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The map label for this gene is aroQ

Identifier: 167622536

GI number: 167622536

Start: 720753

End: 721208

Strand: Reverse

Name: aroQ

Synonym: Shal_0596

Alternate gene names: 167622536

Gene position: 721208-720753 (Counterclockwise)

Preceding gene: 167622537

Following gene: 167622535

Centisome position: 13.8

GC content: 46.93

Gene sequence:

>456_bases
ATGAGCAGCCAACCCAAGATCCTATTAGTTAATGGTCCTAACTTAAACTTACTCGGACGTCGTGAACCTGGGCATTACGG
CCATCATACTCTTGAGCAGATTGTCGATGACCTTAAGCAAAGTGCGACTCAGGCTGGTATACAGTTAGATCATATTCAAT
CTAACGCCGAGCATCTGCTTATTGAAGCCATTCACAACAGTGACGCCGATATGGTGATTATCAATCCGGCAGCCTTTACC
CATACCAGTGTCGCCCTTAGAGATGCATTACTTGGCGTTGCGATTCCATTCATTGAAGTGCACCTTTCCAACGTGCACAG
CCGCGAGCCTTTCCGTCATCACTCCTACTTTTCCGATAAAGCTATTGGGGTGATCTGCGGTTTAGGTGCTCAAGGTTATC
AGTTCGCACTACAAGCAGCGATTGCTCGCATTCACGCTGCAGAAAAACAAGGTTAA

Upstream 100 bases:

>100_bases
CTCTACAATGTTCGACAAGCAGCTGATTTTTTGTTGAAATCAACGCTATAAGCGCATACACACTCAGCGCACATTTACCG
CGTATTGCAAGGGAATATTC

Downstream 100 bases:

>100_bases
CTACAATCCATGGATATTCGTAAGATCAAGAAGCTTATCGAGCTAGTGCAAGAATCTGATATTGCAGAACTTGAAATTAA
AGAGGGTGAAGAGTCGGTGC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MSSQPKILLVNGPNLNLLGRREPGHYGHHTLEQIVDDLKQSATQAGIQLDHIQSNAEHLLIEAIHNSDADMVIINPAAFT
HTSVALRDALLGVAIPFIEVHLSNVHSREPFRHHSYFSDKAIGVICGLGAQGYQFALQAAIARIHAAEKQG

Sequences:

>Translated_151_residues
MSSQPKILLVNGPNLNLLGRREPGHYGHHTLEQIVDDLKQSATQAGIQLDHIQSNAEHLLIEAIHNSDADMVIINPAAFT
HTSVALRDALLGVAIPFIEVHLSNVHSREPFRHHSYFSDKAIGVICGLGAQGYQFALQAAIARIHAAEKQG
>Mature_150_residues
SSQPKILLVNGPNLNLLGRREPGHYGHHTLEQIVDDLKQSATQAGIQLDHIQSNAEHLLIEAIHNSDADMVIINPAAFTH
TSVALRDALLGVAIPFIEVHLSNVHSREPFRHHSYFSDKAIGVICGLGAQGYQFALQAAIARIHAAEKQG

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_SHEHH (B0TS36)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001672830.1
- ProteinModelPortal:   B0TS36
- SMR:   B0TS36
- GeneID:   5905984
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0596
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   SHAL458817:SHAL_0596-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16447; Mature: 16316

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 26-26 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQPKILLVNGPNLNLLGRREPGHYGHHTLEQIVDDLKQSATQAGIQLDHIQSNAEHLL
CCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEHHHCCHHHEE
IEAIHNSDADMVIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHSREPFRHHSYFSDK
EEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AIGVICGLGAQGYQFALQAAIARIHAAEKQG
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSQPKILLVNGPNLNLLGRREPGHYGHHTLEQIVDDLKQSATQAGIQLDHIQSNAEHLL
CCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEHHHCCHHHEE
IEAIHNSDADMVIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHSREPFRHHSYFSDK
EEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AIGVICGLGAQGYQFALQAAIARIHAAEKQG
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA