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Identifier: 16752361

GI number: 16752361

Start: 77336

End: 78616

Strand: Direct

Name: Not Available

Synonym: CP0067

Alternate gene names: 16752361

Gene position: 77336-78616 (Clockwise)

Preceding gene: 16752360

Following gene: 16752362

Centisome position: 6.29

GC content: 42.86

Gene sequence:

>1281_bases
ATGCTTCCATTAATCATTTTTGTCCTTCTATGTGGCTTTTATACTTCTTGGAATATAGGAGCTAATGATGTCGCTAATGC
TGTAGGCCCTAGTGTAGGATCTGGGGTATTGACATTGCGACAAGCCGTGGTCATCGCTGCTATCTTTGAGTTTTTTGGTG
CTCTCCTTCTTGGAGATCGTGTTGCAGGGACTATAGAAAGTAGTATCGTTTCTGTGACCAATCCTATGATTGCCTCTGGG
GACTATATGTACGGCATGACGGCAGCCTTACTAGCAACAGGCGTGTGGTTGCAGCTGGCCTCTTTTTTTGGTTGGCCCGT
CTCAACAACGCATTCTATAGTTGGAGCTGTGATTGGCTTTGGATTGGTCCTTGGTAAGGGAACAATCATTTACTGGAATT
CCGTAGGCATTATTTTAATTAGCTGGATTCTCTCCCCTTTTATGGGTGGGTGTGTTGCTTACCTGATCTTTTCTTTCATT
CGGCGCCATATTTTTTATAAGAATGATCCTGTTCTTGCTATGGTTCGTGTTGCTCCGTTTTTAGCAGCTTTGGTGATCAT
GACTTTAGGAACCGTGATGATCTCTGGGGGCGTGATCCTTAAGGTTTCTTCAACTCCCTGGGCAGTTAGTGGGGTTCTGG
TTTGTGGACTTCTAAGTTATATCATTACGTTTTACTACGTCCATACCAAGCACTGTTCCTACATTTCAGATACACCAAAA
AAAGGCAGTCTTACCTATCGTTTGAAAGAACGAGGCGGAAATTATGGAAGAAAGTATCTTGTTGTAGAAAGAATCTTTGC
CTACCTACAGATTATCGTAGCTTGCTTTATGGCGTTTGCTCACGGATCTAATGATGTTGCTAATGCCATTGCTCCTGTAG
CTGGAGTCTTGCGTCAGGCATATCCTGCTTCCTATACGTCGTATACATTAATTAGGCTCATGGCATTTGGAGGCATAGGC
TTGGTCATAGGCCTTGCGATTTGGGGATGGCGTGTTATAGAAACTGTAGGCTGTAAAATTACCGAGTTAACCCCGTCTCG
AGGGTTTTCCGTGGGGATGGGCTCAGCATTAACAATTGCTTTAGCTTCTATTTTAGGACTTCCTATATCTACGACACATG
TTGTTGTTGGAGCTGTTTTAGGAATAGGTTTAGCACGAGGGATCCGTGCCATTAACTTAAACATTATCAAAGATATTGTA
CTCTCCTGGTTTATTACGCTTCCTGCAGGAGCTTTATTATCCATACTCTTTTTCTTTGCTTTAAGAGCTTTGTTCCATTA
A

Upstream 100 bases:

>100_bases
TCTTTGGTTACAAGTAATTCGACGCACTGCGGGGATTTCAGATAGTTCTGAAAAGCTCGCACATAGAATTAATATGACCC
TAGAAGAAAAGTAATACTCC

Downstream 100 bases:

>100_bases
AAATAAGAAAAATCAAATAGTAGGTTCTTGAGGATATATGGATAAGCTAACAGTACAAGATCTTTCTCCAGAAGAAAAAA
AAGTCCTCGTACGTGTAGAT

Product: phosphate permease family protein

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MLPLIIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFFGALLLGDRVAGTIESSIVSVTNPMIASG
DYMYGMTAALLATGVWLQLASFFGWPVSTTHSIVGAVIGFGLVLGKGTIIYWNSVGIILISWILSPFMGGCVAYLIFSFI
RRHIFYKNDPVLAMVRVAPFLAALVIMTLGTVMISGGVILKVSSTPWAVSGVLVCGLLSYIITFYYVHTKHCSYISDTPK
KGSLTYRLKERGGNYGRKYLVVERIFAYLQIIVACFMAFAHGSNDVANAIAPVAGVLRQAYPASYTSYTLIRLMAFGGIG
LVIGLAIWGWRVIETVGCKITELTPSRGFSVGMGSALTIALASILGLPISTTHVVVGAVLGIGLARGIRAINLNIIKDIV
LSWFITLPAGALLSILFFFALRALFH

Sequences:

>Translated_426_residues
MLPLIIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFFGALLLGDRVAGTIESSIVSVTNPMIASG
DYMYGMTAALLATGVWLQLASFFGWPVSTTHSIVGAVIGFGLVLGKGTIIYWNSVGIILISWILSPFMGGCVAYLIFSFI
RRHIFYKNDPVLAMVRVAPFLAALVIMTLGTVMISGGVILKVSSTPWAVSGVLVCGLLSYIITFYYVHTKHCSYISDTPK
KGSLTYRLKERGGNYGRKYLVVERIFAYLQIIVACFMAFAHGSNDVANAIAPVAGVLRQAYPASYTSYTLIRLMAFGGIG
LVIGLAIWGWRVIETVGCKITELTPSRGFSVGMGSALTIALASILGLPISTTHVVVGAVLGIGLARGIRAINLNIIKDIV
LSWFITLPAGALLSILFFFALRALFH
>Mature_426_residues
MLPLIIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFFGALLLGDRVAGTIESSIVSVTNPMIASG
DYMYGMTAALLATGVWLQLASFFGWPVSTTHSIVGAVIGFGLVLGKGTIIYWNSVGIILISWILSPFMGGCVAYLIFSFI
RRHIFYKNDPVLAMVRVAPFLAALVIMTLGTVMISGGVILKVSSTPWAVSGVLVCGLLSYIITFYYVHTKHCSYISDTPK
KGSLTYRLKERGGNYGRKYLVVERIFAYLQIIVACFMAFAHGSNDVANAIAPVAGVLRQAYPASYTSYTLIRLMAFGGIG
LVIGLAIWGWRVIETVGCKITELTPSRGFSVGMGSALTIALASILGLPISTTHVVVGAVLGIGLARGIRAINLNIIKDIV
LSWFITLPAGALLSILFFFALRALFH

Specific function: Potential transporter for phosphate

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family

Homologues:

Organism=Homo sapiens, GI31543630, Length=215, Percent_Identity=36.7441860465116, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI5803173, Length=155, Percent_Identity=40.6451612903226, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25146401, Length=442, Percent_Identity=31.447963800905, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71981576, Length=433, Percent_Identity=33.7182448036951, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI32566716, Length=465, Percent_Identity=32.0430107526882, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17539280, Length=507, Percent_Identity=29.7830374753452, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17536725, Length=468, Percent_Identity=27.7777777777778, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17557328, Length=489, Percent_Identity=24.9488752556237, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319773, Length=168, Percent_Identity=36.3095238095238, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356511, Length=204, Percent_Identity=40.1960784313725, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y680_CHLPN (Q9Z7M4)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D72049
- PIR:   E86575
- RefSeq:   NP_224876.1
- RefSeq:   NP_300736.1
- RefSeq:   NP_444619.1
- RefSeq:   NP_876979.1
- GeneID:   1467386
- GeneID:   895403
- GeneID:   919439
- GeneID:   963720
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0067
- KEGG:   cpj:CPj0680
- KEGG:   cpn:CPn0680
- KEGG:   cpt:CpB0707
- TIGR:   CP_0067
- HOGENOM:   HBG681698
- OMA:   RNGIIDS
- PhylomeDB:   Q9Z7M4
- ProtClustDB:   CLSK871542
- BioCyc:   CPNE115711:CP_0067-MONOMER
- BioCyc:   CPNE115713:CPN0680-MONOMER
- BioCyc:   CPNE138677:CPJ0680-MONOMER
- BioCyc:   CPNE182082:CPB0707-MONOMER
- InterPro:   IPR001204
- PANTHER:   PTHR11101

Pfam domain/function: PF01384 PHO4

EC number: NA

Molecular weight: Translated: 45561; Mature: 45561

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x9466eb4)-; HASH(0xbbfb6cc)-; HASH(0xba518c8)-; HASH(0xb84403c)-; HASH(0xba51958)-; HASH(0xb8adaf8)-; HASH(0xba2229c)-; HASH(0xae903a0)-; HASH(0xae5ef80)-; HASH(0xc3d2214)-; HASH(0xbdaf3c0)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLIIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFFGALLLGDR
CHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
VAGTIESSIVSVTNPMIASGDYMYGMTAALLATGVWLQLASFFGWPVSTTHSIVGAVIGF
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GLVLGKGTIIYWNSVGIILISWILSPFMGGCVAYLIFSFIRRHIFYKNDPVLAMVRVAPF
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LAALVIMTLGTVMISGGVILKVSSTPWAVSGVLVCGLLSYIITFYYVHTKHCSYISDTPK
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KGSLTYRLKERGGNYGRKYLVVERIFAYLQIIVACFMAFAHGSNDVANAIAPVAGVLRQA
CCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YPASYTSYTLIRLMAFGGIGLVIGLAIWGWRVIETVGCKITELTPSRGFSVGMGSALTIA
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHH
LASILGLPISTTHVVVGAVLGIGLARGIRAINLNIIKDIVLSWFITLPAGALLSILFFFA
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LRALFH
HHHHCH
>Mature Secondary Structure
MLPLIIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFFGALLLGDR
CHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
VAGTIESSIVSVTNPMIASGDYMYGMTAALLATGVWLQLASFFGWPVSTTHSIVGAVIGF
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GLVLGKGTIIYWNSVGIILISWILSPFMGGCVAYLIFSFIRRHIFYKNDPVLAMVRVAPF
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LAALVIMTLGTVMISGGVILKVSSTPWAVSGVLVCGLLSYIITFYYVHTKHCSYISDTPK
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KGSLTYRLKERGGNYGRKYLVVERIFAYLQIIVACFMAFAHGSNDVANAIAPVAGVLRQA
CCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YPASYTSYTLIRLMAFGGIGLVIGLAIWGWRVIETVGCKITELTPSRGFSVGMGSALTIA
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHH
LASILGLPISTTHVVVGAVLGIGLARGIRAINLNIIKDIVLSWFITLPAGALLSILFFFA
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LRALFH
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362