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The map label for this gene is hlyB [H]

Identifier: 167622000

GI number: 167622000

Start: 66300

End: 67958

Strand: Direct

Name: hlyB [H]

Synonym: Shal_0059

Alternate gene names: 167622000

Gene position: 66300-67958 (Clockwise)

Preceding gene: 167621999

Following gene: 167622004

Centisome position: 1.27

GC content: 45.93

Gene sequence:

>1659_bases
ATGGATTGGCTTGTTTCTTTGAGCATTAAACGAAAGTTGATGGCTGTAATGTTGGTATTTGGCTTTACCGGATGTGCAAT
TTTGGTAGATGTGGTGTTTCGCACTGCAGAGGTCGAACAGAGTTTTAATGAATACGATCAAGCGGCAGTTAATAGTCAGA
AGTACTTGTTATCAATTAGCCGTGATATGAACTACGTGTCACGTTTATCTCGTAGCATTATGTTGGGGGATGACTTTAGC
AAAAACTTTAACCTGCTAGAAACACGTATTCAGGATATTTATAAGCATTTCGATGATCTAGATACTTCGATTGACTTCAT
TGTTATGGATGCAGATCGACAACATATCTATCAGCTTACGAATAATTCTAAACAAGCCACTACAGCCTTTTTAGAAGATG
GCCGTACGCGAATGTTAGCACTGAAATCTGTCGAGCGTACACCAGAGGTCCTGCAAAAGGCATGGACGGAATACAGTAAG
GGGGCAAGCCCTTTTGCAAACGAGGCCAGACTAACATTTAAAAAGCTGACCGAGGGGGAAGCGCAACTTCGTTCACGGAT
TCAGGCTGAGGCAATCAGTGCTTTGGCATCTATGCGGTTGCAATTACTTGGTTTAACACTGGTCTCTTTTGCATTTGCCG
GTATTGTTTTGTTTTTTGTCTCCCGTGCGATTTTACGTTCTGTAGATAACATGCAGCAGTCCATTACCTCGATTGAAGCG
GACTCAGATCTTACTCGCCGAATTCAGATCACCTCTCAAGATGAATTAGGTCAATTATCGCAGTCGTTCAACTTGATGCT
CGATAAGTTTCAAGCAAGCTTACAAGGCGTTGCTGAAACGTCGACTTCGTTGGCTGAGTCGTCTCAAGGAATGGCTGCGA
TAACGGCTGATGCAGCTAACTCAGTACAAACTCAGCGTGACGAACTAGAGATGGTTGCAACTGCCATGAATGAGATGACA
GCAACAGTGGTTGAAGTGGCTAAAAATGCCAATGATGCTGCCGACGCCGCAGTGCAAACAGATGGTCAATCTCAAGCTGG
CTTGGCTGTGGTGAATAGTACGGTTGAAGCCATTGAGAATTTAGCTGTTGGTATTGAGCGTGCATCGCAGGTCGTTCATG
ACCTAGAGCGTGACAGTCATCAGATAGGCTCTATTTTGGACGTGATTAAAGGGATTTCTGAGCAGACTAACTTGTTAGCG
CTTAACGCGGCGATAGAAGCGGCGAGAGCGGGTGAGCAAGGGCGTGGATTTGCAGTGGTTGCCGATGAAGTGAGAACCTT
GGCGAGTCGTACTCAAGCGTCGACAGAAGAGATCCAAGCCATGATTGAGAAACTGCAGGGCGGCGCCAAGCTTGCTGCGA
GTGCGATGTCGGATAGTCGGCAGTATGTCGATGATAGCGTAAGTCATGCTCGCAGTGCGGGTGAGGCACTACAAAGTATC
GTTGTTGCAATTGCAACGATTACCGACATGAACACCCAGATTGCCACTGCTGCCGAGGAGCAAAGCACTGTATCTGAAGA
GATTAACGCAAATATCGTTAATATCAGCCATGCGGCAGAGCAAACAGCCAATGGCACGAATATTAGCTCTCAGGAGAGCG
AAAACTTAGCACATATGGCTAAGCGGCTGTCGGTATTGGTGCAAGAGTTTAAAATCTAA

Upstream 100 bases:

>100_bases
TATAGTCTTTATGTATTTATATCTCAATAACTTAAAAAGGCATGACTTATTCTGAGATCAAATAGCGCCTATGCGCAGGA
TGATTGTACGGAGTAGTAGA

Downstream 100 bases:

>100_bases
TAACTCATCTAAATAGTGGTCTTTCTTTTCTGAGGGCACAACTTGTGCGGGTAATGAGTGATTACCCGCGCTAGCCAGTT
ATAAACCAAACACGATCTTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MDWLVSLSIKRKLMAVMLVFGFTGCAILVDVVFRTAEVEQSFNEYDQAAVNSQKYLLSISRDMNYVSRLSRSIMLGDDFS
KNFNLLETRIQDIYKHFDDLDTSIDFIVMDADRQHIYQLTNNSKQATTAFLEDGRTRMLALKSVERTPEVLQKAWTEYSK
GASPFANEARLTFKKLTEGEAQLRSRIQAEAISALASMRLQLLGLTLVSFAFAGIVLFFVSRAILRSVDNMQQSITSIEA
DSDLTRRIQITSQDELGQLSQSFNLMLDKFQASLQGVAETSTSLAESSQGMAAITADAANSVQTQRDELEMVATAMNEMT
ATVVEVAKNANDAADAAVQTDGQSQAGLAVVNSTVEAIENLAVGIERASQVVHDLERDSHQIGSILDVIKGISEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRTLASRTQASTEEIQAMIEKLQGGAKLAASAMSDSRQYVDDSVSHARSAGEALQSI
VVAIATITDMNTQIATAAEEQSTVSEEINANIVNISHAAEQTANGTNISSQESENLAHMAKRLSVLVQEFKI

Sequences:

>Translated_552_residues
MDWLVSLSIKRKLMAVMLVFGFTGCAILVDVVFRTAEVEQSFNEYDQAAVNSQKYLLSISRDMNYVSRLSRSIMLGDDFS
KNFNLLETRIQDIYKHFDDLDTSIDFIVMDADRQHIYQLTNNSKQATTAFLEDGRTRMLALKSVERTPEVLQKAWTEYSK
GASPFANEARLTFKKLTEGEAQLRSRIQAEAISALASMRLQLLGLTLVSFAFAGIVLFFVSRAILRSVDNMQQSITSIEA
DSDLTRRIQITSQDELGQLSQSFNLMLDKFQASLQGVAETSTSLAESSQGMAAITADAANSVQTQRDELEMVATAMNEMT
ATVVEVAKNANDAADAAVQTDGQSQAGLAVVNSTVEAIENLAVGIERASQVVHDLERDSHQIGSILDVIKGISEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRTLASRTQASTEEIQAMIEKLQGGAKLAASAMSDSRQYVDDSVSHARSAGEALQSI
VVAIATITDMNTQIATAAEEQSTVSEEINANIVNISHAAEQTANGTNISSQESENLAHMAKRLSVLVQEFKI
>Mature_552_residues
MDWLVSLSIKRKLMAVMLVFGFTGCAILVDVVFRTAEVEQSFNEYDQAAVNSQKYLLSISRDMNYVSRLSRSIMLGDDFS
KNFNLLETRIQDIYKHFDDLDTSIDFIVMDADRQHIYQLTNNSKQATTAFLEDGRTRMLALKSVERTPEVLQKAWTEYSK
GASPFANEARLTFKKLTEGEAQLRSRIQAEAISALASMRLQLLGLTLVSFAFAGIVLFFVSRAILRSVDNMQQSITSIEA
DSDLTRRIQITSQDELGQLSQSFNLMLDKFQASLQGVAETSTSLAESSQGMAAITADAANSVQTQRDELEMVATAMNEMT
ATVVEVAKNANDAADAAVQTDGQSQAGLAVVNSTVEAIENLAVGIERASQVVHDLERDSHQIGSILDVIKGISEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRTLASRTQASTEEIQAMIEKLQGGAKLAASAMSDSRQYVDDSVSHARSAGEALQSI
VVAIATITDMNTQIATAAEEQSTVSEEINANIVNISHAAEQTANGTNISSQESENLAHMAKRLSVLVQEFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=351, Percent_Identity=32.4786324786325, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=33.134328358209, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787690, Length=370, Percent_Identity=29.4594594594595, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788194, Length=379, Percent_Identity=30.8707124010554, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789453, Length=364, Percent_Identity=27.1978021978022, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60052; Mature: 60052

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWLVSLSIKRKLMAVMLVFGFTGCAILVDVVFRTAEVEQSFNEYDQAAVNSQKYLLSIS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RDMNYVSRLSRSIMLGDDFSKNFNLLETRIQDIYKHFDDLDTSIDFIVMDADRQHIYQLT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHH
NNSKQATTAFLEDGRTRMLALKSVERTPEVLQKAWTEYSKGASPFANEARLTFKKLTEGE
CCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHH
AQLRSRIQAEAISALASMRLQLLGLTLVSFAFAGIVLFFVSRAILRSVDNMQQSITSIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSDLTRRIQITSQDELGQLSQSFNLMLDKFQASLQGVAETSTSLAESSQGMAAITADAAN
CCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHH
SVQTQRDELEMVATAMNEMTATVVEVAKNANDAADAAVQTDGQSQAGLAVVNSTVEAIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LAVGIERASQVVHDLERDSHQIGSILDVIKGISEQTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEE
ADEVRTLASRTQASTEEIQAMIEKLQGGAKLAASAMSDSRQYVDDSVSHARSAGEALQSI
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAIATITDMNTQIATAAEEQSTVSEEINANIVNISHAAEQTANGTNISSQESENLAHMA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCCCCCCCCHHHHHHHHHH
KRLSVLVQEFKI
HHHHHHHHHHCC
>Mature Secondary Structure
MDWLVSLSIKRKLMAVMLVFGFTGCAILVDVVFRTAEVEQSFNEYDQAAVNSQKYLLSIS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RDMNYVSRLSRSIMLGDDFSKNFNLLETRIQDIYKHFDDLDTSIDFIVMDADRQHIYQLT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHH
NNSKQATTAFLEDGRTRMLALKSVERTPEVLQKAWTEYSKGASPFANEARLTFKKLTEGE
CCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHH
AQLRSRIQAEAISALASMRLQLLGLTLVSFAFAGIVLFFVSRAILRSVDNMQQSITSIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSDLTRRIQITSQDELGQLSQSFNLMLDKFQASLQGVAETSTSLAESSQGMAAITADAAN
CCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHH
SVQTQRDELEMVATAMNEMTATVVEVAKNANDAADAAVQTDGQSQAGLAVVNSTVEAIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LAVGIERASQVVHDLERDSHQIGSILDVIKGISEQTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEE
ADEVRTLASRTQASTEEIQAMIEKLQGGAKLAASAMSDSRQYVDDSVSHARSAGEALQSI
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAIATITDMNTQIATAAEEQSTVSEEINANIVNISHAAEQTANGTNISSQESENLAHMA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCCCCCCCCHHHHHHHHHH
KRLSVLVQEFKI
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]