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The map label for this gene is pyrK [H]

Identifier: 167040448

GI number: 167040448

Start: 1825376

End: 1826104

Strand: Reverse

Name: pyrK [H]

Synonym: Teth514_1815

Alternate gene names: 167040448

Gene position: 1826104-1825376 (Counterclockwise)

Preceding gene: 167040449

Following gene: 167040447

Centisome position: 74.31

GC content: 37.04

Gene sequence:

>729_bases
ATGGAAACCAGGATATTGTCTAATGAAAAGATAGCCACAGGTATTTATAAAATGGTATTTGAGTGGTATGAGAAAGCACA
CCCAGGACAATTTGTGATGGTAGACTGCAAAGGCAAGACTTTTTTAAAGAGGCCTATTAGCGTATGCTCTGTTGAGGACA
AATCCTTGACAATTGTGTACCAAGTTAAAGGGGAAGGTACAAAGAATTTATCTCAAATGAAAAGTGGGGAGATAATTGAG
GTAACAGGACCTCATGGAAATGGTTTTGAGATAAGGGAGGACAAAAATGTTTTAATAGTAGGAGGGGGAATAGGCATTCC
TCCCCTTCTATACATTGCTAAAAAAATCAAAGCAAAAAAATTGTATATTGCGTTGGGATTTAGAAGTGAAACTTTTCTTG
TAGAAGAGTTTAAAAATTTGGGAGAAGTTATTGTCACGACAGAGGACGGAAGTTTTGGGAAAAAAGGAATGGTGACACAA
GTAATTGAGGATATAATTGATAAGATTGACATAATATATGGCTGTGGACCAAAACCTATGCTAAAGATATTACAAGATAT
TTCTCTTAAAAATAACATTCCTTGTCAAATATCTGTAGAAGAAAGGATGGCTTGTGGCATAGGAGCTTGTCTTGTATGCG
CTTGCAAAGTGAAAAAAGATGGTGGTTTTGCGTACAAAAGAGTGTGCAAAGATGGTCCCGTCTTTTGGGCAGAGGAGGTG
GAGTTTTGA

Upstream 100 bases:

>100_bases
ATGAGTATGCACAAGCGGCGAGAGCAGAAGTAATTCTTATGACAGGTATGATTAACAATGGGCTTGTTAAAAGAAAATAC
ATCGCTTGTTGAGGTGAAAA

Downstream 100 bases:

>100_bases
ATTTACAAGTTGAAGTTGGGGGACTTAAGTTAAAAAATCCGGTGATGACAGCTTCAGGTACTTTTGGGTTTGGAAGAGAG
TACGGAGAATATATTGATTT

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
METRILSNEKIATGIYKMVFEWYEKAHPGQFVMVDCKGKTFLKRPISVCSVEDKSLTIVYQVKGEGTKNLSQMKSGEIIE
VTGPHGNGFEIREDKNVLIVGGGIGIPPLLYIAKKIKAKKLYIALGFRSETFLVEEFKNLGEVIVTTEDGSFGKKGMVTQ
VIEDIIDKIDIIYGCGPKPMLKILQDISLKNNIPCQISVEERMACGIGACLVCACKVKKDGGFAYKRVCKDGPVFWAEEV
EF

Sequences:

>Translated_242_residues
METRILSNEKIATGIYKMVFEWYEKAHPGQFVMVDCKGKTFLKRPISVCSVEDKSLTIVYQVKGEGTKNLSQMKSGEIIE
VTGPHGNGFEIREDKNVLIVGGGIGIPPLLYIAKKIKAKKLYIALGFRSETFLVEEFKNLGEVIVTTEDGSFGKKGMVTQ
VIEDIIDKIDIIYGCGPKPMLKILQDISLKNNIPCQISVEERMACGIGACLVCACKVKKDGGFAYKRVCKDGPVFWAEEV
EF
>Mature_242_residues
METRILSNEKIATGIYKMVFEWYEKAHPGQFVMVDCKGKTFLKRPISVCSVEDKSLTIVYQVKGEGTKNLSQMKSGEIIE
VTGPHGNGFEIREDKNVLIVGGGIGIPPLLYIAKKIKAKKLYIALGFRSETFLVEEFKNLGEVIVTTEDGSFGKKGMVTQ
VIEDIIDKIDIIYGCGPKPMLKILQDISLKNNIPCQISVEERMACGIGACLVCACKVKKDGGFAYKRVCKDGPVFWAEEV
EF

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 26843; Mature: 26843

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRILSNEKIATGIYKMVFEWYEKAHPGQFVMVDCKGKTFLKRPISVCSVEDKSLTIVY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCEEEECCCCEEEEE
QVKGEGTKNLSQMKSGEIIEVTGPHGNGFEIREDKNVLIVGGGIGIPPLLYIAKKIKAKK
EECCCCCCCHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCEE
LYIALGFRSETFLVEEFKNLGEVIVTTEDGSFGKKGMVTQVIEDIIDKIDIIYGCGPKPM
EEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCHHH
LKILQDISLKNNIPCQISVEERMACGIGACLVCACKVKKDGGFAYKRVCKDGPVFWAEEV
HHHHHHHCCCCCCCEEEEHHHHHHCCCCHHEEEEEEEECCCCHHHHHHHCCCCEEEEECC
EF
CC
>Mature Secondary Structure
METRILSNEKIATGIYKMVFEWYEKAHPGQFVMVDCKGKTFLKRPISVCSVEDKSLTIVY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCEEEECCCCEEEEE
QVKGEGTKNLSQMKSGEIIEVTGPHGNGFEIREDKNVLIVGGGIGIPPLLYIAKKIKAKK
EECCCCCCCHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCEE
LYIALGFRSETFLVEEFKNLGEVIVTTEDGSFGKKGMVTQVIEDIIDKIDIIYGCGPKPM
EEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCHHH
LKILQDISLKNNIPCQISVEERMACGIGACLVCACKVKKDGGFAYKRVCKDGPVFWAEEV
HHHHHHHCCCCCCCEEEEHHHHHHCCCCHHEEEEEEEECCCCHHHHHHHCCCCEEEEECC
EF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]