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The map label for this gene is ccpA [H]

Identifier: 167040826

GI number: 167040826

Start: 2205689

End: 2206699

Strand: Reverse

Name: ccpA [H]

Synonym: Teth514_2203

Alternate gene names: 167040826

Gene position: 2206699-2205689 (Counterclockwise)

Preceding gene: 167040827

Following gene: 167040825

Centisome position: 89.8

GC content: 35.11

Gene sequence:

>1011_bases
ATGGCTGTTACAATAAAAGATATAGCGAAATATGCGGGTGTATCTGTTACAACGGTTTCGAGAGCTTTAAACGGATATCC
GGATGTAAGCGAGGAAACACGTGAAAGAATTAAAAAAATAGCGGAACAACTTAATTATACTCCAAACTCCATTGCAAGAG
GACTTGTCACAAATAAGACCCACACAGTTGGCTTGATTGTTTCTGAATTAATAAAACCTGGGGCGTATCATCCTTTCTTC
CTCGAAGTGCTTGCAGGTATAAAAGCAGGATTAAAAAAAGATAAATATGACCTTATACTTTTTACTGTAGACCCGGAAAG
CCAAGATGCCACTTCCTATGAGAAGCTTTGCAATGACAGAAAAGTGGAAGGGGCTATTGTAGAAGGTTTAAGATTGAGTG
ATCCTTATATTGAAGAAATAAAGAGAACACAAATTCCCACTGTTCTGATTGATATACCGATACTGACTGATAAAGTGGGA
TATGTAAGTTCGGATAACGTTCAGGCGGCTTTTGAAGCTACAAGTTATCTTATAAAGTTAGGACATAGAAATATTGGATT
TATAAATGGGCATAATGATGCGGCTGTAAGCTTTGAAAGGTTAGAAGGTTATAAAAAAGCTCTTGAAAAAAATAATATAC
CTTACAAAGAGGAATATGTAGTTTTTGATGATTTTACTCAAGAAGGTGGATATAATTCTTTTAAGACGTTAGTTTTTGAA
CATCCGGAAATAACTGCTGTTTTCCATGCTTCTGATTTGATGGCAATAGGGTCTTTCAAAGCAGCAAAAGACTTAGGAAT
GAAAGTGCCTGATGACATCTCTATTGTAGGTTTTGACGATATTGAACTTGCATCCCTTATTACTCCTGGACTTACTACTA
TAAGACAAGATACTTTTAAGATGGGATATAATGCAGCAAAACATCTTTTATCTATTATAAAAGGGGAAAAGCCTCAGCAT
ATATTAATACCTCATAAGCTTGTAATTAGAGATTCAGCTAGAAAGATATAA

Upstream 100 bases:

>100_bases
AGTGTGTCCTTACGGAAGGAAAAAATCTGTTGACAGGTTAAAAGGTTTTTGATAAAATGAAATCAAACAACCAAAACGTT
TTGGAAAAGGTGGATATTAA

Downstream 100 bases:

>100_bases
TTTTTTTTAAAAAGTACCCAAAACGTTTCGGATAAAATTTTTAGCAGGAATCAGGAGGTATATAAGTGGTAAAGCACATG
TTTTTAGAGGATGTAAACAA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRERIKKIAEQLNYTPNSIARGLVTNKTHTVGLIVSELIKPGAYHPFF
LEVLAGIKAGLKKDKYDLILFTVDPESQDATSYEKLCNDRKVEGAIVEGLRLSDPYIEEIKRTQIPTVLIDIPILTDKVG
YVSSDNVQAAFEATSYLIKLGHRNIGFINGHNDAAVSFERLEGYKKALEKNNIPYKEEYVVFDDFTQEGGYNSFKTLVFE
HPEITAVFHASDLMAIGSFKAAKDLGMKVPDDISIVGFDDIELASLITPGLTTIRQDTFKMGYNAAKHLLSIIKGEKPQH
ILIPHKLVIRDSARKI

Sequences:

>Translated_336_residues
MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRERIKKIAEQLNYTPNSIARGLVTNKTHTVGLIVSELIKPGAYHPFF
LEVLAGIKAGLKKDKYDLILFTVDPESQDATSYEKLCNDRKVEGAIVEGLRLSDPYIEEIKRTQIPTVLIDIPILTDKVG
YVSSDNVQAAFEATSYLIKLGHRNIGFINGHNDAAVSFERLEGYKKALEKNNIPYKEEYVVFDDFTQEGGYNSFKTLVFE
HPEITAVFHASDLMAIGSFKAAKDLGMKVPDDISIVGFDDIELASLITPGLTTIRQDTFKMGYNAAKHLLSIIKGEKPQH
ILIPHKLVIRDSARKI
>Mature_335_residues
AVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRERIKKIAEQLNYTPNSIARGLVTNKTHTVGLIVSELIKPGAYHPFFL
EVLAGIKAGLKKDKYDLILFTVDPESQDATSYEKLCNDRKVEGAIVEGLRLSDPYIEEIKRTQIPTVLIDIPILTDKVGY
VSSDNVQAAFEATSYLIKLGHRNIGFINGHNDAAVSFERLEGYKKALEKNNIPYKEEYVVFDDFTQEGGYNSFKTLVFEH
PEITAVFHASDLMAIGSFKAAKDLGMKVPDDISIVGFDDIELASLITPGLTTIRQDTFKMGYNAAKHLLSIIKGEKPQHI
LIPHKLVIRDSARKI

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=341, Percent_Identity=35.1906158357771, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=32.7327327327327, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1790194, Length=300, Percent_Identity=32, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=29.8192771084337, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=30.976430976431, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789202, Length=302, Percent_Identity=30.794701986755, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788474, Length=345, Percent_Identity=30.4347826086957, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=30.4733727810651, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=26.3313609467456, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=27.355623100304, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=27.9874213836478, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789456, Length=355, Percent_Identity=26.7605633802817, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790689, Length=335, Percent_Identity=25.6716417910448, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786268, Length=306, Percent_Identity=23.8562091503268, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790192, Length=276, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37334; Mature: 37203

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRERIKKIAEQLNYTPNSIARGLVTNKT
CEEEHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
HTVGLIVSELIKPGAYHPFFLEVLAGIKAGLKKDKYDLILFTVDPESQDATSYEKLCNDR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHCCC
KVEGAIVEGLRLSDPYIEEIKRTQIPTVLIDIPILTDKVGYVSSDNVQAAFEATSYLIKL
CCCHHHHCCCCCCCHHHHHHHHHCCCEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHH
GHRNIGFINGHNDAAVSFERLEGYKKALEKNNIPYKEEYVVFDDFTQEGGYNSFKTLVFE
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHEEEE
HPEITAVFHASDLMAIGSFKAAKDLGMKVPDDISIVGFDDIELASLITPGLTTIRQDTFK
CCCEEEEEECCCHHHHCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHH
MGYNAAKHLLSIIKGEKPQHILIPHKLVIRDSARKI
HHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCC
>Mature Secondary Structure 
AVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRERIKKIAEQLNYTPNSIARGLVTNKT
EEEHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
HTVGLIVSELIKPGAYHPFFLEVLAGIKAGLKKDKYDLILFTVDPESQDATSYEKLCNDR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHCCC
KVEGAIVEGLRLSDPYIEEIKRTQIPTVLIDIPILTDKVGYVSSDNVQAAFEATSYLIKL
CCCHHHHCCCCCCCHHHHHHHHHCCCEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHH
GHRNIGFINGHNDAAVSFERLEGYKKALEKNNIPYKEEYVVFDDFTQEGGYNSFKTLVFE
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHEEEE
HPEITAVFHASDLMAIGSFKAAKDLGMKVPDDISIVGFDDIELASLITPGLTTIRQDTFK
CCCEEEEEECCCHHHHCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHH
MGYNAAKHLLSIIKGEKPQHILIPHKLVIRDSARKI
HHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]