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The map label for this gene is gltT [H]

Identifier: 167622767

GI number: 167622767

Start: 1030351

End: 1031649

Strand: Direct

Name: gltT [H]

Synonym: Shal_0827

Alternate gene names: 167622767

Gene position: 1030351-1031649 (Clockwise)

Preceding gene: 167622766

Following gene: 167622769

Centisome position: 19.71

GC content: 45.88

Gene sequence:

>1299_bases
ATGTCAATTCAACAACCTTCACTGGTGAAAAAAGTGTGGTCGAGCTGGATGTCTGTGCCCCTATGGCTACAGATAATGAT
TGGTATGCTATTAGGTATTTTAACTGGCATAGGCTTAGGTGAGCAGGCGACCTACTTGAAACCAATTGGAACGCTATTTG
TTAACACGATCAAGATGTTGATTGTGCCACTCGTGTTCTGTTCTTTAATTGTCGGTGTGACCTCTATGCAAGATACTGCA
AAGATGGGCCGCATTGGTTTCAAGTCGTTCGCTTTCTACTTAGGCACAACCTCTATCGCCATTACGCTAGGTTTAGCGGT
TGGCCAATTTATGCAGCCTGGTGCTGGTTTAGATATGGTGCCTCATGAAACAGCTGAAGTAATTAAGCAAGCGCCATCTG
TGATGCAAACCTTGATTGATATCGTGCCTACTAATCCGATTGCTGCACTTGCTAGTGGTCAGATTTTACAAGTTATTGTA
TTTGCGGTAGCCCTAGGTATTGCCTTGGTGTTGATTGGCGAGCATGGCAAACCAGCAATTAAGGTGTTCGAAAGTCTAGC
CGAAGCCATGTATAAGCTTACAGACTTAGTGATGAAGCTTGCACCATACGGCGTATTTGGTTTGATGGCTTGGGTTGCGG
GCGAATACGGCGTGGATATGTTGATGCCGTTAATCAAGGTGATTGTGGCAGTATATATCGGTTGCTTCTTGCATGTTGTT
GGCTTCTACAGTTTTGTTTTAGTGGTGTTTGCTAAGCTTAATCCAATTCAATTTTTCAAAGGTATTAGCAATGCGATTGC
TGTCGCTTATACCACCTCTAGTTCTGCAGGCACGCTGCCAGCCAGTATGAAATGTGCCAGCGAATACTTAGGCGTTAACA
AGAAGATCTCAAGTTTTGTACTGCCTCTAGGTACCACGATTAACATGGACGGCACCGCGCTTTACCAAGGCGTTACGGCA
CTGTTTGTGGCGCAAGCTTTTGGTATCGATCTGACTTGGGTCGATTACATCACTATCATCTTAACTGCAACGTTAGCCTC
AATTGGTACCGCTGGTGTGCCAGGAGCGGGCCTTGTAATGCTAACCTTGGTATTGACCACAGTGGGTCTACCGCTTGAAG
GTGTTGCCCTGATTGCCGGTATCGACCGTATCTTGGATATGGCGCGCACGGTTGTGAACGTGTCTGGTGACTTAGTCGCG
ACCACTGTGATTGCAAAATCTGAAGGCGAAATCGACGTTGAGCATTACAACGCCAATGCCGAAGAAAGTGCAGAGATGGC
TGAAAGGTTAAAGTCTTAA

Upstream 100 bases:

>100_bases
AGATCATCTCTCGCTTCTAAAGCTTATGCTAAACTGCCGCGTTATTTTTGAGCTAGTCATGCGCTGGTAGTCCCCCCTTC
AATTGTTTCAAGGTTTAAAT

Downstream 100 bases:

>100_bases
TTGCTTAATTAATTATTCACCATTGTGTTAACGCATAAAAAAACCGCCAAAAGGCGGTTTTTTTATGTCTGGAACATTTA
TGACGATTTACCATGGATGG

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSIQQPSLVKKVWSSWMSVPLWLQIMIGMLLGILTGIGLGEQATYLKPIGTLFVNTIKMLIVPLVFCSLIVGVTSMQDTA
KMGRIGFKSFAFYLGTTSIAITLGLAVGQFMQPGAGLDMVPHETAEVIKQAPSVMQTLIDIVPTNPIAALASGQILQVIV
FAVALGIALVLIGEHGKPAIKVFESLAEAMYKLTDLVMKLAPYGVFGLMAWVAGEYGVDMLMPLIKVIVAVYIGCFLHVV
GFYSFVLVVFAKLNPIQFFKGISNAIAVAYTTSSSAGTLPASMKCASEYLGVNKKISSFVLPLGTTINMDGTALYQGVTA
LFVAQAFGIDLTWVDYITIILTATLASIGTAGVPGAGLVMLTLVLTTVGLPLEGVALIAGIDRILDMARTVVNVSGDLVA
TTVIAKSEGEIDVEHYNANAEESAEMAERLKS

Sequences:

>Translated_432_residues
MSIQQPSLVKKVWSSWMSVPLWLQIMIGMLLGILTGIGLGEQATYLKPIGTLFVNTIKMLIVPLVFCSLIVGVTSMQDTA
KMGRIGFKSFAFYLGTTSIAITLGLAVGQFMQPGAGLDMVPHETAEVIKQAPSVMQTLIDIVPTNPIAALASGQILQVIV
FAVALGIALVLIGEHGKPAIKVFESLAEAMYKLTDLVMKLAPYGVFGLMAWVAGEYGVDMLMPLIKVIVAVYIGCFLHVV
GFYSFVLVVFAKLNPIQFFKGISNAIAVAYTTSSSAGTLPASMKCASEYLGVNKKISSFVLPLGTTINMDGTALYQGVTA
LFVAQAFGIDLTWVDYITIILTATLASIGTAGVPGAGLVMLTLVLTTVGLPLEGVALIAGIDRILDMARTVVNVSGDLVA
TTVIAKSEGEIDVEHYNANAEESAEMAERLKS
>Mature_431_residues
SIQQPSLVKKVWSSWMSVPLWLQIMIGMLLGILTGIGLGEQATYLKPIGTLFVNTIKMLIVPLVFCSLIVGVTSMQDTAK
MGRIGFKSFAFYLGTTSIAITLGLAVGQFMQPGAGLDMVPHETAEVIKQAPSVMQTLIDIVPTNPIAALASGQILQVIVF
AVALGIALVLIGEHGKPAIKVFESLAEAMYKLTDLVMKLAPYGVFGLMAWVAGEYGVDMLMPLIKVIVAVYIGCFLHVVG
FYSFVLVVFAKLNPIQFFKGISNAIAVAYTTSSSAGTLPASMKCASEYLGVNKKISSFVLPLGTTINMDGTALYQGVTAL
FVAQAFGIDLTWVDYITIILTATLASIGTAGVPGAGLVMLTLVLTTVGLPLEGVALIAGIDRILDMARTVVNVSGDLVAT
TVIAKSEGEIDVEHYNANAEESAEMAERLKS

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI40254478, Length=476, Percent_Identity=32.3529411764706, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI21314632, Length=436, Percent_Identity=31.8807339449541, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI169790839, Length=444, Percent_Identity=30.8558558558559, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI66773030, Length=459, Percent_Identity=32.244008714597, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI5032093, Length=375, Percent_Identity=36.2666666666667, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI4827012, Length=302, Percent_Identity=36.4238410596026, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI223468564, Length=250, Percent_Identity=40.4, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI223468566, Length=250, Percent_Identity=40.4, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI194239697, Length=255, Percent_Identity=39.2156862745098, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI301601644, Length=197, Percent_Identity=36.0406091370558, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI262359914, Length=378, Percent_Identity=27.5132275132275, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1790514, Length=421, Percent_Identity=38.479809976247, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1789947, Length=408, Percent_Identity=36.2745098039216, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1788024, Length=412, Percent_Identity=28.8834951456311, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789473, Length=376, Percent_Identity=27.1276595744681, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71996953, Length=464, Percent_Identity=35.1293103448276, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71983099, Length=473, Percent_Identity=33.1923890063425, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71983106, Length=468, Percent_Identity=33.3333333333333, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17537407, Length=462, Percent_Identity=31.3852813852814, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI193206505, Length=467, Percent_Identity=31.9057815845824, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI193206654, Length=431, Percent_Identity=30.1624129930394, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17541374, Length=394, Percent_Identity=29.9492385786802, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24583025, Length=441, Percent_Identity=30.8390022675737, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17137668, Length=441, Percent_Identity=30.8390022675737, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24583023, Length=441, Percent_Identity=30.8390022675737, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281360481, Length=461, Percent_Identity=29.2841648590022, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI281360483, Length=461, Percent_Identity=29.2841648590022, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI17137666, Length=461, Percent_Identity=29.2841648590022, Blast_Score=145, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45740; Mature: 45609

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCC
>Mature Secondary Structure 
SIQQPSLVKKVWSSWMSVPLWLQIMIGMLLGILTGIGLGEQATYLKPIGTLFVNTIKML
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IVPLVFCSLIVGVTSMQDTAKMGRIGFKSFAFYLGTTSIAITLGLAVGQFMQPGAGLDMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PHETAEVIKQAPSVMQTLIDIVPTNPIAALASGQILQVIVFAVALGIALVLIGEHGKPAI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
KVFESLAEAMYKLTDLVMKLAPYGVFGLMAWVAGEYGVDMLMPLIKVIVAVYIGCFLHVV
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GFYSFVLVVFAKLNPIQFFKGISNAIAVAYTTSSSAGTLPASMKCASEYLGVNKKISSFV
HHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHH
LPLGTTINMDGTALYQGVTALFVAQAFGIDLTWVDYITIILTATLASIGTAGVPGAGLVM
HCCCCEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LTLVLTTVGLPLEGVALIAGIDRILDMARTVVNVSGDLVATTVIAKSEGEIDVEHYNANA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCEEEEECCCCH
EESAEMAERLKS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]