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The map label for this gene is lnt

Identifier: 16752387

GI number: 16752387

Start: 105095

End: 106720

Strand: Direct

Name: lnt

Synonym: CP0094

Alternate gene names: 16752387

Gene position: 105095-106720 (Clockwise)

Preceding gene: 16752386

Following gene: 16752388

Centisome position: 8.55

GC content: 42.44

Gene sequence:

>1626_bases
GTGCTACGAATCTTTTGCTTTGTTATTTCTTGGTGCCTTATAGCTTTTGCTCAACCAGATTTAAGTGGATTCGTTTCCAT
ATTAGGAGCCGCCTGTGGTTATGGATTCTTTTGGTATAGTCTAGAACCCTTAAAAAAACCCTCATTACCTCTAAGGACTC
TTTTTGTATCCTGTTTTTTCTGGATCTTCACAATAGAGGGGATTCATTTTTCTTGGATGCTCTCGGATCAATATATAGGC
AAACTCATCTATTTGGTATGGCTTACATTAATCACGATTTTGTCCGTTCTATTTTCAGGATTTTCTTGCCTTCTAGTTGC
AATCGTACGTCAGAAACGCACAGCTTTTTTATGGAGCCTTCCTGGCGTATGGGTCGCTATCGAGATGCTTCGATTTTATG
GGATCTTTTCTGGGATGTCCTTCGATTATCTTGGTTGGCCTATGACAGCCTCTGCTTATGGACGGCAGTTTGGCGGATTT
TTGGGGTGGGCAGGTCAGAGCTTCGCTGTCATAGCTGTAAATATGAGCTTTTATTGTCTACTACTGAAAAAACCTCATGC
TAAAATGTTATGGGTGCTCACTCTTCTTTTGCCCTATACTTTTGGAGCAATTCATTATGAGTATCTTAAACACGCGTTTC
AACAAGATAAGAGAGCGCTGCGTGTCGCTGTTGTTCAACCCGCGCATCCCCCCATACGACCGAAACTTAAGTCCCCAATA
GTCGTCTGGGAACAACTCCTCCAACTCGTATCCCCAATACAACAACCCATAGATTTGCTGATTTTCCCAGAAGTAGTCGT
GCCTTTTGGTAAGCATAGGCAAGTCTATCCCTATGAATCCTGCGCACATTTATTGTCTTCTTTTGCTCCACTTCCCGAAG
GTAAGGCATTTCTATCGAATAGTGATTGTGCCACAGCTCTGTCACAACACTTTCAGTGTCCAGTAATTATTGGCTTAGAA
CGGTGGGTGAAAAAAGAGAACGTTTTGTATTGGTATAACTCTGCTGAGGTAATATCACACAAAGGAATTTCCGTAGGATA
CGATAAGCGTATCCTTGTGCCTGGTGGCGAATATATACCAGGAGGGAAATTCGGATCCCTAATTTGTAGACAACTATTTC
CTAAATATGCTCTAGGATGCAAGAGACTTCCAGGTAGACGTTCTGGAGTTGTGCAGGTCCGAGGTTTACCTCGTATCGGG
ATCACCATTTGCTACGAAGAAACTTTCGGCTATCGGTTGCAATCCTACAAGAGACAAGGAGCCGAACTCCTTGTTAACTT
AACAAATGACGGATGGTATCCTGAATCACGACTCCCTAAAGTCCATTTCCTCCATGGGATGTTGAGAAATCAAGAGTTTG
GGATGCCTTGCGTGCGAGCTTGCCAAACTGGTGTTACAGCAGCTGTGGATTCTCTAGGTCGAATACTCAAAATTCTTCCT
TATGATACTAGAGAAACTAAAGCCCCCTCAGGGGTATTGGAAACCTCTTTGCCTCTATTTAATTATAAAACGCTTTATGG
GTATTGTGGAGATTACCCTATGATTTTGATAGCTTTCTGTGCAGTCAGTTATCTAGGAGGAGGATTCTTAGGATATCGCT
TGCTTGCTAAAAAAGAAATTCGATAA

Upstream 100 bases:

>100_bases
TGTCCATCAGATTGTTCCAGAAACTCCAGAAGAAAAACGTCGGTATAATGAAGCAGATCGACGACGTCAAGCAAGGCTTG
AACTGAAATAAGGAGAGCCT

Downstream 100 bases:

>100_bases
TATACGGAGACTCGTTGTCAGGTTTTTACATGTTAGAACGAACTCAAAGAACGTTAAAGCGAGAGGTTCGCTATTCTGGA
GTGGGAATTCACTTAGGGAA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MLRIFCFVISWCLIAFAQPDLSGFVSILGAACGYGFFWYSLEPLKKPSLPLRTLFVSCFFWIFTIEGIHFSWMLSDQYIG
KLIYLVWLTLITILSVLFSGFSCLLVAIVRQKRTAFLWSLPGVWVAIEMLRFYGIFSGMSFDYLGWPMTASAYGRQFGGF
LGWAGQSFAVIAVNMSFYCLLLKKPHAKMLWVLTLLLPYTFGAIHYEYLKHAFQQDKRALRVAVVQPAHPPIRPKLKSPI
VVWEQLLQLVSPIQQPIDLLIFPEVVVPFGKHRQVYPYESCAHLLSSFAPLPEGKAFLSNSDCATALSQHFQCPVIIGLE
RWVKKENVLYWYNSAEVISHKGISVGYDKRILVPGGEYIPGGKFGSLICRQLFPKYALGCKRLPGRRSGVVQVRGLPRIG
ITICYEETFGYRLQSYKRQGAELLVNLTNDGWYPESRLPKVHFLHGMLRNQEFGMPCVRACQTGVTAAVDSLGRILKILP
YDTRETKAPSGVLETSLPLFNYKTLYGYCGDYPMILIAFCAVSYLGGGFLGYRLLAKKEIR

Sequences:

>Translated_541_residues
MLRIFCFVISWCLIAFAQPDLSGFVSILGAACGYGFFWYSLEPLKKPSLPLRTLFVSCFFWIFTIEGIHFSWMLSDQYIG
KLIYLVWLTLITILSVLFSGFSCLLVAIVRQKRTAFLWSLPGVWVAIEMLRFYGIFSGMSFDYLGWPMTASAYGRQFGGF
LGWAGQSFAVIAVNMSFYCLLLKKPHAKMLWVLTLLLPYTFGAIHYEYLKHAFQQDKRALRVAVVQPAHPPIRPKLKSPI
VVWEQLLQLVSPIQQPIDLLIFPEVVVPFGKHRQVYPYESCAHLLSSFAPLPEGKAFLSNSDCATALSQHFQCPVIIGLE
RWVKKENVLYWYNSAEVISHKGISVGYDKRILVPGGEYIPGGKFGSLICRQLFPKYALGCKRLPGRRSGVVQVRGLPRIG
ITICYEETFGYRLQSYKRQGAELLVNLTNDGWYPESRLPKVHFLHGMLRNQEFGMPCVRACQTGVTAAVDSLGRILKILP
YDTRETKAPSGVLETSLPLFNYKTLYGYCGDYPMILIAFCAVSYLGGGFLGYRLLAKKEIR
>Mature_541_residues
MLRIFCFVISWCLIAFAQPDLSGFVSILGAACGYGFFWYSLEPLKKPSLPLRTLFVSCFFWIFTIEGIHFSWMLSDQYIG
KLIYLVWLTLITILSVLFSGFSCLLVAIVRQKRTAFLWSLPGVWVAIEMLRFYGIFSGMSFDYLGWPMTASAYGRQFGGF
LGWAGQSFAVIAVNMSFYCLLLKKPHAKMLWVLTLLLPYTFGAIHYEYLKHAFQQDKRALRVAVVQPAHPPIRPKLKSPI
VVWEQLLQLVSPIQQPIDLLIFPEVVVPFGKHRQVYPYESCAHLLSSFAPLPEGKAFLSNSDCATALSQHFQCPVIIGLE
RWVKKENVLYWYNSAEVISHKGISVGYDKRILVPGGEYIPGGKFGSLICRQLFPKYALGCKRLPGRRSGVVQVRGLPRIG
ITICYEETFGYRLQSYKRQGAELLVNLTNDGWYPESRLPKVHFLHGMLRNQEFGMPCVRACQTGVTAAVDSLGRILKILP
YDTRETKAPSGVLETSLPLFNYKTLYGYCGDYPMILIAFCAVSYLGGGFLGYRLLAKKEIR

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=184, Percent_Identity=29.3478260869565, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_CHLPN (Q9Z7Q1)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B86572
- PIR:   F72051
- RefSeq:   NP_224849.1
- RefSeq:   NP_300709.1
- RefSeq:   NP_444646.1
- RefSeq:   NP_876951.1
- ProteinModelPortal:   Q9Z7Q1
- GeneID:   1467358
- GeneID:   895279
- GeneID:   919414
- GeneID:   962689
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0094
- KEGG:   cpj:CPj0653
- KEGG:   cpn:CPn0653
- KEGG:   cpt:CpB0679
- TIGR:   CP_0094
- HOGENOM:   HBG402731
- OMA:   GRQFGGF
- ProtClustDB:   PRK00302
- BioCyc:   CPNE115711:CP_0094-MONOMER
- BioCyc:   CPNE115713:CPN0653-MONOMER
- BioCyc:   CPNE138677:CPJ0653-MONOMER
- BioCyc:   CPNE182082:CPB0679-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 61261; Mature: 61261

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50263 CN_HYDROLASE; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb41f0f0)-; HASH(0x403a5ccc)-; HASH(0xb413af8)-; HASH(0x403b8770)-; HASH(0x403a5cfc)-; HASH(0xb42a8a8)-; HASH(0xb40ac18)-; HASH(0x4039e5c8)-;

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIFCFVISWCLIAFAQPDLSGFVSILGAACGYGFFWYSLEPLKKPSLPLRTLFVSCFF
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHH
WIFTIEGIHFSWMLSDQYIGKLIYLVWLTLITILSVLFSGFSCLLVAIVRQKRTAFLWSL
HHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
PGVWVAIEMLRFYGIFSGMSFDYLGWPMTASAYGRQFGGFLGWAGQSFAVIAVNMSFYCL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCEEEEEEECEEEEE
LLKKPHAKMLWVLTLLLPYTFGAIHYEYLKHAFQQDKRALRVAVVQPAHPPIRPKLKSPI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCH
VVWEQLLQLVSPIQQPIDLLIFPEVVVPFGKHRQVYPYESCAHLLSSFAPLPEGKAFLSN
HHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECC
SDCATALSQHFQCPVIIGLERWVKKENVLYWYNSAEVISHKGISVGYDKRILVPGGEYIP
CHHHHHHHHCCCCCEEECHHHHHCCCCEEEEECCCHHHHCCCCEECCCCEEECCCCCCCC
GGKFGSLICRQLFPKYALGCKRLPGRRSGVVQVRGLPRIGITICYEETFGYRLQSYKRQG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEECHHHHHHHHHHHCC
AELLVNLTNDGWYPESRLPKVHFLHGMLRNQEFGMPCVRACQTGVTAAVDSLGRILKILP
CEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
YDTRETKAPSGVLETSLPLFNYKTLYGYCGDYPMILIAFCAVSYLGGGFLGYRLLAKKEI
CCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
R
H
>Mature Secondary Structure
MLRIFCFVISWCLIAFAQPDLSGFVSILGAACGYGFFWYSLEPLKKPSLPLRTLFVSCFF
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHH
WIFTIEGIHFSWMLSDQYIGKLIYLVWLTLITILSVLFSGFSCLLVAIVRQKRTAFLWSL
HHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
PGVWVAIEMLRFYGIFSGMSFDYLGWPMTASAYGRQFGGFLGWAGQSFAVIAVNMSFYCL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCEEEEEEECEEEEE
LLKKPHAKMLWVLTLLLPYTFGAIHYEYLKHAFQQDKRALRVAVVQPAHPPIRPKLKSPI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCH
VVWEQLLQLVSPIQQPIDLLIFPEVVVPFGKHRQVYPYESCAHLLSSFAPLPEGKAFLSN
HHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECC
SDCATALSQHFQCPVIIGLERWVKKENVLYWYNSAEVISHKGISVGYDKRILVPGGEYIP
CHHHHHHHHCCCCCEEECHHHHHCCCCEEEEECCCHHHHCCCCEECCCCEEECCCCCCCC
GGKFGSLICRQLFPKYALGCKRLPGRRSGVVQVRGLPRIGITICYEETFGYRLQSYKRQG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEECHHHHHHHHHHHCC
AELLVNLTNDGWYPESRLPKVHFLHGMLRNQEFGMPCVRACQTGVTAAVDSLGRILKILP
CEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
YDTRETKAPSGVLETSLPLFNYKTLYGYCGDYPMILIAFCAVSYLGGGFLGYRLLAKKEI
CCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
R
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362