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The map label for this gene is ydfD [H]

Identifier: 167040798

GI number: 167040798

Start: 2173194

End: 2174627

Strand: Reverse

Name: ydfD [H]

Synonym: Teth514_2175

Alternate gene names: 167040798

Gene position: 2174627-2173194 (Counterclockwise)

Preceding gene: 167040800

Following gene: 167040795

Centisome position: 88.5

GC content: 30.47

Gene sequence:

>1434_bases
ATGAATAAAATAACAATTGATAAAAATAAAAATGTGCCTTTATATATTCAATTGTACAGTCAAATAAAAAGATTTATAGA
GAATGGCAGCCTGCCAGGTGGATATAAACTCCCCACTATAAGAAGCCTTGCAAAGGAGTTGGGGGTAAACAATATTACAG
TGATTAATGCTTATAAGCTTTTAGAGCAAAATGGATATATATATACTAAAGTAGGAAGTGGTACTTACGTTTGTGAAGAT
ATAAAAAAAGAAGAGGACCTTGATGAAAGCTTTAAATTAACAGACCAAGGAGAAATTCCCTTAAAGAAAGGAATTATAAA
TTTTGCTTCTTCATCTCTTAATCCAGAGCTTTTTCCAGTGGAGGATTTTGGAGATTTAATCAATAGAGTATTGAGAAGAG
ATGGAGGATATGCTTTTGAGTATCAAGACACAAGAGGATATAAACCATTAAGAGAATCTATAAAAGAATTTGTAAAGAAA
GATGAAATATTTACTTATGTTGAAAATATACAGGTAATTTCTGGGGGACAGCAAGGTATAGATGTAGTATCGAAAGCGCT
AATAAATTTTGAAGATAGCATAATTGTTGAAAGACCCACCTATTCGTGGGCTTTAGCCTCTTTTGAATCGAGAGGAGCAG
AGATTTTAGAAGTGGATTTAAAAAAAGATGGAATAAATTTAGAGGAATTGGAGGATAAGTTAAAGAAATTTAAGCCAAAG
TTCATATATACAATACCCAATTTTCACAATCCCACCGGCATTGTTTACAGTGAGGAAAAAAAGAAGAAACTAATAGAGTT
GGCGGAAAAATATGAAACTTATATTTTAGAAGATGATTTTGCCAGTGATTTAAGTTTTACTGAAGAAAAGATATTGCCAC
TTAAAGCTTATGATAAATATGACAGAGTCATTTATATAAAAAGCTTCTCAAAAATATACATGCCGGGTTTGAGGTTAGGT
TTTATAATTGCTCCAGAAAGGCTAGTAAGTAGTTTCCTAAAAGCCAAATATGTGACAGATTTATCTACTTCAGGTTTGAT
GCAAAGAGCCTTTGATTTATATCTTAGAGAAAATATTTGGAAAAATCATATTGAAGAAATAAAACAAGTAATGAAAAAAA
GATTTGAAAAGATGGGTAATGGACTTCAGATGTTAAAAAATTATGTAGAATTTGAATATCCTAAAGGGGGTTTTTACTAC
TGGTTAAGACTTAAAGACAATATTTCTGCTAAAAATTTATATTCTAAATGTTTAGAGAAAAATTTACTTATAGTCCCAGG
AGACATGTTTTTTGCAATAAAAAAAGAGACCAATTTTATAAGATTAAGTTTTGCCTCTTGTGAGTTGGAGGAGATAGATA
AGGGGATAGATATACTGAAAGAGGTTTTAGAAGGAGAATCTAATGAAAACGGCATATATCTTCCTATAATATAA

Upstream 100 bases:

>100_bases
TTTCTTCCATATCCATTATAATATATTTTAAAATTAAAAAGAATTTTTGTCATGATAATGGTATAATAATTGTAGCGATA
CAATTTTGCGAGGGATGGAT

Downstream 100 bases:

>100_bases
AAAGGCCGTAAGATGGCCTTTTTAGACTGTAGACAAACTTTCGTAAAGGAGATATTTTGCATAAGGAGCGACTTGTTACA
AAGCGGCAACAAAACTTAGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MNKITIDKNKNVPLYIQLYSQIKRFIENGSLPGGYKLPTIRSLAKELGVNNITVINAYKLLEQNGYIYTKVGSGTYVCED
IKKEEDLDESFKLTDQGEIPLKKGIINFASSSLNPELFPVEDFGDLINRVLRRDGGYAFEYQDTRGYKPLRESIKEFVKK
DEIFTYVENIQVISGGQQGIDVVSKALINFEDSIIVERPTYSWALASFESRGAEILEVDLKKDGINLEELEDKLKKFKPK
FIYTIPNFHNPTGIVYSEEKKKKLIELAEKYETYILEDDFASDLSFTEEKILPLKAYDKYDRVIYIKSFSKIYMPGLRLG
FIIAPERLVSSFLKAKYVTDLSTSGLMQRAFDLYLRENIWKNHIEEIKQVMKKRFEKMGNGLQMLKNYVEFEYPKGGFYY
WLRLKDNISAKNLYSKCLEKNLLIVPGDMFFAIKKETNFIRLSFASCELEEIDKGIDILKEVLEGESNENGIYLPII

Sequences:

>Translated_477_residues
MNKITIDKNKNVPLYIQLYSQIKRFIENGSLPGGYKLPTIRSLAKELGVNNITVINAYKLLEQNGYIYTKVGSGTYVCED
IKKEEDLDESFKLTDQGEIPLKKGIINFASSSLNPELFPVEDFGDLINRVLRRDGGYAFEYQDTRGYKPLRESIKEFVKK
DEIFTYVENIQVISGGQQGIDVVSKALINFEDSIIVERPTYSWALASFESRGAEILEVDLKKDGINLEELEDKLKKFKPK
FIYTIPNFHNPTGIVYSEEKKKKLIELAEKYETYILEDDFASDLSFTEEKILPLKAYDKYDRVIYIKSFSKIYMPGLRLG
FIIAPERLVSSFLKAKYVTDLSTSGLMQRAFDLYLRENIWKNHIEEIKQVMKKRFEKMGNGLQMLKNYVEFEYPKGGFYY
WLRLKDNISAKNLYSKCLEKNLLIVPGDMFFAIKKETNFIRLSFASCELEEIDKGIDILKEVLEGESNENGIYLPII
>Mature_477_residues
MNKITIDKNKNVPLYIQLYSQIKRFIENGSLPGGYKLPTIRSLAKELGVNNITVINAYKLLEQNGYIYTKVGSGTYVCED
IKKEEDLDESFKLTDQGEIPLKKGIINFASSSLNPELFPVEDFGDLINRVLRRDGGYAFEYQDTRGYKPLRESIKEFVKK
DEIFTYVENIQVISGGQQGIDVVSKALINFEDSIIVERPTYSWALASFESRGAEILEVDLKKDGINLEELEDKLKKFKPK
FIYTIPNFHNPTGIVYSEEKKKKLIELAEKYETYILEDDFASDLSFTEEKILPLKAYDKYDRVIYIKSFSKIYMPGLRLG
FIIAPERLVSSFLKAKYVTDLSTSGLMQRAFDLYLRENIWKNHIEEIKQVMKKRFEKMGNGLQMLKNYVEFEYPKGGFYY
WLRLKDNISAKNLYSKCLEKNLLIVPGDMFFAIKKETNFIRLSFASCELEEIDKGIDILKEVLEGESNENGIYLPII

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=399, Percent_Identity=27.5689223057644, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI33469970, Length=399, Percent_Identity=27.5689223057644, Blast_Score=146, Evalue=5e-35,
Organism=Escherichia coli, GI1787710, Length=444, Percent_Identity=27.9279279279279, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1790797, Length=455, Percent_Identity=25.0549450549451, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788722, Length=300, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI48994949, Length=232, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=292, Percent_Identity=26.7123287671233, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=391, Percent_Identity=23.2736572890026, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321929, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321000, Length=256, Percent_Identity=26.171875, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356535, Length=374, Percent_Identity=27.5401069518717, Blast_Score=125, Evalue=8e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55216; Mature: 55216

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKITIDKNKNVPLYIQLYSQIKRFIENGSLPGGYKLPTIRSLAKELGVNNITVINAYKL
CCCEEECCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHH
LEQNGYIYTKVGSGTYVCEDIKKEEDLDESFKLTDQGEIPLKKGIINFASSSLNPELFPV
HHCCCEEEEEECCCCEEEHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEH
EDFGDLINRVLRRDGGYAFEYQDTRGYKPLRESIKEFVKKDEIFTYVENIQVISGGQQGI
HHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHH
DVVSKALINFEDSIIVERPTYSWALASFESRGAEILEVDLKKDGINLEELEDKLKKFKPK
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
FIYTIPNFHNPTGIVYSEEKKKKLIELAEKYETYILEDDFASDLSFTEEKILPLKAYDKY
EEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCCCHHCCCC
DRVIYIKSFSKIYMPGLRLGFIIAPERLVSSFLKAKYVTDLSTSGLMQRAFDLYLRENIW
CCEEEEECCHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KNHIEEIKQVMKKRFEKMGNGLQMLKNYVEFEYPKGGFYYWLRLKDNISAKNLYSKCLEK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCEEEEEEEECCCCHHHHHHHHHHC
NLLIVPGDMFFAIKKETNFIRLSFASCELEEIDKGIDILKEVLEGESNENGIYLPII
CEEEECCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MNKITIDKNKNVPLYIQLYSQIKRFIENGSLPGGYKLPTIRSLAKELGVNNITVINAYKL
CCCEEECCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHH
LEQNGYIYTKVGSGTYVCEDIKKEEDLDESFKLTDQGEIPLKKGIINFASSSLNPELFPV
HHCCCEEEEEECCCCEEEHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEH
EDFGDLINRVLRRDGGYAFEYQDTRGYKPLRESIKEFVKKDEIFTYVENIQVISGGQQGI
HHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHH
DVVSKALINFEDSIIVERPTYSWALASFESRGAEILEVDLKKDGINLEELEDKLKKFKPK
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
FIYTIPNFHNPTGIVYSEEKKKKLIELAEKYETYILEDDFASDLSFTEEKILPLKAYDKY
EEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCCCHHCCCC
DRVIYIKSFSKIYMPGLRLGFIIAPERLVSSFLKAKYVTDLSTSGLMQRAFDLYLRENIW
CCEEEEECCHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KNHIEEIKQVMKKRFEKMGNGLQMLKNYVEFEYPKGGFYYWLRLKDNISAKNLYSKCLEK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCEEEEEEEECCCCHHHHHHHHHHC
NLLIVPGDMFFAIKKETNFIRLSFASCELEEIDKGIDILKEVLEGESNENGIYLPII
CEEEECCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]