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The map label for this gene is ttdA [C]

Identifier: 167040415

GI number: 167040415

Start: 1784503

End: 1785345

Strand: Reverse

Name: ttdA [C]

Synonym: Teth514_1779

Alternate gene names: 167040415

Gene position: 1785345-1784503 (Counterclockwise)

Preceding gene: 167040417

Following gene: 167040414

Centisome position: 72.66

GC content: 39.15

Gene sequence:

>843_bases
TTGAGGGAAATAAAAGCTAGTCAAATTGTGGAAGTTGTCAAAAAGCTGTGTATTGAAGCGAATTATAATTTACCGGATGA
TATATTAAAAGGGCTCAAAATCCGGAAGAAGGAGGAAAAAAGTCCTTTAGGCCAAAAAATTCTTGAAGATATAATTTTAA
ATGCTGAAATAGCTATGCAAGAGAAAATGGCTATATGTCAGGATACAGGAATGGCCGTGGTTTTTGTAGATATAGGACAA
GAAGTACGCGTTGTAGATGGAGATTTGGAAGAGGCTATAAATGAAGGAGTGAGATTGGGTTATAAAGAGGGATATTTGAG
AAAGTCTGTTGTGAAAAGCCCTATAGAAAGAATTAACACAAATGACAATACTCCTGCGGTAATACATTATCGTGTGTGTA
GAGGAGATAGACTCATTATAACTGTAATGCCAAAAGGAGCTGGCAGCGAAAATATGAGTGCTTTGAAGATGTTAAAGCCT
TCAGATGGTTTAGAAGGGGTAAAAAGATTTGTAATAGAGACTGTGGAAAAATCCGGTCCTAACGCTTGTCCTCCTCTGAT
TGTGGGGGTTGGTCTTGGAGGAGATTTTGAATATGCAGCCTATCTAGCGAAAAAAGCACTGTTGAGGAAAGTCGGCGAAA
GGCATCAGGATATTTTAATTGCTAGGTTGGAAGAAGAGCTTTTAAATGAGATAAACTCTTTAGGCATTGGGCCGATGGGC
CTTGGAGGGACTACTACTGCCCTAGATGTCCACATAGAAGTATATCCTACCCACATTGCTTCTTTGCCTGTTGCAGTAAA
TTTGGGATGCCATGCTACGAGACACGCTACTTTTGTATTATAA

Upstream 100 bases:

>100_bases
TATGCAATAAACCATTATAAGAGATTTTCAAAGAAATTGCAAAATTGATATTAAAAATAGTATTATAAATCATAAAGGAA
TAAGTGCGAGGTGAAAAATT

Downstream 100 bases:

>100_bases
TTATGTTTGGAGGGAAAACATGTACAGAAAATTAAATACACCTTTACTAGATGAAGTAACAGTACAATTGAAAGCTGGGG
ATTTGATTTTGCTCTCAGGA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQEKMAICQDTGMAVVFVDIGQ
EVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINTNDNTPAVIHYRVCRGDRLIITVMPKGAGSENMSALKMLKP
SDGLEGVKRFVIETVEKSGPNACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL

Sequences:

>Translated_280_residues
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQEKMAICQDTGMAVVFVDIGQ
EVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINTNDNTPAVIHYRVCRGDRLIITVMPKGAGSENMSALKMLKP
SDGLEGVKRFVIETVEKSGPNACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL
>Mature_280_residues
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQEKMAICQDTGMAVVFVDIGQ
EVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINTNDNTPAVIHYRVCRGDRLIITVMPKGAGSENMSALKMLKP
SDGLEGVKRFVIETVEKSGPNACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=283, Percent_Identity=33.9222614840989, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1790564, Length=240, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787897, Length=241, Percent_Identity=31.1203319502075, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30633; Mature: 30633

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQ
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCHHHHH
EKMAICQDTGMAVVFVDIGQEVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINT
HHHHHHHCCCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
NDNTPAVIHYRVCRGDRLIITVMPKGAGSENMSALKMLKPSDGLEGVKRFVIETVEKSGP
CCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
NACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL
CCCCCEEEEEEEEEEECHHHCCCEEEECCCCCCCCEEEEC
>Mature Secondary Structure
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQ
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCHHHHH
EKMAICQDTGMAVVFVDIGQEVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINT
HHHHHHHCCCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
NDNTPAVIHYRVCRGDRLIITVMPKGAGSENMSALKMLKPSDGLEGVKRFVIETVEKSGP
CCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
NACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL
CCCCCEEEEEEEEEEECHHHCCCEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]