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The map label for this gene is yqhD [H]

Identifier: 167622287

GI number: 167622287

Start: 410170

End: 411327

Strand: Reverse

Name: yqhD [H]

Synonym: Shal_0346

Alternate gene names: 167622287

Gene position: 411327-410170 (Counterclockwise)

Preceding gene: 167622288

Following gene: 167622286

Centisome position: 7.87

GC content: 47.06

Gene sequence:

>1158_bases
ATGTACAGCTTCGATTATTACAACCCAACCCACATCTGCTTTGGTGAAGGCAAAATTGCCGAGCTAGATAACTTAGTCCC
ACAAGATGCAAAAGTTCTAGTCCTATTTGGCGGTAATAGCGCCAGAAGTACAGGTACACTCGATGAGGTTAAAGCTGCAC
TTAAGCAGCGTGAGGTTGTTGAGTTTGGTGGTATCGAGGCTAACCCAACCTACGAAACATTAATGCAAGCGGTCGATGTG
GTAAAACAGCAAAATATCGACTTCCTGTTGGCCGTTGGTGGTGGCTCGGTTATCGATGGCACTAAGTTTGTCGCTGCTGC
CGCACTATTTGAAGCTGAGCCATGGGACATACTTTTAAGTTGGGGCGAAAAAGTCACTCAGGCTATGCCATTCGGTACGG
TACTAACCTTGCCAGCCACTGGCTCAGAGATGAATAGTGCCAGCGTTGTCACTCGTAAAGAGTACCAATCAAAGCTGTCT
TTCATGAGCAATCACGTCTTTCCAAAATTCTCAGTATTAGACCCAAGCAAAACCTTCACACTGCCTGAGCGCCAAGTGGC
TAACGGGGTTGTCGATGCCTTTATTCACATCACAGAGCAATACCTTAACTACCCAGTTAATGCGCCAGTACAAGACAGAT
TCGCCGAAGGCTTGCTGCAAACCCTTATCGAATTAGGCCCAAAAGCATTAAGCCAACCTAAAGACTTTGATGTGCGCGCT
AACCTGATGTGGGTAGCAACCATGGCCCTGAGTGGCGTGATAGGCAAAGGTGTGCCACACGACTGGGCAACACATATGAT
TAGCCATGAGATCACCGTCCTTTACGGAATTGACCATGCGCGTACTATCGCGATGATTCTACCTGGCATGCTCGATGTTC
GCCGTGACGCTAAGCAAGAGAAGTTACTGCAATATGCCGATCGCGTTTGGGGCATTAACCAAGGCAGCAATGATGAAATC
ATCGATGCGGCTATCAGTAAAACCCGTGAGTTCTTCGAAACGATGGGCATTAAAACTCGCCTTTCAGACTACGACTTAGA
TAGTAGCAGTATCGATGAGATCATCAATAAACTTGAAGGCCACGGCATGACGGCACTGGGCGAAAATCAAGATGTTGATC
TGGCTATGAGCCGCAAGATTTTAGAACGTAACTTATAA

Upstream 100 bases:

>100_bases
ACTCAATGTTAGCGAGCGCAATAAGCCACTAGATCATTGGCCTACTAAGCTTTAAGTATTAATATCACTCGACGCACTGA
GCTCGACTATAGGAACGATT

Downstream 100 bases:

>100_bases
CCCCTAATAACCACACAGATACAAGCGTAAAAGAGACCTCAGCTAATTGGCAGGCATCACGTAACAAGGATGCCGCTAAT
TGGCAAACCAACAGATAAAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MYSFDYYNPTHICFGEGKIAELDNLVPQDAKVLVLFGGNSARSTGTLDEVKAALKQREVVEFGGIEANPTYETLMQAVDV
VKQQNIDFLLAVGGGSVIDGTKFVAAAALFEAEPWDILLSWGEKVTQAMPFGTVLTLPATGSEMNSASVVTRKEYQSKLS
FMSNHVFPKFSVLDPSKTFTLPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSQPKDFDVRA
NLMWVATMALSGVIGKGVPHDWATHMISHEITVLYGIDHARTIAMILPGMLDVRRDAKQEKLLQYADRVWGINQGSNDEI
IDAAISKTREFFETMGIKTRLSDYDLDSSSIDEIINKLEGHGMTALGENQDVDLAMSRKILERNL

Sequences:

>Translated_385_residues
MYSFDYYNPTHICFGEGKIAELDNLVPQDAKVLVLFGGNSARSTGTLDEVKAALKQREVVEFGGIEANPTYETLMQAVDV
VKQQNIDFLLAVGGGSVIDGTKFVAAAALFEAEPWDILLSWGEKVTQAMPFGTVLTLPATGSEMNSASVVTRKEYQSKLS
FMSNHVFPKFSVLDPSKTFTLPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSQPKDFDVRA
NLMWVATMALSGVIGKGVPHDWATHMISHEITVLYGIDHARTIAMILPGMLDVRRDAKQEKLLQYADRVWGINQGSNDEI
IDAAISKTREFFETMGIKTRLSDYDLDSSSIDEIINKLEGHGMTALGENQDVDLAMSRKILERNL
>Mature_385_residues
MYSFDYYNPTHICFGEGKIAELDNLVPQDAKVLVLFGGNSARSTGTLDEVKAALKQREVVEFGGIEANPTYETLMQAVDV
VKQQNIDFLLAVGGGSVIDGTKFVAAAALFEAEPWDILLSWGEKVTQAMPFGTVLTLPATGSEMNSASVVTRKEYQSKLS
FMSNHVFPKFSVLDPSKTFTLPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSQPKDFDVRA
NLMWVATMALSGVIGKGVPHDWATHMISHEITVLYGIDHARTIAMILPGMLDVRRDAKQEKLLQYADRVWGINQGSNDEI
IDAAISKTREFFETMGIKTRLSDYDLDSSSIDEIINKLEGHGMTALGENQDVDLAMSRKILERNL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=252, Percent_Identity=23.4126984126984, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789386, Length=384, Percent_Identity=58.8541666666667, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI48994951, Length=312, Percent_Identity=25.6410256410256, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082107, Length=284, Percent_Identity=25.7042253521127, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789163, Length=301, Percent_Identity=25.9136212624585, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537053, Length=300, Percent_Identity=24.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321181, Length=351, Percent_Identity=25.6410256410256, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24657991, Length=330, Percent_Identity=22.7272727272727, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42539; Mature: 42539

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSFDYYNPTHICFGEGKIAELDNLVPQDAKVLVLFGGNSARSTGTLDEVKAALKQREVV
CCCCCCCCCCEEEECCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
EFGGIEANPTYETLMQAVDVVKQQNIDFLLAVGGGSVIDGTKFVAAAALFEAEPWDILLS
HHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHH
WGEKVTQAMPFGTVLTLPATGSEMNSASVVTRKEYQSKLSFMSNHVFPKFSVLDPSKTFT
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
LPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSQPKDFDVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHH
NLMWVATMALSGVIGKGVPHDWATHMISHEITVLYGIDHARTIAMILPGMLDVRRDAKQE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
KLLQYADRVWGINQGSNDEIIDAAISKTREFFETMGIKTRLSDYDLDSSSIDEIINKLEG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHCC
HGMTALGENQDVDLAMSRKILERNL
CCCEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYSFDYYNPTHICFGEGKIAELDNLVPQDAKVLVLFGGNSARSTGTLDEVKAALKQREVV
CCCCCCCCCCEEEECCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
EFGGIEANPTYETLMQAVDVVKQQNIDFLLAVGGGSVIDGTKFVAAAALFEAEPWDILLS
HHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHH
WGEKVTQAMPFGTVLTLPATGSEMNSASVVTRKEYQSKLSFMSNHVFPKFSVLDPSKTFT
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
LPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSQPKDFDVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHH
NLMWVATMALSGVIGKGVPHDWATHMISHEITVLYGIDHARTIAMILPGMLDVRRDAKQE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
KLLQYADRVWGINQGSNDEIIDAAISKTREFFETMGIKTRLSDYDLDSSSIDEIINKLEG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHCC
HGMTALGENQDVDLAMSRKILERNL
CCCEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]