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The map label for this gene is ubiA

Identifier: 167622484

GI number: 167622484

Start: 655192

End: 656055

Strand: Direct

Name: ubiA

Synonym: Shal_0544

Alternate gene names: 167622484

Gene position: 655192-656055 (Clockwise)

Preceding gene: 167622483

Following gene: 167622487

Centisome position: 12.53

GC content: 47.45

Gene sequence:

>864_bases
ATGAGTTTTAGGGATAAACTTGACGTTTATATGCGACTCGCGCGTATGGACCGTCCCATTGGTACCTTGTTGTTGTTGTG
GCCCTGTTTGATGGCCTTAACTTTTGCCGCAGGTGGTCTGCCAGATCTCAAAGTGTTTATCATTTTTGTTATTGGTGTGG
TGGTGATGCGAGCTTGCGGCTGCATCATCAACGACTATGCCGATAGGGATCTCGACTCCCATGTTGAACGCACCAAAGCG
AGACCCCTTGCTAGTGGCGAGATCTCCAGTAAAGAAGCACTACTGCTGTTTGGGGTGATGGGTCTATTTGCCTTTAGCTT
AGTGCTAATGCTCAACCCTCTGGTCGTACAGCTCTCCGTCGTCGGTATTATTCTTACCATTATTTACCCCTTTACCAAAC
GCTACACCAATATGCCGCAGATGTTTCTTGGCACGGTGTGGAGCTGGTCTATTCCCATGGCCTATGCGGCGCAAACTGGT
ACAGTGCCGATTGAGGCTTGGTGGCTATTTGCGGCTAACTGGTGTTGGACTGTAGCCTACGACACCATGTATGCCATGGT
GGATCGTGACGATGATCTAAAAGTCGGCATCAAGTCGACGGCAATTCTTTTTGGTCGCTATGACAGACAGATAATCGCTG
CCTTTCAGCTTGCGGCATTAAGCTGTTTTATTATTGCGGGCATGTTGGCTGGGCGAGGTGAAATTTATGGCCTAGGAATA
TTGGCCTTTATCGGCTTTGCTGTGTATCAACAGAAGTTGATTTACGGACGTGAACGCGGCCCCTGCTTTACCGCTTTTCT
CAATAATAATTGGGCAGGCATGGTGTTATATATTGCACTGACCTTAGATTATTTAATCTTATAG

Upstream 100 bases:

>100_bases
CGCTACAAATTATTCTCAATACTGGTTGAATACTGTTACAGCTCAGTCATAATGCGGGTAGAAGATTAAAGGCCGAAGAC
GTTGTAGGAGAGCCTAATAA

Downstream 100 bases:

>100_bases
TCTTACTTTAGATTAACTCAGTTATTATCTAAAACAGCCTGCATCTTAAAGACTGAGCGGCGGGCAGTTTAATTCGTACT
AATCGAGACTGCTGTTGATA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MSFRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVVVMRACGCIINDYADRDLDSHVERTKA
RPLASGEISSKEALLLFGVMGLFAFSLVLMLNPLVVQLSVVGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTG
TVPIEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIAAFQLAALSCFIIAGMLAGRGEIYGLGI
LAFIGFAVYQQKLIYGRERGPCFTAFLNNNWAGMVLYIALTLDYLIL

Sequences:

>Translated_287_residues
MSFRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVVVMRACGCIINDYADRDLDSHVERTKA
RPLASGEISSKEALLLFGVMGLFAFSLVLMLNPLVVQLSVVGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTG
TVPIEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIAAFQLAALSCFIIAGMLAGRGEIYGLGI
LAFIGFAVYQQKLIYGRERGPCFTAFLNNNWAGMVLYIALTLDYLIL
>Mature_286_residues
SFRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVVVMRACGCIINDYADRDLDSHVERTKAR
PLASGEISSKEALLLFGVMGLFAFSLVLMLNPLVVQLSVVGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTGT
VPIEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIAAFQLAALSCFIIAGMLAGRGEIYGLGIL
AFIGFAVYQQKLIYGRERGPCFTAFLNNNWAGMVLYIALTLDYLIL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=282, Percent_Identity=32.6241134751773, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=53.3807829181495, Blast_Score=291, Evalue=2e-80,
Organism=Escherichia coli, GI1786631, Length=159, Percent_Identity=30.188679245283, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=284, Percent_Identity=33.0985915492958, Blast_Score=167, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI32565247, Length=290, Percent_Identity=32.4137931034483, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=189, Percent_Identity=38.0952380952381, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI32565245, Length=145, Percent_Identity=40.6896551724138, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=40.7142857142857, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=290, Percent_Identity=31.3793103448276, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI21355567, Length=283, Percent_Identity=36.3957597173145, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_SHEHH (B0TRE7)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001672778.1
- GeneID:   5904034
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0544
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- BioCyc:   SHAL458817:SHAL_0544-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 32133; Mature: 32001

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x250421cc)-; HASH(0x260a1924)-; HASH(0x2691e28c)-; HASH(0x25e8fd64)-; HASH(0x25ebd078)-; HASH(0x267d4918)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SFRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVVVMRACG
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CIINDYADRDLDSHVERTKARPLASGEISSKEALLLFGVMGLFAFSLVLMLNPLVVQLSV
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTGTVPIEAWWLFAANWCWTVAY
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIAAFQLAALSCFIIAGMLAGRGEIYGLGI
HHHHHHHCCCCCCEECHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
LAFIGFAVYQQKLIYGRERGPCFTAFLNNNWAGMVLYIALTLDYLIL
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA