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The map label for this gene is dmsB [H]

Identifier: 167622346

GI number: 167622346

Start: 476065

End: 476688

Strand: Reverse

Name: dmsB [H]

Synonym: Shal_0406

Alternate gene names: 167622346

Gene position: 476688-476065 (Counterclockwise)

Preceding gene: 167622347

Following gene: 167622345

Centisome position: 9.12

GC content: 45.99

Gene sequence:

>624_bases
ATGAAACTAGAATACGGATTTTATGTCGATAGCAGTAAGTGTACCGGCTGCAAAACTTGTCAGGTTGCCTGCAAAGATAA
AAATGAGTTACCGATTGGTGTTAACTATCGCCGCGTATATGAATACGCAGGTGGGGAGTGGCTCAAGGGTCTTGATGACA
CATGGCAACAAAATGTATTTGCCTACTACCTATCAATCAGCTGTAACCACTGTGCAGAGCCTGCCTGCACCAAAGCTTGC
CCCACTGGTGCCATGCATAAACGGTCACAAGATGGCTTAGTTGTTGTCGATACCGATGTCTGTATTGGTTGCCGCTATTG
CGAGATGGCCTGCCCCTATGGCGCGCCACAATACAATCCAGAAAAAAAACATATGACTAAGTGCGATGGCTGCTATGAGT
TGTTAGCCCAGAATAAGAAACCAATCTGTGTCTCATCTTGCCCTCTGCGGGCATTAGATTTCGGCCCTATAGATGAACTT
AGAGCGAAATATGGCGAGTTTGCTGATATTGCTCCACTGCCAGACTCTTCTCTAACAAAGCCTTCACTGGTGATAAAACC
TAACCGTCACGCTAAACCTACAGGTGATAAGAGTGGTGCGCTTTGTAATAAGGCGGAGCTTTAA

Upstream 100 bases:

>100_bases
CAGCTCACAACCACACTAACTATGTGGAAATCCCTTATAGAAGCCTATCTGACCATTACCTAGTATTCGACTAAATTACT
CCCCAACTTTGGTCGTCAGT

Downstream 100 bases:

>100_bases
TCATGCATGAAATCCCATTAGTGATCTTTACTGTGCTTGCCCAAGCGGTAGCTGGTAGCTTTATCCTGCTATGTGCCCTG
CGTCTAGCATACCCTCAGCA

Product: dimethylsulfoxide reductase chain B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKLEYGFYVDSSKCTGCKTCQVACKDKNELPIGVNYRRVYEYAGGEWLKGLDDTWQQNVFAYYLSISCNHCAEPACTKAC
PTGAMHKRSQDGLVVVDTDVCIGCRYCEMACPYGAPQYNPEKKHMTKCDGCYELLAQNKKPICVSSCPLRALDFGPIDEL
RAKYGEFADIAPLPDSSLTKPSLVIKPNRHAKPTGDKSGALCNKAEL

Sequences:

>Translated_207_residues
MKLEYGFYVDSSKCTGCKTCQVACKDKNELPIGVNYRRVYEYAGGEWLKGLDDTWQQNVFAYYLSISCNHCAEPACTKAC
PTGAMHKRSQDGLVVVDTDVCIGCRYCEMACPYGAPQYNPEKKHMTKCDGCYELLAQNKKPICVSSCPLRALDFGPIDEL
RAKYGEFADIAPLPDSSLTKPSLVIKPNRHAKPTGDKSGALCNKAEL
>Mature_207_residues
MKLEYGFYVDSSKCTGCKTCQVACKDKNELPIGVNYRRVYEYAGGEWLKGLDDTWQQNVFAYYLSISCNHCAEPACTKAC
PTGAMHKRSQDGLVVVDTDVCIGCRYCEMACPYGAPQYNPEKKHMTKCDGCYELLAQNKKPICVSSCPLRALDFGPIDEL
RAKYGEFADIAPLPDSSLTKPSLVIKPNRHAKPTGDKSGALCNKAEL

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=207, Percent_Identity=67.6328502415459, Blast_Score=303, Evalue=4e-84,
Organism=Escherichia coli, GI1787872, Length=207, Percent_Identity=66.6666666666667, Blast_Score=300, Evalue=4e-83,
Organism=Escherichia coli, GI2367345, Length=195, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787749, Length=167, Percent_Identity=32.3353293413174, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1790326, Length=170, Percent_Identity=31.7647058823529, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI226510944, Length=161, Percent_Identity=39.1304347826087, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789370, Length=185, Percent_Identity=34.0540540540541, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787478, Length=99, Percent_Identity=37.3737373737374, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787740, Length=99, Percent_Identity=36.3636363636364, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787963, Length=153, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI2367245, Length=157, Percent_Identity=26.7515923566879, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI87082179, Length=159, Percent_Identity=30.188679245283, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788811, Length=156, Percent_Identity=26.2820512820513, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789067, Length=182, Percent_Identity=28.021978021978, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22875; Mature: 22875

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
8.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEYGFYVDSSKCTGCKTCQVACKDKNELPIGVNYRRVYEYAGGEWLKGLDDTWQQNVF
CEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHEEECCCCHHHHCCHHHHHHCEE
AYYLSISCNHCAEPACTKACPTGAMHKRSQDGLVVVDTDVCIGCRYCEMACPYGAPQYNP
EEEEEECCCCCCCCCHHHCCCCCHHHCCCCCCEEEEECCCEECCHHHHHCCCCCCCCCCC
EKKHMTKCDGCYELLAQNKKPICVSSCPLRALDFGPIDELRAKYGEFADIAPLPDSSLTK
CHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
PSLVIKPNRHAKPTGDKSGALCNKAEL
CEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLEYGFYVDSSKCTGCKTCQVACKDKNELPIGVNYRRVYEYAGGEWLKGLDDTWQQNVF
CEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHEEECCCCHHHHCCHHHHHHCEE
AYYLSISCNHCAEPACTKACPTGAMHKRSQDGLVVVDTDVCIGCRYCEMACPYGAPQYNP
EEEEEECCCCCCCCCHHHCCCCCHHHCCCCCCEEEEECCCEECCHHHHHCCCCCCCCCCC
EKKHMTKCDGCYELLAQNKKPICVSSCPLRALDFGPIDELRAKYGEFADIAPLPDSSLTK
CHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
PSLVIKPNRHAKPTGDKSGALCNKAEL
CEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]