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The map label for this gene is minC

Identifier: 167040753

GI number: 167040753

Start: 2134652

End: 2135296

Strand: Reverse

Name: minC

Synonym: Teth514_2130

Alternate gene names: 167040753

Gene position: 2135296-2134652 (Counterclockwise)

Preceding gene: 167040754

Following gene: 167040752

Centisome position: 86.9

GC content: 34.26

Gene sequence:

>645_bases
ATGATAAAAGAAGCAATAAAAATTCAAGGGACAAAAGAAGGGCTGGTAATTGTATTAGAAGAGGATGTAGATATTGAAAC
ACTAAAAGAGAAAATAGTGAATAGAATTGAGAAATCTCTTAAATTTTTTGAGGGTGCAACTCTTACTGTGAGAGTAAAAA
GTTTAAGCGTCAAAGAAGAGAAATTACAAGAATTAAAAGACGTTATTTTTGAAAAATACGGTATTGAGGTGCGGATAAAA
AATTTTCAAGAAAAGCATATAAAAAATGTGACAGATGACGAAATATTTAATGGGTTAGAAGAGGGGATAACAAAATTTCA
TAAAGGTACTGTCAGATCAGGACAGGTTGTGAAATACCATGGTAATCTTGTAATAATTGGAGATGTGAATCCTGGAGGAT
TAGTACAAGCTGCCGGTAATATAGTTGTTATGGGGACGTTGAGGGGAATAGCTCATGCGGGATTTACTGGCAATAAAGAG
GCTGTAATCGTAGCTTCTTCCCTAAGAGCAATGCAGCTTAGAATAGCTAATGTTATTTCCAGGGCTCCAGATAAAGATGA
TGCTAGTGATTATCCCGAAATTGCAGTTGTTAAAAAAGGTAAAATTATTGTAAAGCCTCTTTACCATCTCAATGATTTGT
GGTAA

Upstream 100 bases:

>100_bases
TGGGGTGAGGATGTTTTATCCTCTTTTTTTCTTTAACAAGAAGGAAAATTACGATTTATGGAGAATATAGATAATAACGA
GGGTTTTACGGAGGTAGATT

Downstream 100 bases:

>100_bases
AATATTCTAAAAAATAATATTAATGGAATGGAGTGGTATGATGAGCGAAGCAATAGTTATAACTTCTGGAAAAGGTGGAG
TTGGGAAAACTACTTCTACT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIKEAIKIQGTKEGLVIVLEEDVDIETLKEKIVNRIEKSLKFFEGATLTVRVKSLSVKEEKLQELKDVIFEKYGIEVRIK
NFQEKHIKNVTDDEIFNGLEEGITKFHKGTVRSGQVVKYHGNLVIIGDVNPGGLVQAAGNIVVMGTLRGIAHAGFTGNKE
AVIVASSLRAMQLRIANVISRAPDKDDASDYPEIAVVKKGKIIVKPLYHLNDLW

Sequences:

>Translated_214_residues
MIKEAIKIQGTKEGLVIVLEEDVDIETLKEKIVNRIEKSLKFFEGATLTVRVKSLSVKEEKLQELKDVIFEKYGIEVRIK
NFQEKHIKNVTDDEIFNGLEEGITKFHKGTVRSGQVVKYHGNLVIIGDVNPGGLVQAAGNIVVMGTLRGIAHAGFTGNKE
AVIVASSLRAMQLRIANVISRAPDKDDASDYPEIAVVKKGKIIVKPLYHLNDLW
>Mature_214_residues
MIKEAIKIQGTKEGLVIVLEEDVDIETLKEKIVNRIEKSLKFFEGATLTVRVKSLSVKEEKLQELKDVIFEKYGIEVRIK
NFQEKHIKNVTDDEIFNGLEEGITKFHKGTVRSGQVVKYHGNLVIIGDVNPGGLVQAAGNIVVMGTLRGIAHAGFTGNKE
AVIVASSLRAMQLRIANVISRAPDKDDASDYPEIAVVKKGKIIVKPLYHLNDLW

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_THEP3 (B0KAD5)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665434.1
- GeneID:   5874921
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1448
- HOGENOM:   HBG399077
- OMA:   VESWERY
- ProtClustDB:   PRK00513
- BioCyc:   TPSE340099:TETH39_1448-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23773; Mature: 23773

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEAIKIQGTKEGLVIVLEEDVDIETLKEKIVNRIEKSLKFFEGATLTVRVKSLSVKEE
CCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHH
KLQELKDVIFEKYGIEVRIKNFQEKHIKNVTDDEIFNGLEEGITKFHKGTVRSGQVVKYH
HHHHHHHHHHHHHCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
GNLVIIGDVNPGGLVQAAGNIVVMGTLRGIAHAGFTGNKEAVIVASSLRAMQLRIANVIS
CCEEEEEECCCCCCEEECCCEEEEEEHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHH
RAPDKDDASDYPEIAVVKKGKIIVKPLYHLNDLW
CCCCCCCCCCCCCEEEEECCCEEEEEHHHHCCCC
>Mature Secondary Structure
MIKEAIKIQGTKEGLVIVLEEDVDIETLKEKIVNRIEKSLKFFEGATLTVRVKSLSVKEE
CCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHH
KLQELKDVIFEKYGIEVRIKNFQEKHIKNVTDDEIFNGLEEGITKFHKGTVRSGQVVKYH
HHHHHHHHHHHHHCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
GNLVIIGDVNPGGLVQAAGNIVVMGTLRGIAHAGFTGNKEAVIVASSLRAMQLRIANVIS
CCEEEEEECCCCCCEEECCCEEEEEEHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHH
RAPDKDDASDYPEIAVVKKGKIIVKPLYHLNDLW
CCCCCCCCCCCCCEEEEECCCEEEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA