| Definition | Thermoanaerobacter sp. X514 chromosome, complete genome. |
|---|---|
| Accession | NC_010320 |
| Length | 2,457,259 |
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The map label for this gene is mrdA [H]
Identifier: 167040754
GI number: 167040754
Start: 2135400
End: 2137685
Strand: Reverse
Name: mrdA [H]
Synonym: Teth514_2131
Alternate gene names: 167040754
Gene position: 2137685-2135400 (Counterclockwise)
Preceding gene: 167040755
Following gene: 167040753
Centisome position: 86.99
GC content: 34.25
Gene sequence:
>2286_bases TTGAATGAGAGCCTTAAAAAAAAGTTTTATACTTTTGGAGCCATTATCCTTGTTCTTCTTGTCGTTTTAGTTTCCCGCTT AATCTATTTACAGCTGATAAAGGGCGACTATTATAGAGAAATATCAATGCGCCAAGCAATTAGACGTATACCTATTGAGG CTCCTCGTGGAGAAATTGTTGATAGGTATGGAGTAAAATTAGCCACAAATAGACCAAGCTTTTCTGTAGATATTATAAAA GGAGAAGTGGTTGATAGTCATCTTAACGAGACTATATTAAAATTAATGAATATTTTGACGAAAAATAATGTAAAATATAA AGACGATTTGCCTATCTATTTAGATGAAAATGGAAATCCTTATTTCAATTTTAAAAATTCAGATGAAGTATCAGTAAAAG AAGAAACTTTAAAAGCTCGAGAAAAAGCCTGGAAAAAAGCTAATAACATACATGAAAATGCTACTGCTAAAGAGGCATGG GATATTTTAATAAAAAAATTTAAAATACCTAAGGATATGGATCCAATAGAAGCAAGAAAAATAATGGTTGTACGTCAATT AATGGAAGAACAAGGATATAATCAATATCAGCCAGTAGAAATAGCTGTGGACGTGGACCAAAAAACGATTGCTGAGATTG AGGAAAATCATTTAGAATTGCCAGGAATTATGATAAATGTAAAGCCTGTTAGATATTATCCTTATGAAACACTATTATCC CAAACTTTAGGATATATTGGTCGAATTACTCAAGAAGATTTAAAAAACTTGGATATGAGTAAATACAAACTTACAGATTT GGTTGGGCGTTCTGGCCTTGAAGCATTGTATGAAAAGTATTTAAGGGGGAAAGATGGTGGACAACAAGTAGTAGTAGATA ATTATGGAAGATTAATAAAGAATTTAGGGACAGAACCTCCTGTACCAGGTGACACTATATTTTTAACCATTGACAAAAAT ATTCAAGAGGCGGCAGAACAATCTCTTATCACAACTATGCAAAATATAAGAGAGGGGAAATATGGCGAGTCATTTCCTGC TAATATTGGAGCAGCAGTGGTTGTAGATGTACACACAGGTAAAGTTTTAGCATTAGCCAATATCCCGGGTTATGATCCAA ACATTTTTGCCACTGGCAATCCTCCTAAAGATGTAGTAAATGAACTTTTTAAATCAAGAGATGCTACTGTTGATCCAAGT CCTATTTTCAATTATGCAACTCAAGGAGCAGTACCTCCAGGATCTACCTTCAAGATGGCTGTTGCATTCGCAGCTTTAGA CACGGGTGTCACAACGGTTGATGAAAAATATTTAGACCCAGGAATATATCCTTATACAGGACAACGTAACTGGGCGTGGC CACGGACACAAGGTTGGGTAAATGTTTCTGATGCAATTAAATATTCTACTAATACCTATTTTTTTGAAATGGGAAGAAGA ATGGGAATAGATAAAATAGTCGAATATGCCAAGAAATTTGGTTTAGACCAAAAAACAGGAATAGAACTGTATGAAGCAAA AGGTGTTATTGCAAGTCCACAATATAAAAGAGAATATTATCTTGGGTTGATAAAATCAATGGTGAAAACAGATACAAATC CAGATGGAGTTATAACGGAAGAACAGTATCAAAAAATTGTAGAAATCATTGATAAAGGGAATTTGAGTGACTATAATACC TTTTTACAATTAGAAAAGATGGGTATAAAAGATACAAAGCTTCAAAAGAAGATATGGGAAATGATGTATTATGCAAAACA TTGGAGCTTGACAAATACTTGTAGTGCGGCAATAGGTCAAGGTGATAATCAGTTTACTCCTTTACAAATTGCCAGTTATG TGTCTACATTAATAAATGGGGGGATTAGATATAGACTTCATTTAGTTGATAAAATTATATCCCCCGAAGGAAAAATTGTT GAAGAAACAAAACCAGAAGTTTTAGATAGAATTCATATTTCCAAGGAATACCTCGATGCTATAAAGTTAGGTATGAAAGG AGTAACCGAAAGAGGAGGTACTGCAAGCGGTGCTTTTCACAATTTCCCTATTCCTGTAGGAGGCAAGACAGGTACTGCAG AAGCAGTTAGAAGGGCTAATTATGCTTGGTTTGTTGGTTTTGCCCCTTATGATGATCCTCAAATAGTTGTAGTTGTGGTT ATATACCAAGGAGGACATGGTTCTTACGCAGGTTATGTAGCGAGAGATATTTTTGATGCTTATTTTGGACTGAGTAAAAA TAATACAGGTGAAACCTTCAATGTGATAAATTTGCCTATAAGATGA
Upstream 100 bases:
>100_bases TTACTGCTTTTGCCTATAGATATTTAGTTTCCTTTAACAGATATGTTAATGAAAATAAAGTAAATCTTTTTAGAAAAAGC AAATTTTGAAGGTGATATCA
Downstream 100 bases:
>100_bases TTTTGGGGTGAGGATGTTTTATCCTCTTTTTTTCTTTAACAAGAAGGAAAATTACGATTTATGGAGAATATAGATAATAA CGAGGGTTTTACGGAGGTAG
Product: penicillin-binding protein, transpeptidase
Products: NA
Alternate protein names: PBP-2 [H]
Number of amino acids: Translated: 761; Mature: 761
Protein sequence:
>761_residues MNESLKKKFYTFGAIILVLLVVLVSRLIYLQLIKGDYYREISMRQAIRRIPIEAPRGEIVDRYGVKLATNRPSFSVDIIK GEVVDSHLNETILKLMNILTKNNVKYKDDLPIYLDENGNPYFNFKNSDEVSVKEETLKAREKAWKKANNIHENATAKEAW DILIKKFKIPKDMDPIEARKIMVVRQLMEEQGYNQYQPVEIAVDVDQKTIAEIEENHLELPGIMINVKPVRYYPYETLLS QTLGYIGRITQEDLKNLDMSKYKLTDLVGRSGLEALYEKYLRGKDGGQQVVVDNYGRLIKNLGTEPPVPGDTIFLTIDKN IQEAAEQSLITTMQNIREGKYGESFPANIGAAVVVDVHTGKVLALANIPGYDPNIFATGNPPKDVVNELFKSRDATVDPS PIFNYATQGAVPPGSTFKMAVAFAALDTGVTTVDEKYLDPGIYPYTGQRNWAWPRTQGWVNVSDAIKYSTNTYFFEMGRR MGIDKIVEYAKKFGLDQKTGIELYEAKGVIASPQYKREYYLGLIKSMVKTDTNPDGVITEEQYQKIVEIIDKGNLSDYNT FLQLEKMGIKDTKLQKKIWEMMYYAKHWSLTNTCSAAIGQGDNQFTPLQIASYVSTLINGGIRYRLHLVDKIISPEGKIV EETKPEVLDRIHISKEYLDAIKLGMKGVTERGGTASGAFHNFPIPVGGKTGTAEAVRRANYAWFVGFAPYDDPQIVVVVV IYQGGHGSYAGYVARDIFDAYFGLSKNNTGETFNVINLPIR
Sequences:
>Translated_761_residues MNESLKKKFYTFGAIILVLLVVLVSRLIYLQLIKGDYYREISMRQAIRRIPIEAPRGEIVDRYGVKLATNRPSFSVDIIK GEVVDSHLNETILKLMNILTKNNVKYKDDLPIYLDENGNPYFNFKNSDEVSVKEETLKAREKAWKKANNIHENATAKEAW DILIKKFKIPKDMDPIEARKIMVVRQLMEEQGYNQYQPVEIAVDVDQKTIAEIEENHLELPGIMINVKPVRYYPYETLLS QTLGYIGRITQEDLKNLDMSKYKLTDLVGRSGLEALYEKYLRGKDGGQQVVVDNYGRLIKNLGTEPPVPGDTIFLTIDKN IQEAAEQSLITTMQNIREGKYGESFPANIGAAVVVDVHTGKVLALANIPGYDPNIFATGNPPKDVVNELFKSRDATVDPS PIFNYATQGAVPPGSTFKMAVAFAALDTGVTTVDEKYLDPGIYPYTGQRNWAWPRTQGWVNVSDAIKYSTNTYFFEMGRR MGIDKIVEYAKKFGLDQKTGIELYEAKGVIASPQYKREYYLGLIKSMVKTDTNPDGVITEEQYQKIVEIIDKGNLSDYNT FLQLEKMGIKDTKLQKKIWEMMYYAKHWSLTNTCSAAIGQGDNQFTPLQIASYVSTLINGGIRYRLHLVDKIISPEGKIV EETKPEVLDRIHISKEYLDAIKLGMKGVTERGGTASGAFHNFPIPVGGKTGTAEAVRRANYAWFVGFAPYDDPQIVVVVV IYQGGHGSYAGYVARDIFDAYFGLSKNNTGETFNVINLPIR >Mature_761_residues MNESLKKKFYTFGAIILVLLVVLVSRLIYLQLIKGDYYREISMRQAIRRIPIEAPRGEIVDRYGVKLATNRPSFSVDIIK GEVVDSHLNETILKLMNILTKNNVKYKDDLPIYLDENGNPYFNFKNSDEVSVKEETLKAREKAWKKANNIHENATAKEAW DILIKKFKIPKDMDPIEARKIMVVRQLMEEQGYNQYQPVEIAVDVDQKTIAEIEENHLELPGIMINVKPVRYYPYETLLS QTLGYIGRITQEDLKNLDMSKYKLTDLVGRSGLEALYEKYLRGKDGGQQVVVDNYGRLIKNLGTEPPVPGDTIFLTIDKN IQEAAEQSLITTMQNIREGKYGESFPANIGAAVVVDVHTGKVLALANIPGYDPNIFATGNPPKDVVNELFKSRDATVDPS PIFNYATQGAVPPGSTFKMAVAFAALDTGVTTVDEKYLDPGIYPYTGQRNWAWPRTQGWVNVSDAIKYSTNTYFFEMGRR MGIDKIVEYAKKFGLDQKTGIELYEAKGVIASPQYKREYYLGLIKSMVKTDTNPDGVITEEQYQKIVEIIDKGNLSDYNT FLQLEKMGIKDTKLQKKIWEMMYYAKHWSLTNTCSAAIGQGDNQFTPLQIASYVSTLINGGIRYRLHLVDKIISPEGKIV EETKPEVLDRIHISKEYLDAIKLGMKGVTERGGTASGAFHNFPIPVGGKTGTAEAVRRANYAWFVGFAPYDDPQIVVVVV IYQGGHGSYAGYVARDIFDAYFGLSKNNTGETFNVINLPIR
Specific function: Cell wall formation; PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross- linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786854, Length=361, Percent_Identity=32.9639889196676, Blast_Score=179, Evalue=8e-46, Organism=Escherichia coli, GI1786272, Length=301, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=7e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 - InterPro: IPR017790 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: NA
Molecular weight: Translated: 85799; Mature: 85799
Theoretical pI: Translated: 7.33; Mature: 7.33
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNESLKKKFYTFGAIILVLLVVLVSRLIYLQLIKGDYYREISMRQAIRRIPIEAPRGEIV CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHH DRYGVKLATNRPSFSVDIIKGEVVDSHLNETILKLMNILTKNNVKYKDDLPIYLDENGNP HHCCCEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCE YFNFKNSDEVSVKEETLKAREKAWKKANNIHENATAKEAWDILIKKFKIPKDMDPIEARK EEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH IMVVRQLMEEQGYNQYQPVEIAVDVDQKTIAEIEENHLELPGIMINVKPVRYYPYETLLS HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEEEEEEECCHHHHHH QTLGYIGRITQEDLKNLDMSKYKLTDLVGRSGLEALYEKYLRGKDGGQQVVVDNYGRLIK HHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEHHHHHHHHH NLGTEPPVPGDTIFLTIDKNIQEAAEQSLITTMQNIREGKYGESFPANIGAAVVVDVHTG HCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCC KVLALANIPGYDPNIFATGNPPKDVVNELFKSRDATVDPSPIFNYATQGAVPPGSTFKMA CEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHH VAFAALDTGVTTVDEKYLDPGIYPYTGQRNWAWPRTQGWVNVSDAIKYSTNTYFFEMGRR HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHEEECCCCEEEHHHHH MGIDKIVEYAKKFGLDQKTGIELYEAKGVIASPQYKREYYLGLIKSMVKTDTNPDGVITE CCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH EQYQKIVEIIDKGNLSDYNTFLQLEKMGIKDTKLQKKIWEMMYYAKHWSLTNTCSAAIGQ HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC GDNQFTPLQIASYVSTLINGGIRYRLHLVDKIISPEGKIVEETKPEVLDRIHISKEYLDA CCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHH IKLGMKGVTERGGTASGAFHNFPIPVGGKTGTAEAVRRANYAWFVGFAPYDDPQIVVVVV HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCEEEEEE IYQGGHGSYAGYVARDIFDAYFGLSKNNTGETFNVINLPIR EEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC >Mature Secondary Structure MNESLKKKFYTFGAIILVLLVVLVSRLIYLQLIKGDYYREISMRQAIRRIPIEAPRGEIV CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHH DRYGVKLATNRPSFSVDIIKGEVVDSHLNETILKLMNILTKNNVKYKDDLPIYLDENGNP HHCCCEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCE YFNFKNSDEVSVKEETLKAREKAWKKANNIHENATAKEAWDILIKKFKIPKDMDPIEARK EEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH IMVVRQLMEEQGYNQYQPVEIAVDVDQKTIAEIEENHLELPGIMINVKPVRYYPYETLLS HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEEEEEEECCHHHHHH QTLGYIGRITQEDLKNLDMSKYKLTDLVGRSGLEALYEKYLRGKDGGQQVVVDNYGRLIK HHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEHHHHHHHHH NLGTEPPVPGDTIFLTIDKNIQEAAEQSLITTMQNIREGKYGESFPANIGAAVVVDVHTG HCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCC KVLALANIPGYDPNIFATGNPPKDVVNELFKSRDATVDPSPIFNYATQGAVPPGSTFKMA CEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHH VAFAALDTGVTTVDEKYLDPGIYPYTGQRNWAWPRTQGWVNVSDAIKYSTNTYFFEMGRR HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHEEECCCCEEEHHHHH MGIDKIVEYAKKFGLDQKTGIELYEAKGVIASPQYKREYYLGLIKSMVKTDTNPDGVITE CCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH EQYQKIVEIIDKGNLSDYNTFLQLEKMGIKDTKLQKKIWEMMYYAKHWSLTNTCSAAIGQ HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC GDNQFTPLQIASYVSTLINGGIRYRLHLVDKIISPEGKIVEETKPEVLDRIHISKEYLDA CCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHH IKLGMKGVTERGGTASGAFHNFPIPVGGKTGTAEAVRRANYAWFVGFAPYDDPQIVVVVV HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCEEEEEE IYQGGHGSYAGYVARDIFDAYFGLSKNNTGETFNVINLPIR EEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11677609; 8930920 [H]