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The map label for this gene is pyrR

Identifier: 167040452

GI number: 167040452

Start: 1829512

End: 1830048

Strand: Reverse

Name: pyrR

Synonym: Teth514_1819

Alternate gene names: 167040452

Gene position: 1830048-1829512 (Counterclockwise)

Preceding gene: 167040454

Following gene: 167040451

Centisome position: 74.48

GC content: 38.73

Gene sequence:

>537_bases
TTGAAGATAAAAGCAGAGATAATGGATGAAAAAGCTATAGACAGAGCGCTCATACGAATAGCCCATGAAATTGTGGAAAG
GAATAAAGGCATTGAAGATGTGGTTTTGGTAGGTATTAAGACAAGAGGAGTGCCTTTAGCAGAAAGGATAGCGAAGTATA
TATCGCGAATTGAAGGGAAAAAGCCTCCAGTAGGGTCGCTGGATATCACCTTATATCGCGATGACCTCACGACAGACCTT
GAACAGCCTTTAGTGAAGAAAAAAGATATAGGTGTAGATGTAGTAGGTAAAATAGTGGTATTAGTGGATGACGTGATATA
CACAGGAAGGACTATAAGGGCTGCTATGGATGCAATTATCGACTTAGGAAGACCTAAAGCGATACAGCTGGCAGAACTAA
TTGACAGAGGGCATAGGGAATTGCCTATAAAGCCAGATTATGTAGGTAAAAATGTTCCAACATCAAAAAATGAAATAGTA
AATGTAATGTTGGAGGAAGTAGACAAAGTAAACAGAGTTGTAATAACTGAAAAGTAG

Upstream 100 bases:

>100_bases
AAAGTTCTTTAAGCAGTCCTGTGAGGCTGGCAAGGTTACCATAATGTAGCATAAAAAACTTCTTGTCAGTGCAAGAAGTT
TTTTTGTGGAGGTTGTGAAG

Downstream 100 bases:

>100_bases
CACCTTTAATTTAGCCCAGCGAGGCTAAAAAGGGAGAATGATAGATATTCTCCCGGAGTATTAAACTCTAAAAAGGGAGG
ATTTTTTATGCCAAAATTCA

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKIKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAERIAKYISRIEGKKPPVGSLDITLYRDDLTTDL
EQPLVKKKDIGVDVVGKIVVLVDDVIYTGRTIRAAMDAIIDLGRPKAIQLAELIDRGHRELPIKPDYVGKNVPTSKNEIV
NVMLEEVDKVNRVVITEK

Sequences:

>Translated_178_residues
MKIKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAERIAKYISRIEGKKPPVGSLDITLYRDDLTTDL
EQPLVKKKDIGVDVVGKIVVLVDDVIYTGRTIRAAMDAIIDLGRPKAIQLAELIDRGHRELPIKPDYVGKNVPTSKNEIV
NVMLEEVDKVNRVVITEK
>Mature_178_residues
MKIKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAERIAKYISRIEGKKPPVGSLDITLYRDDLTTDL
EQPLVKKKDIGVDVVGKIVVLVDDVIYTGRTIRAAMDAIIDLGRPKAIQLAELIDRGHRELPIKPDYVGKNVPTSKNEIV
NVMLEEVDKVNRVVITEK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_THEP3 (B0KA38)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665337.1
- ProteinModelPortal:   B0KA38
- SMR:   B0KA38
- GeneID:   5875049
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1347
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- BioCyc:   TPSE340099:TETH39_1347-MONOMER
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19908; Mature: 19908

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAERIAKYISRIEGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
KPPVGSLDITLYRDDLTTDLEQPLVKKKDIGVDVVGKIVVLVDDVIYTGRTIRAAMDAII
CCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLGRPKAIQLAELIDRGHRELPIKPDYVGKNVPTSKNEIVNVMLEEVDKVNRVVITEK
HCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEECC
>Mature Secondary Structure
MKIKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAERIAKYISRIEGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
KPPVGSLDITLYRDDLTTDLEQPLVKKKDIGVDVVGKIVVLVDDVIYTGRTIRAAMDAII
CCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLGRPKAIQLAELIDRGHRELPIKPDYVGKNVPTSKNEIVNVMLEEVDKVNRVVITEK
HCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA