAGGTCTTAAAGAAGTTGAGTTCCAAATTGGCCATATCCTTATTGATGTGCCGAG
CGACGCTAACAGTCAGCAGCTAGAAGCAGCGAGTAAACGCGCCGCAGTCGTCATGAAACGACTAAAAGATGGTGATGACT
TTAGAAGTATCGCTATTGCCGCCTCTTCAGGCCCTAAAGCATTAGAAGGTGGTATTTGGGACTACATGAACATCAACGAG
ATGCCAACTTTATTTGCTGAAGTGGTCACTGATGCAAAGACGGGTGATATCATAGGCCCAATTAAGAGCGCATCAGGCTT
TCATATCATCAAGGTTATGGATGCTCGCGGTCTAGAAACCAAAGAAGTGAAAGAAGTTAAGTCTCGCCATATTCTACTTA
AGCCATCTCCAATTCTTTCGGAAGAACGCGCTAAGAGCATGATGGATAGATTCCTAACTCAAGTTAAATCGGGTGAGGCC
AAGTTTGAAGACTTAGCACGCCAGTACTCTGAAGATCCAGGTTCAGCTGCAAAAGGCGGTGAATTGGGGTGGGCCGATCC
AAACATCTATGTTCCAGCATTCGCCCAAGAGTTAAACAGTCTTGAAATTGGTGGCTACAGTGAACCGTTCCGTTCAACTC
ACGGCTGGCATATTGTTCAACTAGAAGAAAGACGCACAACAGACGCAACCGATAAATTTAATACGAATCGCGCTCACCAG
CTGATCTATCGTCGTAAATTTAATGAAGAGTTACAAAACTGGCTAGATGAGATGCGCGCTGAAGCATTTATCGATATTTT
TGAGCCAGAAACGAACCGAGGTTAA

Upstream 100 bases:

>100_bases
ACCTAGCTGACGACATGCAGTCAAAGCAGAACTAAAGAATCATTAACCCGGTGAGTATTTGCCGTAAATGACACTCAATA
AATGCCAAGGATTTTAGTGG

Downstream 100 bases:

>100_bases
TACTATTGTCAACTAAACGAATTGCCATCACGCCGGGTGAACCGGCGGGGATAGGCCCCGATTTAGTGATACAACTAGCT
CAGCAGGCTTGGCCTGCTGA

Product: SurA domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKRCNQLIFALITLAMSQTIHAAPEPLDRVTVQINEGIILESEVTGMVKTIRANAANAGQKLPSDTALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQTIENIAKEQKMTVAQMKAQIESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
SLVKLINEQGLKEVEFQIGHILIDVPSDANSQQLEAASKRAAVVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
MPTLFAEVVTDAKTGDIIGPIKSASGFHIIKVMDARGLETKEVKEVKSRHILLKPSPILSEERAKSMMDRFLTQVKSGEA
KFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFAQELNSLEIGGYSEPFRSTHGWHIVQLEERRTTDATDKFNTNRAHQ
LIYRRKFNEELQNWLDEMRAEAFIDIFEPETNRG

Sequences:

>Translated_434_residues
MKRCNQLIFALITLAMSQTIHAAPEPLDRVTVQINEGIILESEVTGMVKTIRANAANAGQKLPSDTALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQTIENIAKEQKMTVAQMKAQIESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
SLVKLINEQGLKEVEFQIGHILIDVPSDANSQQLEAASKRAAVVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
MPTLFAEVVTDAKTGDIIGPIKSASGFHIIKVMDARGLETKEVKEVKSRHILLKPSPILSEERAKSMMDRFLTQVKSGEA
KFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFAQELNSLEIGGYSEPFRSTHGWHIVQLEERRTTDATDKFNTNRAHQ
LIYRRKFNEELQNWLDEMRAEAFIDIFEPETNRG
>Mature_434_residues
MKRCNQLIFALITLAMSQTIHAAPEPLDRVTVQINEGIILESEVTGMVKTIRANAANAGQKLPSDTALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQTIENIAKEQKMTVAQMKAQIESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
SLVKLINEQGLKEVEFQIGHILIDVPSDANSQQLEAASKRAAVVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
MPTLFAEVVTDAKTGDIIGPIKSASGFHIIKVMDARGLETKEVKEVKSRHILLKPSPILSEERAKSMMDRFLTQVKSGEA
KFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFAQELNSLEIGGYSEPFRSTHGWHIVQLEERRTTDATDKFNTNRAHQ
LIYRRKFNEELQNWLDEMRAEAFIDIFEPETNRG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=429, Percent_Identity=41.4918414918415, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48791; Mature: 48791

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCNQLIFALITLAMSQTIHAAPEPLDRVTVQINEGIILESEVTGMVKTIRANAANAGQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCEEEEHHHHHHHHHHHHCCCCCCC
KLPSDTALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQTIENIAKEQKMTVAQMKAQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEINSLVKLINEQGLKEVEFQIGH
HCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEECE
ILIDVPSDANSQQLEAASKRAAVVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCH
MPTLFAEVVTDAKTGDIIGPIKSASGFHIIKVMDARGLETKEVKEVKSRHILLKPSPILS
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEECCCCCCC
EERAKSMMDRFLTQVKSGEAKFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFAQELNS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCHHHHHCCC
LEIGGYSEPFRSTHGWHIVQLEERRTTDATDKFNTNRAHQLIYRRKFNEELQNWLDEMRA
EECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EAFIDIFEPETNRG
HHHHEEECCCCCCC
>Mature Secondary Structure
MKRCNQLIFALITLAMSQTIHAAPEPLDRVTVQINEGIILESEVTGMVKTIRANAANAGQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCEEEEHHHHHHHHHHHHCCCCCCC
KLPSDTALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQTIENIAKEQKMTVAQMKAQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ESEGTTFAQYREQLREEITLGEIQRIQVQRRIQVSPQEINSLVKLINEQGLKEVEFQIGH
HCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEECE
ILIDVPSDANSQQLEAASKRAAVVMKRLKDGDDFRSIAIAASSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCH
MPTLFAEVVTDAKTGDIIGPIKSASGFHIIKVMDARGLETKEVKEVKSRHILLKPSPILS
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEECCCCCCC
EERAKSMMDRFLTQVKSGEAKFEDLARQYSEDPGSAAKGGELGWADPNIYVPAFAQELNS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCHHHHHCCC
LEIGGYSEPFRSTHGWHIVQLEERRTTDATDKFNTNRAHQLIYRRKFNEELQNWLDEMRA
EECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EAFIDIFEPETNRG
HHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]