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The map label for this gene is thrC [H]

Identifier: 167040924

GI number: 167040924

Start: 2330199

End: 2331254

Strand: Reverse

Name: thrC [H]

Synonym: Teth514_2310

Alternate gene names: 167040924

Gene position: 2331254-2330199 (Counterclockwise)

Preceding gene: 167040925

Following gene: 167040923

Centisome position: 94.87

GC content: 38.83

Gene sequence:

>1056_bases
ATGGGATGGGAAGGTCTAATAAAAGCTTATAGAGAATTTATGCCTAAAATAAAAGAGGAAAACATAGTTACATTAAAAGA
AGGCAATACACCTCTTTATGAGGCTGTAAATCTTCAAAAGCTTTTTCCAGGCATAAAAATATATCTGAAATACGAAGGAT
TAAACCCAACAGGTTCTTTTAAAGACAGGGGGATGACTGTAGCAGTGTCGCAGGCAAAAGAAGAAGGTTCTAATGCAGTT
GTGTGTGCTTCAACAGGAAACACTTCTGCTTCTGCAGCTGCCTATGCAGCAAAGGCAGGACTTAAGAGCATTGTACTTAT
ACCCGGCGGCAAAATTGCTTTAGGAAAGCTTGCTCAAGCCATTGCTTATGGTGCTAAAGTCATTGCTATAGATGGAAACT
TTGATGATGCTTTAAGATTAGTCAGAGAAATTTCACAAAAATTCCCTATAACGCTGGTTAATTCCATAAATCCATATAGG
TTGGAAGGACAAAAGACAGCTTCTTTTGAAATATGTGACGAACTTAAAGATGCTCCTTCTTATGTTGCGCTTCCTGTGGG
AAATGCGGGGAATATAACAGCCTATTGGATGGGATTTAAAGAATATTATAATGCAAAAAGAATAACGAGGCTTCCTAAAA
TGTTAGGTTTTCAGGCAGCTGGAGCTGCACCTATAGTTGAAAACAGAGTAATTGAAAAACCTGAGACTATTGCAACAGCG
ATACGAATAGGTAATCCAGCCAGCTGGGAAAAGGCAGTTGCTGCAAGAGATGAGTCAGGTGGACTCATTGACAAAGTCAC
AGATGAAGAAATACTGGAGGCTTATGCGCTTTTAGCTAAGAGCGAAGGAATTTTTGCAGAGCCTGCTTCAGCAGCTTCTA
TTGCAGGAGTTATTAAAAAATACAAGGAAGGATTTTTTAAAGAAGGAGAATCTGTTGTTTGTGTCTTGACGGGAAATGGA
TTAAAAGATCCAGATACTGCTGTTAAATTAGGTGGCGAGATAAAAACGATAGAGGCGAATCTAAAAGCATTGGAGGAAGT
TTTATATGGAGAGTGA

Upstream 100 bases:

>100_bases
TGCGAATACAGGGAAGGTATTTGAAGCCTTAGAGGAAATACAAAATCTGAAGGAAGTAGAATGTATAGAAAGTGTCATAA
GAGTAGAGGGGGAATAATTA

Downstream 100 bases:

>100_bases
CATGGTAAAGGTAAAAGTTCCAGCCTCTTCTGCAAACTTAGGGCCCGGTTTTGACTCTATAGGAGTAGCACTAAATTTGT
ATACAGAAATTTCTATGGGA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MGWEGLIKAYREFMPKIKEENIVTLKEGNTPLYEAVNLQKLFPGIKIYLKYEGLNPTGSFKDRGMTVAVSQAKEEGSNAV
VCASTGNTSASAAAYAAKAGLKSIVLIPGGKIALGKLAQAIAYGAKVIAIDGNFDDALRLVREISQKFPITLVNSINPYR
LEGQKTASFEICDELKDAPSYVALPVGNAGNITAYWMGFKEYYNAKRITRLPKMLGFQAAGAAPIVENRVIEKPETIATA
IRIGNPASWEKAVAARDESGGLIDKVTDEEILEAYALLAKSEGIFAEPASAASIAGVIKKYKEGFFKEGESVVCVLTGNG
LKDPDTAVKLGGEIKTIEANLKALEEVLYGE

Sequences:

>Translated_351_residues
MGWEGLIKAYREFMPKIKEENIVTLKEGNTPLYEAVNLQKLFPGIKIYLKYEGLNPTGSFKDRGMTVAVSQAKEEGSNAV
VCASTGNTSASAAAYAAKAGLKSIVLIPGGKIALGKLAQAIAYGAKVIAIDGNFDDALRLVREISQKFPITLVNSINPYR
LEGQKTASFEICDELKDAPSYVALPVGNAGNITAYWMGFKEYYNAKRITRLPKMLGFQAAGAAPIVENRVIEKPETIATA
IRIGNPASWEKAVAARDESGGLIDKVTDEEILEAYALLAKSEGIFAEPASAASIAGVIKKYKEGFFKEGESVVCVLTGNG
LKDPDTAVKLGGEIKTIEANLKALEEVLYGE
>Mature_350_residues
GWEGLIKAYREFMPKIKEENIVTLKEGNTPLYEAVNLQKLFPGIKIYLKYEGLNPTGSFKDRGMTVAVSQAKEEGSNAVV
CASTGNTSASAAAYAAKAGLKSIVLIPGGKIALGKLAQAIAYGAKVIAIDGNFDDALRLVREISQKFPITLVNSINPYRL
EGQKTASFEICDELKDAPSYVALPVGNAGNITAYWMGFKEYYNAKRITRLPKMLGFQAAGAAPIVENRVIEKPETIATAI
RIGNPASWEKAVAARDESGGLIDKVTDEEILEAYALLAKSEGIFAEPASAASIAGVIKKYKEGFFKEGESVVCVLTGNGL
KDPDTAVKLGGEIKTIEANLKALEEVLYGE

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=290, Percent_Identity=27.2413793103448, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37624; Mature: 37492

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWEGLIKAYREFMPKIKEENIVTLKEGNTPLYEAVNLQKLFPGIKIYLKYEGLNPTGSF
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCC
KDRGMTVAVSQAKEEGSNAVVCASTGNTSASAAAYAAKAGLKSIVLIPGGKIALGKLAQA
CCCCEEEEEECHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
IAYGAKVIAIDGNFDDALRLVREISQKFPITLVNSINPYRLEGQKTASFEICDELKDAPS
HHCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCHHHHHHHHCCCCC
YVALPVGNAGNITAYWMGFKEYYNAKRITRLPKMLGFQAAGAAPIVENRVIEKPETIATA
EEEEECCCCCCEEEEEECHHHHHCHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHH
IRIGNPASWEKAVAARDESGGLIDKVTDEEILEAYALLAKSEGIFAEPASAASIAGVIKK
EECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
YKEGFFKEGESVVCVLTGNGLKDPDTAVKLGGEIKTIEANLKALEEVLYGE
HHHHHHCCCCEEEEEEECCCCCCCCHHHEECCCEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
GWEGLIKAYREFMPKIKEENIVTLKEGNTPLYEAVNLQKLFPGIKIYLKYEGLNPTGSF
CHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCC
KDRGMTVAVSQAKEEGSNAVVCASTGNTSASAAAYAAKAGLKSIVLIPGGKIALGKLAQA
CCCCEEEEEECHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
IAYGAKVIAIDGNFDDALRLVREISQKFPITLVNSINPYRLEGQKTASFEICDELKDAPS
HHCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCHHHHHHHHCCCCC
YVALPVGNAGNITAYWMGFKEYYNAKRITRLPKMLGFQAAGAAPIVENRVIEKPETIATA
EEEEECCCCCCEEEEEECHHHHHCHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHH
IRIGNPASWEKAVAARDESGGLIDKVTDEEILEAYALLAKSEGIFAEPASAASIAGVIKK
EECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
YKEGFFKEGESVVCVLTGNGLKDPDTAVKLGGEIKTIEANLKALEEVLYGE
HHHHHHCCCCEEEEEEECCCCCCCCHHHEECCCEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3098560; 9384377; 3139660 [H]