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The map label for this gene is glnA [H]

Identifier: 167040801

GI number: 167040801

Start: 2176549

End: 2177883

Strand: Reverse

Name: glnA [H]

Synonym: Teth514_2178

Alternate gene names: 167040801

Gene position: 2177883-2176549 (Counterclockwise)

Preceding gene: 167040802

Following gene: 167040800

Centisome position: 88.63

GC content: 36.93

Gene sequence:

>1335_bases
ATGGGTAAAAAATATAGCAAAGAAGATGTTTTAAGACTGGCAAAAGAGAATGGGGTAGAATATGTACATCTTCAATTTAG
CGACATCTTTGGGGTTATGAAAAATGTCTCTATTCCTGTGGAAGAATTAAGTAAGGCTCTTAACAATGAAATCATGTTTG
ACGGATCTTCAATTGACGGATTTGTGAGAATTGAAGAATCAGACATGTATTTAAGGCCGGACCCTGATACGTTTGTGATC
TTCCCGTGGAGGACAAACTCTGGGGTAGAGGCAAGACTCATATGTGATATTTACAATTACGATGGAACTCCCTTTGAAGG
AGACCCTCGCTATGTTTTAAAAAGAAATTTAGAAGAGGCAAAGAAATTAGGTTATCAATTTAATGTAGGGCCTGAATGCG
AGTTTTATCTCTTTTTGACGGATGAAAAAGGTAATCTTACGACAATAACTCAAGACGATGCAAGTTATTTTGACATGGCA
CCTGTGGACTTAGGGGAAAGCGCAAGAAAAGAAATGGTGTCGACTCTTAAGCAACTAGGGTTTCAAATTGAAGCATCTCA
TCACGAAGTGGGACCAGGACAACATGAGATAGATTTCAAATATGACGATGCATTAACTACTGCTGACAATGTGATGACTT
TTAAAATGGTGGTAAGGATAATTGCTCAAAAACATGGATTGCACGCTACCTTTATGCCGAAACCAGTTTTTGGAATTGCG
GGGTCTGGAATGCATATGAACATGTCACTTACAAAAGATGGTAAAAATGCTTTTTATGACCCTTCTGACCCTCTAGGGTT
AAGTAATGTATGTTATAACTATATAGGAGGAATTATAAAACATGCAAAAGCTATGACAGCTATTACTAACCCTATTGTTA
ATTCTTATAAACGGCTAGTTTCAGGCTATGAAGCTCCTGTAAATATTGCTTGGTCTTTACGGAACAGAAGTCCTTTAATA
CGAATTCCTGCCAAAAGAGGGGAATCTACAAGGATAGAGCTTAGAAGTCCTGATCCAAGTAGCAATCCTTATCTTGCTTT
GGCTGTTGCATTGGCAGCAGGATTAGATGGCATAAAGAATAATATAACACCGCCACCACCTGTAAATGCAAATATATACC
ATATGAATAAAGAAGAATTAGAAAACTTAGGAATTGAAAGACTGCCAGGCTCTTTAGAAGAAGCTTTAAACGAGTTAGAA
AAGGATGAAGTTATAAAAGAAGCATTAGGCGATCATGTGTATACAAAATTTTTGGAGGCTAAAAGAGCAGAATGGGATGA
GTACAAAATATACGTTACTCAGTGGGAATTAGATCAATATCTTTCTAAATTCTAA

Upstream 100 bases:

>100_bases
TAAAATTTAATAATAATTTATAGGGAAGGCAAGGGCGTCTTCAAATGGGGTGGTGGTATCCTATTTGAGTGCGCCCTTAA
TTTATTAAAGGAGGAATATT

Downstream 100 bases:

>100_bases
GTTAATTAGAGGTGTCTCGATGAGCCAATGGCGAATTGTTTTGGCAGACAGCAGTGATTTGTCTCGGCAGTTCATAAAGA
ATGTGTTATTAGCGAATGGA

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MGKKYSKEDVLRLAKENGVEYVHLQFSDIFGVMKNVSIPVEELSKALNNEIMFDGSSIDGFVRIEESDMYLRPDPDTFVI
FPWRTNSGVEARLICDIYNYDGTPFEGDPRYVLKRNLEEAKKLGYQFNVGPECEFYLFLTDEKGNLTTITQDDASYFDMA
PVDLGESARKEMVSTLKQLGFQIEASHHEVGPGQHEIDFKYDDALTTADNVMTFKMVVRIIAQKHGLHATFMPKPVFGIA
GSGMHMNMSLTKDGKNAFYDPSDPLGLSNVCYNYIGGIIKHAKAMTAITNPIVNSYKRLVSGYEAPVNIAWSLRNRSPLI
RIPAKRGESTRIELRSPDPSSNPYLALAVALAAGLDGIKNNITPPPPVNANIYHMNKEELENLGIERLPGSLEEALNELE
KDEVIKEALGDHVYTKFLEAKRAEWDEYKIYVTQWELDQYLSKF

Sequences:

>Translated_444_residues
MGKKYSKEDVLRLAKENGVEYVHLQFSDIFGVMKNVSIPVEELSKALNNEIMFDGSSIDGFVRIEESDMYLRPDPDTFVI
FPWRTNSGVEARLICDIYNYDGTPFEGDPRYVLKRNLEEAKKLGYQFNVGPECEFYLFLTDEKGNLTTITQDDASYFDMA
PVDLGESARKEMVSTLKQLGFQIEASHHEVGPGQHEIDFKYDDALTTADNVMTFKMVVRIIAQKHGLHATFMPKPVFGIA
GSGMHMNMSLTKDGKNAFYDPSDPLGLSNVCYNYIGGIIKHAKAMTAITNPIVNSYKRLVSGYEAPVNIAWSLRNRSPLI
RIPAKRGESTRIELRSPDPSSNPYLALAVALAAGLDGIKNNITPPPPVNANIYHMNKEELENLGIERLPGSLEEALNELE
KDEVIKEALGDHVYTKFLEAKRAEWDEYKIYVTQWELDQYLSKF
>Mature_443_residues
GKKYSKEDVLRLAKENGVEYVHLQFSDIFGVMKNVSIPVEELSKALNNEIMFDGSSIDGFVRIEESDMYLRPDPDTFVIF
PWRTNSGVEARLICDIYNYDGTPFEGDPRYVLKRNLEEAKKLGYQFNVGPECEFYLFLTDEKGNLTTITQDDASYFDMAP
VDLGESARKEMVSTLKQLGFQIEASHHEVGPGQHEIDFKYDDALTTADNVMTFKMVVRIIAQKHGLHATFMPKPVFGIAG
SGMHMNMSLTKDGKNAFYDPSDPLGLSNVCYNYIGGIIKHAKAMTAITNPIVNSYKRLVSGYEAPVNIAWSLRNRSPLIR
IPAKRGESTRIELRSPDPSSNPYLALAVALAAGLDGIKNNITPPPPVNANIYHMNKEELENLGIERLPGSLEEALNELEK
DEVIKEALGDHVYTKFLEAKRAEWDEYKIYVTQWELDQYLSKF

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=443, Percent_Identity=25.0564334085779, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1790301, Length=473, Percent_Identity=41.014799154334, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI87081870, Length=474, Percent_Identity=26.5822784810127, Blast_Score=149, Evalue=5e-37,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50108; Mature: 49977

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKYSKEDVLRLAKENGVEYVHLQFSDIFGVMKNVSIPVEELSKALNNEIMFDGSSIDG
CCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCE
FVRIEESDMYLRPDPDTFVIFPWRTNSGVEARLICDIYNYDGTPFEGDPRYVLKRNLEEA
EEEEECCCEEECCCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHHCCHHHH
KKLGYQFNVGPECEFYLFLTDEKGNLTTITQDDASYFDMAPVDLGESARKEMVSTLKQLG
HHCCEEECCCCCEEEEEEEECCCCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCC
FQIEASHHEVGPGQHEIDFKYDDALTTADNVMTFKMVVRIIAQKHGLHATFMPKPVFGIA
EEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEC
GSGMHMNMSLTKDGKNAFYDPSDPLGLSNVCYNYIGGIIKHAKAMTAITNPIVNSYKRLV
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGYEAPVNIAWSLRNRSPLIRIPAKRGESTRIELRSPDPSSNPYLALAVALAAGLDGIKN
CCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
NITPPPPVNANIYHMNKEELENLGIERLPGSLEEALNELEKDEVIKEALGDHVYTKFLEA
CCCCCCCCCCEEEECCHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRAEWDEYKIYVTQWELDQYLSKF
HCCCCCEEEEEEEEECHHHHHHCC
>Mature Secondary Structure 
GKKYSKEDVLRLAKENGVEYVHLQFSDIFGVMKNVSIPVEELSKALNNEIMFDGSSIDG
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCE
FVRIEESDMYLRPDPDTFVIFPWRTNSGVEARLICDIYNYDGTPFEGDPRYVLKRNLEEA
EEEEECCCEEECCCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHHCCHHHH
KKLGYQFNVGPECEFYLFLTDEKGNLTTITQDDASYFDMAPVDLGESARKEMVSTLKQLG
HHCCEEECCCCCEEEEEEEECCCCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCC
FQIEASHHEVGPGQHEIDFKYDDALTTADNVMTFKMVVRIIAQKHGLHATFMPKPVFGIA
EEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEC
GSGMHMNMSLTKDGKNAFYDPSDPLGLSNVCYNYIGGIIKHAKAMTAITNPIVNSYKRLV
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGYEAPVNIAWSLRNRSPLIRIPAKRGESTRIELRSPDPSSNPYLALAVALAAGLDGIKN
CCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
NITPPPPVNANIYHMNKEELENLGIERLPGSLEEALNELEKDEVIKEALGDHVYTKFLEA
CCCCCCCCCCEEEECCHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRAEWDEYKIYVTQWELDQYLSKF
HCCCCCEEEEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2891680; 1981087 [H]