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The map label for this gene is mpg1 [H]

Identifier: 167040423

GI number: 167040423

Start: 1796816

End: 1797862

Strand: Reverse

Name: mpg1 [H]

Synonym: Teth514_1787

Alternate gene names: 167040423

Gene position: 1797862-1796816 (Counterclockwise)

Preceding gene: 167040424

Following gene: 167040422

Centisome position: 73.17

GC content: 34.19

Gene sequence:

>1047_bases
ATGAAGGCATTGCTATTGGCAGGAGGTTTGGGAACAAGGCTAAGACCTCTTACAGATGACCTGCCAAAACCAATGGTTCC
TATCATGGGAAGACCTCTTTTAGAAAGGATTATTTTAAACCTTAAAAAAAGTGGAGTAGATGAAATTGTAATAAGTACTT
ATTATAAGTCTCAGTACATTGAAGACTACTTCAAACAAAAAGAGGACTTAGGTGTAAAAATACACTTCATTACAGAAGAG
TCCCCTTTAGGGACTGGTGGAGCAATAAAAAACGCCGAAAAATTTTTTGATGATACTTTCCTCATTTTAAACTCTGATAT
TGTCAGTGATATTGACTATGCAGATTTGATAAAATACCACAAGAGAAGAAGAGCTCAAGTAACTATTGCATCTATTGAAG
TAAGAGATACTTCTCAGTACGGAGTTATAGAATTTGATGAAAAAGGCTTTATAACTGCTTTCAAAGAAAAGCCCAAACCA
GGCGAGAGCAATTCTAAATATATTAACGCAGGAGTATATGTATTTGAACCTGAGGTGCTAAAAGAAATTCCTGAAAATAC
AGTGATATCTGTAGAAAGAGAGACATATCCCAAACTTTTGGAAAAAGGGTATAGAATGGCTATTTATAAATTTAACGGCT
ACTGGATAGATATAGGTACAATAGACAAATACAAAAAAGTTCATGAGGACATTTTAAAAGGAAAATCAAGATTTGTAAGT
ACTACTTCCTCAAGAGGCATAATTTTAGGAGACAATGTTAAAATTCATCCTACCGCAAGAGTGATAGGACCTGCTTATAT
TGGAAATAATACTGAAATTGATGCCTATGCTACAGTTGGTCCGTATACAGTAATTGGGAATAACTGTCGAATAGGTCAAG
AGAGCAAAGTATCCCAAAGTGTATTGTGGGATAATGTAAAAGTCCGCAGGTTTGCAAGATTAGACAATGCAGTTGTAACT
TCAGAATGTATAGTAGAGGTGAATATGGAAATTAAAAATACAGTGTTTACACCTAATAGATTAGCAAGTACTAAAATGAC
AACTTAA

Upstream 100 bases:

>100_bases
CTTAGTTTTTATCGCTCTTATAAATTATATCACTTGTATCACGCCCTTCTTTTGTTTTTAAGTTTAATTTTTGAAAAACT
TCATAAAGGAGGGGTCTTTT

Downstream 100 bases:

>100_bases
TACTAAACAAACTAAGAAGGGGGCGTGATATGATGAGCGTATTGGGGAGAAATGTAGCATTTTTGAGTACTTATCCACCA
AGAGAATGTGGCATTGCTAC

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKALLLAGGLGTRLRPLTDDLPKPMVPIMGRPLLERIILNLKKSGVDEIVISTYYKSQYIEDYFKQKEDLGVKIHFITEE
SPLGTGGAIKNAEKFFDDTFLILNSDIVSDIDYADLIKYHKRRRAQVTIASIEVRDTSQYGVIEFDEKGFITAFKEKPKP
GESNSKYINAGVYVFEPEVLKEIPENTVISVERETYPKLLEKGYRMAIYKFNGYWIDIGTIDKYKKVHEDILKGKSRFVS
TTSSRGIILGDNVKIHPTARVIGPAYIGNNTEIDAYATVGPYTVIGNNCRIGQESKVSQSVLWDNVKVRRFARLDNAVVT
SECIVEVNMEIKNTVFTPNRLASTKMTT

Sequences:

>Translated_348_residues
MKALLLAGGLGTRLRPLTDDLPKPMVPIMGRPLLERIILNLKKSGVDEIVISTYYKSQYIEDYFKQKEDLGVKIHFITEE
SPLGTGGAIKNAEKFFDDTFLILNSDIVSDIDYADLIKYHKRRRAQVTIASIEVRDTSQYGVIEFDEKGFITAFKEKPKP
GESNSKYINAGVYVFEPEVLKEIPENTVISVERETYPKLLEKGYRMAIYKFNGYWIDIGTIDKYKKVHEDILKGKSRFVS
TTSSRGIILGDNVKIHPTARVIGPAYIGNNTEIDAYATVGPYTVIGNNCRIGQESKVSQSVLWDNVKVRRFARLDNAVVT
SECIVEVNMEIKNTVFTPNRLASTKMTT
>Mature_348_residues
MKALLLAGGLGTRLRPLTDDLPKPMVPIMGRPLLERIILNLKKSGVDEIVISTYYKSQYIEDYFKQKEDLGVKIHFITEE
SPLGTGGAIKNAEKFFDDTFLILNSDIVSDIDYADLIKYHKRRRAQVTIASIEVRDTSQYGVIEFDEKGFITAFKEKPKP
GESNSKYINAGVYVFEPEVLKEIPENTVISVERETYPKLLEKGYRMAIYKFNGYWIDIGTIDKYKKVHEDILKGKSRFVS
TTSSRGIILGDNVKIHPTARVIGPAYIGNNTEIDAYATVGPYTVIGNNCRIGQESKVSQSVLWDNVKVRRFARLDNAVVT
SECIVEVNMEIKNTVFTPNRLASTKMTT

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=336, Percent_Identity=33.3333333333333, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI11761619, Length=332, Percent_Identity=33.1325301204819, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI31881779, Length=388, Percent_Identity=24.2268041237113, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI45447090, Length=388, Percent_Identity=24.2268041237113, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1788351, Length=253, Percent_Identity=28.0632411067194, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789837, Length=374, Percent_Identity=24.331550802139, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790224, Length=253, Percent_Identity=26.4822134387352, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788355, Length=223, Percent_Identity=26.9058295964126, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=340, Percent_Identity=34.1176470588235, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17509979, Length=354, Percent_Identity=27.1186440677966, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17509981, Length=341, Percent_Identity=26.3929618768328, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=325, Percent_Identity=33.8461538461538, Blast_Score=173, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21355443, Length=334, Percent_Identity=32.6347305389222, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24644084, Length=334, Percent_Identity=32.6347305389222, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24653912, Length=373, Percent_Identity=26.5415549597855, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 39298; Mature: 39298

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLLAGGLGTRLRPLTDDLPKPMVPIMGRPLLERIILNLKKSGVDEIVISTYYKSQYI
CCEEEEECCCCCCCCCCHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
EDYFKQKEDLGVKIHFITEESPLGTGGAIKNAEKFFDDTFLILNSDIVSDIDYADLIKYH
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHCCEEEEEECHHHCCCCHHHHHHHH
KRRRAQVTIASIEVRDTSQYGVIEFDEKGFITAFKEKPKPGESNSKYINAGVYVFEPEVL
HHCCEEEEEEEEEEECCCCCCEEEECCCCCEEEECCCCCCCCCCCCEEECCEEEECHHHH
KEIPENTVISVERETYPKLLEKGYRMAIYKFNGYWIDIGTIDKYKKVHEDILKGKSRFVS
HHCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCEEEECCCHHHHHHHHHHHHCCCHHEEE
TTSSRGIILGDNVKIHPTARVIGPAYIGNNTEIDAYATVGPYTVIGNNCRIGQESKVSQS
ECCCCCEEECCCEEEEECCEEECCEEECCCCCEEEEEECCCEEEECCCCCCCCCCHHHHH
VLWDNVKVRRFARLDNAVVTSECIVEVNMEIKNTVFTPNRLASTKMTT
HHHCCHHHHHHHHHCCCEEEEEEEEEEEEEECCEEECCCHHCCCCCCC
>Mature Secondary Structure
MKALLLAGGLGTRLRPLTDDLPKPMVPIMGRPLLERIILNLKKSGVDEIVISTYYKSQYI
CCEEEEECCCCCCCCCCHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
EDYFKQKEDLGVKIHFITEESPLGTGGAIKNAEKFFDDTFLILNSDIVSDIDYADLIKYH
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHCCEEEEEECHHHCCCCHHHHHHHH
KRRRAQVTIASIEVRDTSQYGVIEFDEKGFITAFKEKPKPGESNSKYINAGVYVFEPEVL
HHCCEEEEEEEEEEECCCCCCEEEECCCCCEEEECCCCCCCCCCCCEEECCEEEECHHHH
KEIPENTVISVERETYPKLLEKGYRMAIYKFNGYWIDIGTIDKYKKVHEDILKGKSRFVS
HHCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCEEEECCCHHHHHHHHHHHHCCCHHEEE
TTSSRGIILGDNVKIHPTARVIGPAYIGNNTEIDAYATVGPYTVIGNNCRIGQESKVSQS
ECCCCCEEECCCEEEEECCEEECCEEECCCCCEEEEEECCCEEEECCCCCCCCCCHHHHH
VLWDNVKVRRFARLDNAVVTSECIVEVNMEIKNTVFTPNRLASTKMTT
HHHCCHHHHHHHHHCCCEEEEEEEEEEEEEECCEEECCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]