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The map label for this gene is mdeA [H]

Identifier: 167040503

GI number: 167040503

Start: 1886948

End: 1887142

Strand: Reverse

Name: mdeA [H]

Synonym: Teth514_1872

Alternate gene names: 167040503

Gene position: 1887142-1886948 (Counterclockwise)

Preceding gene: 167040507

Following gene: 167040502

Centisome position: 76.8

GC content: 37.95

Gene sequence:

>195_bases
TTGTGTCAGTTAGCGGTAAGCTTGGGAGATACAGAAACATTAGTGGAAGTACCTTCCCTTATGACTCACAGAGGGTATCC
AAAAGAAAAACTTGTGGAGTTTGGATTGAGTGAAAGTATGGTGAGAATATCAGTAGGGCTCGAAGATTACAATGATATCA
TAGAGGATTTAGATCAAGCTCTTAATCAAATTTAG

Upstream 100 bases:

>100_bases
CTTTAGCATTAATTTTATCACAAGATTATTTAATCTGAAAAATTTTATCGGTTTTGGGCTAAATTAATTTGAGAAATGAC
AGTTTATAAGTAATTTAAGA

Downstream 100 bases:

>100_bases
GGATATATTGAGGTGAGAAAATGCCTATTGTCAATTTAAGCCTGCAAGTATTGCCTGTAGTTTCTGAAGAAAATATATAT
CCAATTGTAGATAAAGTCAT

Product: cystathionine beta-lyase/cystathionine gamma-synthase-like protein

Products: NA

Alternate protein names: L-methioninase [H]

Number of amino acids: Translated: 64; Mature: 64

Protein sequence:

>64_residues
MCQLAVSLGDTETLVEVPSLMTHRGYPKEKLVEFGLSESMVRISVGLEDYNDIIEDLDQALNQI

Sequences:

>Translated_64_residues
MCQLAVSLGDTETLVEVPSLMTHRGYPKEKLVEFGLSESMVRISVGLEDYNDIIEDLDQALNQI
>Mature_64_residues
MCQLAVSLGDTETLVEVPSLMTHRGYPKEKLVEFGLSESMVRISVGLEDYNDIIEDLDQALNQI

Specific function: Methionine biosynthesis; second step. [C]

COG id: COG0626

COG function: function code E; Cystathionine beta-lyases/cystathionine gamma-synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trans-sulfuration enzymes family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319307, Length=60, Percent_Identity=55, Blast_Score=69, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19922554, Length=58, Percent_Identity=53.448275862069, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000277
- InterPro:   IPR006237
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01053 Cys_Met_Meta_PP [H]

EC number: =4.4.1.11 [H]

Molecular weight: Translated: 7155; Mature: 7155

Theoretical pI: Translated: 3.92; Mature: 3.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQLAVSLGDTETLVEVPSLMTHRGYPKEKLVEFGLSESMVRISVGLEDYNDIIEDLDQA
CCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHH
LNQI
HHCC
>Mature Secondary Structure
MCQLAVSLGDTETLVEVPSLMTHRGYPKEKLVEFGLSESMVRISVGLEDYNDIIEDLDQA
CCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHH
LNQI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8586629; 9190812; 3365412 [H]