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Identifier: 16752333

GI number: 16752333

Start: 46556

End: 47884

Strand: Direct

Name: Not Available

Synonym: CP0039

Alternate gene names: 16752333

Gene position: 46556-47884 (Clockwise)

Preceding gene: 16752332

Following gene: 16752334

Centisome position: 3.79

GC content: 45.82

Gene sequence:

>1329_bases
ATGGATCAGTTAACAACGGATTTCGACACTCTCATGTCACAACTTGGTGATGTGAATCTTACGACTGTAGTAGGCCGCAT
TACAGAAGTGGTCGGCATGTTAATCAAAGCCGTAGTTCCTAATGTGCGTGTTGGAGAAGTATGCTTAGTGAAACGTAACG
GCATGGAACCTCTCGTAACAGAAGTCGTTGGTTTTACCCAGAGTTTTGCCTTTCTCTCTCCTTTAGGAGAGTTATCAGGA
GTGAGTCCTTCTTCCGAAGTCATCCCTACAGGACTCCCCTTACACATTCGAGCAGGAAACGGCCTCTTAGGTCGTGTTCT
CAATGGGTTGGGAGAACCCATAGATGTAGAAACTAAAGGTCCATTACAAAATGTGGATCAAACATTTCCTATTTTTCGTG
CACCCCCAGATCCCCTGCATAGGGCGAAATTACGACAGATCCTGTCTACGGGTGTGCGTTGTATAGACGGTATGCTCACG
GTCGCTAGGGGGCAGCGTATTGGAATTTTTGCTGGTGCTGGAGTGGGAAAATCTTCGCTCTTAGGTATGATCGCAAGAAA
CGCTGAAGAAGCCGACGTTAATGTAATCGCGCTTATTGGAGAAAGGGGGCGTGAAGTACGTGAGTTTATAGAGGGGGATT
TGGGAGAAGAAGGAATGAAACGTTCCGTAATTGTCGTTTCTACTTCTGACCAATCGTCGCAATTGCGACTTAATGCCGCC
TATGTAGGGACTGCAATTGCAGAGTATTTTCGTGATCAAGGGAAAACTGTCGTACTTATGATGGATTCCGTGACACGATT
TGCTCGTGCATTGCGGGAAGTGGGGTTAGCCGCTGGAGAGCCTCCTGCTAGAGCAGGATACACTCCATCGGTTTTTTCCA
CTCTACCCCGTCTATTGGAAAGATCAGGAGCCTCCGATAAAGGAACCATTACAGCATTTTATACCGTCTTGGTAGCAGGA
GATGATATGAACGAGCCTGTTGCTGACGAAGTCAAATCGATTCTTGACGGGCATATTGTTCTCTCCAATGCACTAGCTCA
AGCATACCATTATCCTGCAATTGACGTACTTGCTTCGATTAGCCGACTCCTGACTGCTATTGTTCCTGAAGAACAACGAC
GGATCATAGGGAAAGCAAGAGAAGTTTTAGCTAAATATAAAGCCAACGAGATGTTGATCCGTATTGGAGAATACCGACGA
GGTTCTGATCGTGAGATAGATTTTGCTATCGACCATATTGACAAATTGAACCGGTTTTTAAAGCAAGATATCCACGAAAA
GACAAACTATGAGGAAGCAGCACAACAACTGCGCGCCATTTTCCGGTAA

Upstream 100 bases:

>100_bases
GCTGTGCAGCGAGCTACACAAAGAGCAGAACTGTTTGCGAGTATTGTCGGTACCTCTGTAAGTAGCGTGAAAACGATTAT
GACAACGCAATTAGGTTAAC

Downstream 100 bases:

>100_bases
ATAAAGAGTAGTATGCTGTGGCAAAATATCCACTAGAGCCTGTTTTAGCGATTAAAAAGGATCGTGTAGATAGAGCAGAA
AAAGTTGTTAAAGAAAAACG

Product: type III secretion system ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDQLTTDFDTLMSQLGDVNLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRNGMEPLVTEVVGFTQSFAFLSPLGELSG
VSPSSEVIPTGLPLHIRAGNGLLGRVLNGLGEPIDVETKGPLQNVDQTFPIFRAPPDPLHRAKLRQILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREIDFAIDHIDKLNRFLKQDIHEKTNYEEAAQQLRAIFR

Sequences:

>Translated_442_residues
MDQLTTDFDTLMSQLGDVNLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRNGMEPLVTEVVGFTQSFAFLSPLGELSG
VSPSSEVIPTGLPLHIRAGNGLLGRVLNGLGEPIDVETKGPLQNVDQTFPIFRAPPDPLHRAKLRQILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREIDFAIDHIDKLNRFLKQDIHEKTNYEEAAQQLRAIFR
>Mature_442_residues
MDQLTTDFDTLMSQLGDVNLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRNGMEPLVTEVVGFTQSFAFLSPLGELSG
VSPSSEVIPTGLPLHIRAGNGLLGRVLNGLGEPIDVETKGPLQNVDQTFPIFRAPPDPLHRAKLRQILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREIDFAIDHIDKLNRFLKQDIHEKTNYEEAAQQLRAIFR

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=353, Percent_Identity=32.5779036827195, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=30.1324503311258, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI50345984, Length=311, Percent_Identity=29.2604501607717, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI4757810, Length=311, Percent_Identity=29.2604501607717, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI19913426, Length=301, Percent_Identity=29.2358803986711, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI19913424, Length=257, Percent_Identity=29.1828793774319, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1788251, Length=451, Percent_Identity=46.3414634146341, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1790170, Length=408, Percent_Identity=30.8823529411765, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1790172, Length=384, Percent_Identity=29.1666666666667, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790217, Length=275, Percent_Identity=29.4545454545455, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144756, Length=348, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71988080, Length=356, Percent_Identity=27.8089887640449, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71988063, Length=356, Percent_Identity=27.8089887640449, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17510931, Length=287, Percent_Identity=29.616724738676, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=28.0936454849498, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71988074, Length=336, Percent_Identity=26.7857142857143, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17565854, Length=326, Percent_Identity=27.6073619631902, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=352, Percent_Identity=33.8068181818182, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319370, Length=356, Percent_Identity=28.6516853932584, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319603, Length=377, Percent_Identity=28.6472148541114, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6320016, Length=189, Percent_Identity=33.8624338624339, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24638766, Length=353, Percent_Identity=32.8611898016997, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28574560, Length=346, Percent_Identity=32.3699421965318, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24658560, Length=311, Percent_Identity=30.5466237942122, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281361666, Length=302, Percent_Identity=28.8079470198675, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24646341, Length=302, Percent_Identity=28.8079470198675, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136796, Length=302, Percent_Identity=28.8079470198675, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24583992, Length=257, Percent_Identity=29.9610894941634, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24583988, Length=257, Percent_Identity=29.9610894941634, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24583986, Length=257, Percent_Identity=29.9610894941634, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24583984, Length=257, Percent_Identity=29.9610894941634, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20129479, Length=256, Percent_Identity=30.859375, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 48107; Mature: 48107

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLTTDFDTLMSQLGDVNLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRNGMEPLVT
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHH
EVVGFTQSFAFLSPLGELSGVSPSSEVIPTGLPLHIRAGNGLLGRVLNGLGEPIDVETKG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCC
PLQNVDQTFPIFRAPPDPLHRAKLRQILSTGVRCIDGMLTVARGQRIGIFAGAGVGKSSL
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
LGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
HHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEHHH
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLE
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RSGASDKGTITAFYTVLVAGDDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASI
HCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
SRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRRGSDREIDFAIDHIDKLNRFL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHH
KQDIHEKTNYEEAAQQLRAIFR
HHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MDQLTTDFDTLMSQLGDVNLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRNGMEPLVT
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHH
EVVGFTQSFAFLSPLGELSGVSPSSEVIPTGLPLHIRAGNGLLGRVLNGLGEPIDVETKG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCC
PLQNVDQTFPIFRAPPDPLHRAKLRQILSTGVRCIDGMLTVARGQRIGIFAGAGVGKSSL
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
LGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
HHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEHHH
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLE
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RSGASDKGTITAFYTVLVAGDDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASI
HCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
SRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRRGSDREIDFAIDHIDKLNRFL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHH
KQDIHEKTNYEEAAQQLRAIFR
HHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]