Click here to switch to the map view.

The map label for this gene is yebQ [H]

Identifier: 167040847

GI number: 167040847

Start: 2229121

End: 2230518

Strand: Direct

Name: yebQ [H]

Synonym: Teth514_2227

Alternate gene names: 167040847

Gene position: 2229121-2230518 (Clockwise)

Preceding gene: 167040840

Following gene: 167040848

Centisome position: 90.72

GC content: 36.34

Gene sequence:

>1398_bases
ATGTCACAAAAACAGTACAACAAATGGTTAATTCTTTCTGCAGTTGTCATTGGTAGCATAATGGGGCCAATTGACGGAAG
TATAGTCAACATAGCAATGCCAGAATTTACAAAGATTTTCCACACAAATATAACAACAGTAAGCTGGGTCTCCATGACAT
ATTTATTAGTTTTAAGTAGTCTAATGATGACTTTTGGAAGACTTGGCGATATGTTGGGTTATAAAAAACTGTATCAATAC
GGCCTTTTGACTTTTTCAATATCTTCTGCGATCTTGAGTCTTTCTGTAAATATATATATGTTAATAATTATGCGAGCTTT
CCAAGCAATAGGAGCTGGCATGCTAATGTCAATGACATCAGCTATTATAACATCCGTGTTTCCTCCAAACGAAAGAGGTA
AAGCTCTCGGCATTAACGCTATGTCTATATCTATCGGGCTTGCAATAGGTCCTACATTAGGGGGTTTTCTTTTATCAAAT
TTGGGTTGGCAGTCTATATTTTATATAAACGTTCCTATCGGTATAATAGGTTACATATGGGCTCATATCGTGGTACCTGA
CAACAAAGGAGTTCCTGAAAAATTTGATATTTACGGATCTATTTCTTTCTTTGGCTTTCTTGCAAGCCTCTTGCTCTTTA
TATCAGAAGGTGGAACATGGGGTTGGACATCACTTCCAAGTATAATTTCATTATTGACATCAGTAACATTTTTAACAATC
TTTGTAATTATAGAAAATAAAGTAGACTTTCCTATGTTTGACTTCTCTCTTTTAAAAATAAGGTCTTTTACCTTTGGAAA
CATAAGCACCCTGCTAAACTTTATGTCTCAAAACACAATGACTTTTTTAACTCCTTTCCTCCTTCAGCATCTAGGATTTA
CTACTGAAAAAGCAGGTATAGTAATGACTTCTTTCCCTCTCGTCATGTTCGTCGTGGCACCCTTAAGCGGTATTTTAGCT
GATAGATACGGAGCCCAAATCCTCTCAACTATTGGTGCACTCATTTCTGCAACAGCCCTTTTTCTTATGGTAACTTTAAC
AGAAAAATCTACTATGTTTTCCATTATGACCCATCTTGCCCTTTTTGGCGTAGGAAATGCCATTTTTCAGACACCAAACA
ACAGTGCAGTAATGGGAAGTGCGCCAAAAAACAGATTAGGGGTAGCCTCTGCCTTTCTCGCAACAATGAGAAATGTAGGA
ATGGTAATGGGCATTGCAGTAGGAAGCGCTATATTTACAAACAGGTTAAAAGTCTATCAAGCTCTAAAATTTTCTTCCAA
CACTACCTTTATGATGGCTATTAAAGAAGCTTATATAGCCGCCGGAATCTTTTCATTAATATGCGCCTTTACTTCTCTTG
TGAGAAATGATGTTAAATTAATAAAAGGAAAGGATTGA

Upstream 100 bases:

>100_bases
AGTGCGTGTAAAGAATTAGTAGATAACTTATTTAGCTGACATTTTGCACAGACTTTTGCCAAAGATTGTGGTATAATTTA
TAGTATCGGAGGGAAAATAA

Downstream 100 bases:

>100_bases
TTTAAATGGAGACCACCCTTGCTATAGTAAAACCCGACGGTGTCAAGAGAGGGCTTATAGGAGAAATATTAAAAAGATAT
GAAAACAAAGGTTTAAGGCT

Product: EmrB/QacA family drug resistance transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSQKQYNKWLILSAVVIGSIMGPIDGSIVNIAMPEFTKIFHTNITTVSWVSMTYLLVLSSLMMTFGRLGDMLGYKKLYQY
GLLTFSISSAILSLSVNIYMLIIMRAFQAIGAGMLMSMTSAIITSVFPPNERGKALGINAMSISIGLAIGPTLGGFLLSN
LGWQSIFYINVPIGIIGYIWAHIVVPDNKGVPEKFDIYGSISFFGFLASLLLFISEGGTWGWTSLPSIISLLTSVTFLTI
FVIIENKVDFPMFDFSLLKIRSFTFGNISTLLNFMSQNTMTFLTPFLLQHLGFTTEKAGIVMTSFPLVMFVVAPLSGILA
DRYGAQILSTIGALISATALFLMVTLTEKSTMFSIMTHLALFGVGNAIFQTPNNSAVMGSAPKNRLGVASAFLATMRNVG
MVMGIAVGSAIFTNRLKVYQALKFSSNTTFMMAIKEAYIAAGIFSLICAFTSLVRNDVKLIKGKD

Sequences:

>Translated_465_residues
MSQKQYNKWLILSAVVIGSIMGPIDGSIVNIAMPEFTKIFHTNITTVSWVSMTYLLVLSSLMMTFGRLGDMLGYKKLYQY
GLLTFSISSAILSLSVNIYMLIIMRAFQAIGAGMLMSMTSAIITSVFPPNERGKALGINAMSISIGLAIGPTLGGFLLSN
LGWQSIFYINVPIGIIGYIWAHIVVPDNKGVPEKFDIYGSISFFGFLASLLLFISEGGTWGWTSLPSIISLLTSVTFLTI
FVIIENKVDFPMFDFSLLKIRSFTFGNISTLLNFMSQNTMTFLTPFLLQHLGFTTEKAGIVMTSFPLVMFVVAPLSGILA
DRYGAQILSTIGALISATALFLMVTLTEKSTMFSIMTHLALFGVGNAIFQTPNNSAVMGSAPKNRLGVASAFLATMRNVG
MVMGIAVGSAIFTNRLKVYQALKFSSNTTFMMAIKEAYIAAGIFSLICAFTSLVRNDVKLIKGKD
>Mature_464_residues
SQKQYNKWLILSAVVIGSIMGPIDGSIVNIAMPEFTKIFHTNITTVSWVSMTYLLVLSSLMMTFGRLGDMLGYKKLYQYG
LLTFSISSAILSLSVNIYMLIIMRAFQAIGAGMLMSMTSAIITSVFPPNERGKALGINAMSISIGLAIGPTLGGFLLSNL
GWQSIFYINVPIGIIGYIWAHIVVPDNKGVPEKFDIYGSISFFGFLASLLLFISEGGTWGWTSLPSIISLLTSVTFLTIF
VIIENKVDFPMFDFSLLKIRSFTFGNISTLLNFMSQNTMTFLTPFLLQHLGFTTEKAGIVMTSFPLVMFVVAPLSGILAD
RYGAQILSTIGALISATALFLMVTLTEKSTMFSIMTHLALFGVGNAIFQTPNNSAVMGSAPKNRLGVASAFLATMRNVGM
VMGIAVGSAIFTNRLKVYQALKFSSNTTFMMAIKEAYIAAGIFSLICAFTSLVRNDVKLIKGKD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=400, Percent_Identity=32.75, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1790195, Length=441, Percent_Identity=26.0770975056689, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789042, Length=413, Percent_Identity=25.181598062954, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788710, Length=418, Percent_Identity=25.5980861244019, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788392, Length=306, Percent_Identity=24.8366013071895, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319770, Length=393, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323735, Length=330, Percent_Identity=23.6363636363636, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325455, Length=140, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324954, Length=240, Percent_Identity=27.5, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=28.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=189, Percent_Identity=28.042328042328, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319657, Length=137, Percent_Identity=30.6569343065693, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50573; Mature: 50442

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKQYNKWLILSAVVIGSIMGPIDGSIVNIAMPEFTKIFHTNITTVSWVSMTYLLVLSS
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHH
LMMTFGRLGDMLGYKKLYQYGLLTFSISSAILSLSVNIYMLIIMRAFQAIGAGMLMSMTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIITSVFPPNERGKALGINAMSISIGLAIGPTLGGFLLSNLGWQSIFYINVPIGIIGYIW
HHHHHCCCCCCCCCEEEEEEEEEEEEEEECCHHHHHHHHCCCCCEEEEEECCHHHHHHHH
AHIVVPDNKGVPEKFDIYGSISFFGFLASLLLFISEGGTWGWTSLPSIISLLTSVTFLTI
HEEEECCCCCCCCHHHHEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FVIIENKVDFPMFDFSLLKIRSFTFGNISTLLNFMSQNTMTFLTPFLLQHLGFTTEKAGI
HHHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCE
VMTSFPLVMFVVAPLSGILADRYGAQILSTIGALISATALFLMVTLTEKSTMFSIMTHLA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LFGVGNAIFQTPNNSAVMGSAPKNRLGVASAFLATMRNVGMVMGIAVGSAIFTNRLKVYQ
HHHCCHHHEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKFSSNTTFMMAIKEAYIAAGIFSLICAFTSLVRNDVKLIKGKD
HHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
SQKQYNKWLILSAVVIGSIMGPIDGSIVNIAMPEFTKIFHTNITTVSWVSMTYLLVLSS
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHH
LMMTFGRLGDMLGYKKLYQYGLLTFSISSAILSLSVNIYMLIIMRAFQAIGAGMLMSMTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIITSVFPPNERGKALGINAMSISIGLAIGPTLGGFLLSNLGWQSIFYINVPIGIIGYIW
HHHHHCCCCCCCCCEEEEEEEEEEEEEEECCHHHHHHHHCCCCCEEEEEECCHHHHHHHH
AHIVVPDNKGVPEKFDIYGSISFFGFLASLLLFISEGGTWGWTSLPSIISLLTSVTFLTI
HEEEECCCCCCCCHHHHEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FVIIENKVDFPMFDFSLLKIRSFTFGNISTLLNFMSQNTMTFLTPFLLQHLGFTTEKAGI
HHHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCE
VMTSFPLVMFVVAPLSGILADRYGAQILSTIGALISATALFLMVTLTEKSTMFSIMTHLA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LFGVGNAIFQTPNNSAVMGSAPKNRLGVASAFLATMRNVGMVMGIAVGSAIFTNRLKVYQ
HHHCCHHHEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKFSSNTTFMMAIKEAYIAAGIFSLICAFTSLVRNDVKLIKGKD
HHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]